Antigen News and Research

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Docetaxel improves survival in men with high-grade prostate cancer and low PSA

Men with high-grade prostate cancer and low prostate-specific antigen (PSA) levels have a poor prognosis.

1 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

Next-generation vaccine candidates protect against multiple strains of influenza and last longer

Recent preclinical results indicate novel next-generation vaccine candidates developed at Cleveland Clinic protect against multiple strains of influenza and last longer than vaccines currently in use.

31 Oct 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

AI may help identify potential gonorrhea vaccine proteins

Gonorrhea, a sexually transmitted bacterial infection that affects more than 80 million people worldwide every year, has become resistant to almost all known antibiotics.

31 Oct 2023

Modular nanoparticles developed for targeted drug delivery and neutralizing biological agents

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

30 Oct 2023

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

Dendritic cells play a key role in the mammalian immune system. These cells are present throughout the human body and are known to capture foreign bodies, i.e., antigens, using extendable "arms" called dendrites.

30 Oct 2023

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Researchers found that SARS-CoV-2 antigens can persist in the body for up to 14 months after initial infection, challenging the idea that COVID-19 is a transient illness. This finding has implications for understanding long-term effects of the virus and could influence future treatments and vaccines.

30 Oct 2023

New ERC-funded research project aims to develop targeted treatments for chronic wounds and cancer

the Freiburg University Medical Center and member of the Medical Faculty at the University of Freiburg, has received a European Research Council (ERC) Starting Grant from the European Commission.

27 Oct 2023

New bioreactor could accelerate access to cancer-killing immunotherapy

A new tool to rapidly grow cancer-killing white blood cells could advance the availability of immunotherapy, a promising therapy which harnesses the power of the body's immune response to target cancer cells.

26 Oct 2023

Study finds racial disparities in receipt of low value health care

Older Black Americans are more likely to receive low value acute diagnostic tests than older White Americans, while older White Americans were more likely to receive low value screening tests and treatments, finds a study published by The BMJ today.

25 Oct 2023

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

The effects of vaccine booster doses on the adaptive evolution of the virus.

25 Oct 2023

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

The therapeutic potential of resveratrol, a red grape polyphenol.

25 Oct 2023

Researchers discover new way to trigger programmed cell death in cancer cells

A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.

24 Oct 2023

Resistant potato starch usage found to be feasible and safe for hematopoietic stem cell transplantation patients

The use of resistant potato starch (RPS), to modify gut microbial metabolism.

24 Oct 2023

NIH renews support for UMass Chan and UMass Lowell’s point-of-care technology initiative

UMass Chan Medical School and UMass Lowell have received an $8.9 million award from the National Institutes of Health (NIH) for renewed support of their initiative to advance the development of home-based and point-of-care health technologies.

19 Oct 2023

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Patients with multiple myeloma treated with idecabtagene vicleucel, known as "ide-cel," a chimeric antigen receptor (CAR) T-cell therapy, had no difference in overall survival outcomes regardless of race and ethnicity, according to a study published in Blood Advances.

19 Oct 2023

Early eating habits shape celiac disease risk in young kids, study shows

This long-term study reveals that dietary patterns in the first two years of life can significantly influence the risk of developing celiac disease autoimmunity (CDA) and celiac disease in genetically predisposed children. High intake of vegetable fats and milk at 9 months reduced CDA risk, while at 24 months, certain foods like wheat and vegetable fats increased the risk, emphasizing the role of non-gluten dietary factors.

17 Oct 2023

“Goblet cells” play an important role in the development of allergic conjunctivitis

The first step in the development of the allergic conjunctivitis is the penetration of the allergen through the epithelial layer.

17 Oct 2023

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

Antigen News and Research

Docetaxel improves survival in men with high-grade prostate cancer and low PSA

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Next-generation vaccine candidates protect against multiple strains of influenza and last longer

How next-gen sequencing is changing antibody drug discovery

AI may help identify potential gonorrhea vaccine proteins

Modular nanoparticles developed for targeted drug delivery and neutralizing biological agents

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

New ERC-funded research project aims to develop targeted treatments for chronic wounds and cancer

New bioreactor could accelerate access to cancer-killing immunotherapy

Study finds racial disparities in receipt of low value health care

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

Researchers discover new way to trigger programmed cell death in cancer cells

Resistant potato starch usage found to be feasible and safe for hematopoietic stem cell transplantation patients

NIH renews support for UMass Chan and UMass Lowell’s point-of-care technology initiative

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Early eating habits shape celiac disease risk in young kids, study shows

“Goblet cells” play an important role in the development of allergic conjunctivitis

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

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