Neglected Tropical Disease News and Research

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Scientists study immune molecules inside mycetoma grains

Mycetoma is a common neglected disease caused by either fungi or bacteria which organize themselves into grains—areas of inflammation surrounded by a collagen capsule.

From PLOS ONE 12 Jul 2019

Consortium receives EU grant to develop new treatment for leishmaniasis

Professor Sanjeev Krishna and colleagues at St George's, University of London are heading a consortium that has been awarded EUR3.75 million to develop a treatment for one of the world's most neglected tropical diseases, leishmaniasis.

18 Jun 2019

Simple prevention methods could reduce tungiasis in children, study suggests

Tungiasis is a neglected tropical disease caused by penetrated sand fleas which burrow into the skin of the feet.

21 May 2019

UGR scientists break new ground in Chagas disease research

A team of scientists from the University of Granada has broken new ground in Chagas disease research.

10 May 2019

United Nations sounds alarm bell on drug-resistant infections

According to a new report from a United Nations Committee, antibiotic resistance levels are at an all time high and are the reason behind common infections becoming difficult to treat.

30 Apr 2019

GARDP forms multi-actor partnerships to discover new antibiotics

Multi-actor partnership tests natural products and compound libraries for antibacterial activity Discovery efforts will focus on World Health Organization's priority pathogens The Global Antibiotic Research and Development Partnership is partnering with Calibr, the Helmholtz Centre for Infection Research, in particular its location Helmholtz-Institute for Pharmaceutical Research Saarland, and the University of Queensland's Community for Open Antimicrobial Drug Discovery in its efforts to develop and ensure new antibiotics are globally available to all patients who need them.

11 Apr 2019

Researchers engineer a promising treatment for African sleeping sickness

Researchers have turned a fungus into a disease-curing factory through modern genetic engineering and patience.

4 Apr 2019

Scientists create new models of tropical eye worm for development of anti-filarial drugs

Researchers at the LSTM's Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis.

30 Mar 2019

New survey indicates need of attention to neglected tropical diseases

Although neglected diseases account for 11% of the global disease burden, they are targeted by only a small proportion of the new drugs developed every year.

22 Mar 2019

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

The Global Antibiotic Research and Development Partnership and Evotec AG are today announcing the formation of a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance.

19 Mar 2019

Shorter treatment for Chagas disease found to be effective and safer than standard treatment

A two-week treatment course for adult patients with chronic Chagas disease showed, when compared to placebo, similar efficacy and significantly fewer side effects than the standard treatment duration of eight weeks, according to the results of a clinical trial in Bolivia led by the Drugs for Neglected Diseases initiative.

14 Mar 2019

Researchers unravel how the immune system responds to diffuse cutaneous leishmanisis

In diffuse cutaneous leishmanisis, a rare form of leishmaniasis, parasites grow uncontrolled in skin lesions across the body.

8 Mar 2019

GARDP and Penta join forces to deal with drug-resistant infections in children

The Global Antibiotic Research & Development Partnership and Penta, the pediatric infectious diseases research network, have joined forces to tackle drug-resistant infections in children.

5 Mar 2019

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms.

1 Feb 2019

New drug for sleeping sickness approved in the Democratic Republic of Congo

Marketing authorization of fexinidazole for the treatment of Trypanosoma brucei gambiense human African trypanosomiasis (HAT), more commonly known as sleeping sickness, has been granted in the Democratic Republic of Congo (DRC).

31 Jan 2019

Combination therapy shows high efficacy in treating people with leishmaniasis and HIV

The results of clinical trials conducted in Ethiopia by the Drugs for Neglected Diseases initiative, in partnership with Médecins Sans Frontières, the University of Gondar, and Addis Ababa University, open the way for more effective and safer treatments for people with both HIV and visceral leishmaniasis, a group of patients who have historically suffered from poor treatment options.

18 Jan 2019

Physical contact with primates puts people at risk of infection with new diseases

Animal diseases that infect humans are a major threat to human health, and diseases often spillover to humans from nonhuman primates. Now, researchers reporting in PLOS Neglected Tropical Diseases have carried out an extensive social sciences evaluation of how populations in Cameroon interact with nonhuman primates, pointing toward behaviors that could put people at risk of infection with new diseases.

28 Dec 2018