Shigella News and Research

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Study offers insights into how Shigella delivers bacterial proteins into our cells

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

Naturally occurring phage A1-1 kills dysentery-causing bacteria in sub-Saharan Africa, southern Asia

Phages are viruses that infect bacteria and can also be used to treat human infections. However, as with antibiotics, bacteria can readily evolve resistance to phage attack, highlighting a key limitation to the use of phages as therapeutics.

21 Nov 2021

Certain intestinal bacteria induce cross-reactive IgA responses to the SARS-CoV-2 spike RBD

A new study finds that human gut bacteria can induce antibodies of the immunoglobulin A (IgA) subtype that cross-react with the SARS-CoV-2 spike RBD.

15 Aug 2021

CEPI and IVI announce new research program to expand access to COVID-19 vaccines in Africa

The Coalition for Epidemic Preparedness Innovations and the International Vaccine Institute today announced a new programme of clinical research which aims to expand access to COVID-19 vaccines in Africa.

20 Jul 2021

Campylobacter infection can also be spread through sexual contact

Campylobacter infection, one of the most common foodborne illnesses in the Western world, can also be spread through sexual contact, according to a new research discovery by an OU Hudson College of Public Health faculty member, working in conjunction with colleagues in Denmark.

21 May 2021

Study could lead to new antibiotics to fight bacterial infections

One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead, a new study led by UT Southwestern scientists shows.

21 May 2021

A new strain of common probiotic can potentially be more effective at protecting infant health

Researchers at the University of Helsinki have created a strain of the Lacticaseibacillus rhamnosus GG probiotic that is able to utilize both lactose and casein as well as reproduce in dairy products.

29 Apr 2021

How could AI be used to predict infection outcomes?

Professor Frankel speaks to News-Medical about his latest research that investigated whether AI could be used to predict infection outcomes.

23 Mar 2021

Antimicrobial resistance to critical drugs spirals in low- and middle-income countries

As antibiotic use grows in lower-income countries so does antibiotic resistance, says report.

20 Feb 2021

Cellid, IVI sign research service contract to evaluate immunogenicity of COVID-19 vaccine

Cellid and the International Vaccine Institute have exchanged a collaborative research agreement to analyze the immunogenicity of the COVID-19 vaccine "AdCLD-CoV19".

5 Jan 2021

Vi-DT typhoid conjugate vaccine met primary endpoints in phase III study

Vi-DT typhoid conjugate vaccine, developed jointly by the International Vaccine Institute (IVI) and SK bioscience, has met the primary endpoints in a phase III study in Nepal.

17 Dec 2020

IVI hosts virtual State Forum to promote partnership and equity in global health

The International Vaccine Institute (IVI) hosted a virtual State Forum today to advocate for multilateral cooperation through vaccine diplomacy.

13 Oct 2020

Azelastine antihistamine inhibits SARS-CoV-2 infection in nasal tissue in vitro

In a study published on the bioRxiv preprint server, researchers from the University of Pécs, University of Vienna, and CEBINA GmbH, Vienna, show the ability of the antihistamine azelastine to inhibit SARS-CoV-2 infection in human nasal tissue in vitro.

16 Sep 2020

Finland joins international organization dedicated to COVID-19 vaccines

The flag of Finland was raised at the International Vaccine Institute (IVI) Headquarters today during a ceremony welcoming the country's accession to IVI.

11 Aug 2020

UTSW researchers show how vulnerable cells armor themselves against infection

Cells in some of the body's most vulnerable entry routes to bacterial infection buffer themselves when the immune system detects danger by reorganizing the cholesterol on their surfaces, a new study led by UTSW scientists suggests.

13 Apr 2020

A joint effort to confront the challenges of rising antimicrobial resistance in Asia

The International Vaccine Institute (IVI) and the Technical University of Denmark's (DTU) National Food Institute announced today a joint effort to strengthen external quality assurance programs for diagnostic laboratories in Asia to confront the challenges of rising antimicrobial resistance (AMR) in the region.

6 Mar 2020

"State of the Nation" report on STIs in England released

Two sexually transmitted infection (STI) charity organizations - British Association for Sexual Health and HIV and Terrance Higgins Trust have released a “State of The Nation” Report on STIs in England. This new report reveals the actual status of STIs in the nation and the steps that administration could take to bring down the numbers.

6 Feb 2020

Sida continues to support IVI’s mission to accelerate vaccine research

The International Vaccine Institute, a Seoul, Korea-based international organization, announced today that the Swedish International Cooperation Agency will continue to support IVI's mission to accelerate vaccine research and development for global health with a total contribution of SEK 50 million (approximately 5.24 million USD) over the next five years as part of a longstanding partnership between the Swedish government and IVI.

13 Jan 2020

UMSOM research shows even milder cases of diarrheal diseases can lead to child mortality

Diarrheal diseases are a leading cause of death for young children, accounting for nine percent of all deaths worldwide in children under five years of age, with most occurring in children under two years of age.

9 Jan 2020

Certain bacteria can override programmed cell death

Certain bacteria can override a defense mechanism of the immune system, so called programmed cell death, through inhibition of death effector molecules by their outer membranes components.

26 Dec 2019