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Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

Study uncovers inflammatory pathways that contribute to asthma flare-ups in children

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.

1 Aug 2025

Australian study uncovers first potential prophylactic treatment against HTLV-1

Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.

21 Jul 2025

Myeloid cells play central role in immune response after polytrauma

Gaining insights into the complex pathways and key cell populations involved in immune dysregulation can aid the development of therapeutic approaches to treat polytrauma, which is associated with poor patient outcomes.

21 Jul 2025

Boosting gut-friendly foods may slow biological aging, large US study finds

Higher scores on a dietary index linked to gut microbiota health are associated with slower biological aging in US adults, according to a large cross-sectional NHANES study. The findings suggest that improving diet quality for gut microbial diversity may help reduce age-related disease risk.

20 Jul 2025

New global guidelines aim to make clozapine safer and more accessible

The most effective antipsychotic drug for people with treatment-resistant schizophrenia is clozapine.

3 Jul 2025

Gene therapy brings back hearing in young and adult deaf patients

Gene therapy can improve hearing in children and adults with congenital deafness or severe hearing impairment, a new study involving researchers at Karolinska Institutet reports.

3 Jul 2025

Cannabis smoking changes your DNA, leaving epigenetic scars

Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic footprint on blood DNA. These methylation changes strongly overlap with those from tobacco and may serve as biomarkers of smoke exposure.

30 Jun 2025

IL-6 and CRP offer limited boost for predicting infections after lung cancer surgery

Early postoperative levels of IL-6 and CRP are independently associated with infection risk after pulmonary cancer surgery. However, adding these biomarkers to standard clinical predictors provides only limited improvement in infection prediction.

25 Jun 2025

First patient treated in international clinical trial for rare muscle-weakness disease

The first patient enrolled in a planned international clinical trial has been treated at HonorHealth Research Institute with a new type of immune therapy for those with a rare muscle-weakness disease known as Myasthenia Gravis.

16 Jun 2025

Biweekly chemotherapy dosing reduces toxicity in colorectal cancer patients

Patients with metastatic colorectal cancer who were treated with a biweekly dose of trifluridine-tipiracil (TAS-102) saw similar treatment effectiveness and reduced toxicity compared with treatment using standard dosing schedules, according to a recent study in The Oncologist that was co-authored by a Fox Chase Cancer Center physician.

6 Jun 2025

Two patients faced chemo. The one who survived demanded a test to see if it was safe.

JoEllen Zembruski-Ruple, while in the care of New York City's renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan. 29, her family members said. They didn't realize the drug could kill her.

4 Jun 2025

High-fiber plant-based diet could benefit patients at risk for developing multiple myeloma

Results from a new clinical trial suggest that a high-fiber plant-based diet could benefit patients at risk for developing multiple myeloma, the second most common type of blood cancer.

2 Jun 2025

Innovative technology simplifies T cell harvesting for cancer immunotherapy

CAR T cell immunotherapy, which uses a patient's own modified immune cells to find and destroy cancer cells, can produce dramatic results when treating blood cancers like lymphoma and leukemia and shows promise against solid tumors.

29 May 2025

Heavy smoking triggers systemic inflammation and vascular damage in new biomarker study

Heavy smoking in adult males significantly increases oxidative stress, inflammation, and vascular dysfunction, as shown by comprehensive blood and tissue biomarker analysis. The findings highlight measurable biological damage and reinforce the urgent need for targeted public health interventions.

26 May 2025

Study shows how daylight can boost the immune system's ability to fight infections

A breakthrough study, led by scientists at Waipapa Taumata Rau, University of Auckland, has uncovered how daylight can boost the immune system's ability to fight infections.

23 May 2025

Inhaled microplastics suppress pulmonary macrophages critical to the immune system

Microplastics are ubiquitous in the environment, and we all routinely inhale these tiny pollutants. Now new research published at the ATS 2025 International Conference has found that inhaled microplastics suppress pulmonary macrophages, a type of white blood cell found in the lungs that are critical to the immune system.

19 May 2025

HIV vaccine study marks breakthrough in targeting broad immune responses

A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus.

15 May 2025

Innovative technology offers non-invasive way to observe blood clotting

Researchers from the University of Tokyo have found a way to observe clotting activity in blood as it happens - without needing invasive procedures.