Inflammasome News and Research

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Neonates exposed to SARS-CoV-2 in utero at higher risk of respiratory distress, study finds

Researchers found that neonates born to mothers with SARS-CoV-2 infection face an increased risk of respiratory distress, potentially due to an inflammatory response triggered by prenatal exposure.

29 Jan 2024

Infammasomes provide a therapeutic target against human diseases

The structure of inflammasomes and their role in diseases.

9 Jan 2024

Common inflammation pathway turns anthrax toxin into killer

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system.

26 Dec 2023

Forsythiae Fructus shows promise in relieving chemotherapy side effects

Chemotherapy-induced nausea and vomiting (CINV) are among the most prevalent and distressing side effects faced by patients undergoing antineoplastic treatments.

19 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

Scientists unveil 3D structure of key immune system component

An international team of researchers from LMU and the Helmholtz Centre for Infection Research has visualized the structure of the so-called ASC speck.

8 Dec 2023

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

A study by Brigham investigators revealed how genetic changes in certain types of brain cells may contribute to the inflammatory response seen in Alzheimer's disease.

28 Nov 2023

Researchers identify biomarkers for checkpoint inhibitor-induced hyperprogression of melanoma cells

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system to fight them.

24 Nov 2023

Study shows depression increases disability risk in rheumatoid arthritis sufferers

The interactions between rheumatoid arthritis (RA) and major depressive disorder (MDD).

7 Nov 2023

LMU medical scientists discover new mechanism of alarmin release

LMU medical scientists have demonstrated that important pro-inflammatory mediators are released into the bloodstream through tiny pores in the cell membrane at a very early stage of the immune response.

2 Nov 2023

Is COVID-19 a risk factor for Alzheimer's disease?

The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.

23 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.

12 Oct 2023

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation.

11 Oct 2023

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Researchers explore the potential utility of ginger essential oil in preventing NASH.

29 Aug 2023

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Inflammasome News and Research

Neonates exposed to SARS-CoV-2 in utero at higher risk of respiratory distress, study finds

Infammasomes provide a therapeutic target against human diseases

Common inflammation pathway turns anthrax toxin into killer

Forsythiae Fructus shows promise in relieving chemotherapy side effects

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Scientists unveil 3D structure of key immune system component

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

Researchers identify biomarkers for checkpoint inhibitor-induced hyperprogression of melanoma cells

Study shows depression increases disability risk in rheumatoid arthritis sufferers

LMU medical scientists discover new mechanism of alarmin release

Is COVID-19 a risk factor for Alzheimer's disease?

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Ketogenic diets, gut microbiota, and health effects

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Study shows link between regulatory T cells and anxiety, depression, Alzheimer's disease

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

NLRP3 inflammasome plays a role in podocyte aging

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