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Most clinical trials fail to reflect America’s racial and ethnic diversity

A new study finds just 6% of clinical trials used to approve new drugs in the U.S. reflect the country's racial and ethnic makeup, with an increasing trend of trials underrepresenting Black and Hispanic individuals.

12 Dec 2025

Urine cfDNA patterns emerge as a promising tool for diagnosing bladder cancer

Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive procedures like cystoscopies.

4 Dec 2025

Study demonstrates a safer strategy for allogeneic stem cell transplants

In preclinical studies, researchers found that priming the immune system with a Treg-expanding therapy before stem cell transplant boosted survival, protected vital organs, and promoted a balanced gut microbiome-offering hope for safer, more effective treatment of blood cancers.

27 Nov 2025

Freezing cells for success: DMSO-free redefining the future of cryopreservation

Cryopreservation plays a crucial role in cell biology research, bioprocessing, and biomanufacturing. Traditionally, DMSO (dimethyl sulfoxide) has been the cryoprotectant of choice for preserving cells.

From NIPPON Genetics EUROPE GmbH 25 Nov 2025

Development of a polygenic risk score for pelvic organ prolapse in Chinese women

Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly impairs women's quality of life, yet genetic insights into non-European populations and comprehensive risk models that integrate genetic and clinical data remain insufficiently explored.

24 Nov 2025

New robotic testing method reveals overlooked proprioception deficits after stroke

A decade ago, at age 55, Don Lewis suffered a stroke in his sleep. When he woke up, he couldn't move his left arm or leg. Lewis' neighbor realized his truck hadn't moved in two days and called 911 for a welfare check. When paramedics found him, he was paralyzed on one side.

17 Nov 2025

SwRI-developed single-use 3D-printed bioreactor harvests induced Pluripotent Stem Cells

Southwest Research Institute (SwRI) has demonstrated a new application for its cell-expansion bioreactor to advance tissue engineering and cell-based therapies for treatment of injuries and diseases.

12 Nov 2025

Researchers develop multiethnic model for identifying individuals with skin cancer

Researchers at the University of California San Diego School of Medicine have developed a new approach for identifying individuals with skin cancer that combines genetic ancestry, lifestyle and social determinants of health using a machine learning model.

10 Nov 2025

Breakthrough study maps impact of thousands of variants in heart disease gene

An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more than 17,000 variants in a major gene associated with the development of premature atherosclerotic heart disease.

31 Oct 2025

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Low-cost biosensor identifies altered protein levels associated with psychiatric disorders

Brazilian researchers have developed a low-cost, portable biosensor that can quickly identify a protein whose altered levels are associated with psychiatric disorders, such as depression, schizophrenia, and bipolar disorder.

30 Oct 2025

AI-powered LifeClock forecasts diseases years before symptoms appear

Researchers have developed LifeClock, an AI-driven biological clock trained on over 24 million electronic health records to estimate biological age across the human lifespan. The model accurately predicts disease risk years in advance, revealing distinct developmental and aging processes.

28 Oct 2025

New drug combination shows promise in treating colorectal cancer

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

22 Oct 2025

HCS-3DX platform enables large-scale, high-precision screening of cellular models

The HCS-3DX platform performs automated analysis of three-dimensional cell cultures, known as spheroids.

21 Oct 2025

Molecular evidence connects higher childhood cognitive function to longer lifespan

Researchers led by Dr. W. David Hill at the University of Edinburgh have identified a significant genetic correlation between childhood cognitive function and longevity, providing the first molecular genetic evidence that intelligence measured in youth shares genetic factors with lifespan.

21 Oct 2025

New 3D human brain tissue platform integrates all major brain cell types into a single culture

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture.

17 Oct 2025

New personalized therapy boosts tamoxifen effectiveness in breast cancer patients

Breast cancer is the most common cancer among women worldwide (WHO, 2023). The Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP) has now developed a new therapy in a clinical study that tailors hormone treatment for breast cancer to the individual patient.

16 Oct 2025