Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Medicinal plant-derived compound destroys brain-eating amoeba in lab studies

Primary amoebic meningoencephalitis (PAM), a deadly disease caused by the "brain-eating amoeba" Naegleria fowleri, is becoming more common in some areas of the world, and it has no effective treatment.

13 Jan 2021

Synthetic lung organoids provide high-throughput platform to identify new cellular targets of SARS-CoV-2

An interesting new study published on the bioRxiv preprint server describes a new platform that allows a high-throughput workflow to generate matched human lung buds in the tens of thousands. This allows researchers to study SARS-CoV-2 infection and therapeutics in lung tissue that mirrors the key aspects of human lung development.

10 Jan 2021

Common gene expression changes at target tissues of four autoimmune diseases found

Autoimmune diseases are diseases of "mistaken identity", where the immune system - which is supposed to protect us against infectious diseases and neoplasias - mistakenly attacks and destroys components of our own body.

7 Jan 2021

Heat treatment during chemotherapy is more effective at destroying cancer cells

Heating up cancer cells while targeting them with chemotherapy is a highly effective way of killing them, according to a new study led by UCL researchers.

5 Jan 2021

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

A UT Southwestern research team has catalogued gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchene muscular dystrophy (DMD) in humans.

21 Dec 2020

Pioneering new eye test may predict wet AMD three years before symptoms develop

A pioneering new eye test, developed by scientists at UCL in collaboration with the Western Eye Hospital, London, may predict wet AMD, a leading cause of severe sight loss, three years before symptoms develop.

18 Dec 2020

University of Ottawa earns 10 Canada research chairs covering a broad scope of subjects

The University of Ottawa has earned a total of 10 Canada Research Chairs (CRCs) covering a broad scope of subjects, from the exploration of disruptive impacts of stress on higher brain functions to the need to preserve Indigenous traditional cultural memories, and emerging computing technologies that pave the way to smart cities.

18 Dec 2020

MFCR awards new grants to support an emerging approach to cancer therapeutics

The Mark Foundation for Cancer Research has awarded five new grants in support of an important, emerging approach to cancer therapeutics.

17 Dec 2020

Repair protein may prevent damage to healthy cells during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

9 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Adolescent competitive sport participation linked to better fitness at midlife in women

Females who participate in competitive sport during adolescence have better fitness at midlife than do females with no competitive sport background in adolescence, reveals a study conducted at the University of Jyväskylä.

7 Dec 2020

Novel modular design approach to antibody nanocage generation

A new study shows the benefits of using computational design to create antibody nanocages that have the required orientation.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD).

2 Dec 2020

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

Could the keto diet help prevent or mitigate severe COVID-19?

A new study published in the journal of Translational Medicine reports that the ketogenic diet (KD) may be useful in this area, with its track history of effectual reduction of fat mass, anti-inflammatory and immunomodulatory effects, and consequent improvement of cardiovascular health.

30 Nov 2020

Researchers study the role of viral intramembrane interactions in controlling programmed cell death

A research group from the Department of Biochemistry and Molecular Biology of the University of Valencia (UV), in coordination with the National Centre for Biotechnology (CNB) of the CSIC, has studied the role of the interactions within the membrane of proteins of viral families Herpesviridae and Poxviridae in the control of programmed cell death.

27 Nov 2020

Study unravels the immunogenicity of ferroptotic cancer cells

The interdisciplinary team of scientists from three different countries (Belgium, Italy, and Russia) under the leadership of Prof. Dr. Dmitri V. Krysko (Ghent University, Belgium) unravels the immunogenicity of ferroptotic cancer cells.

25 Nov 2020

Apoptosis News and Research

Medicinal plant-derived compound destroys brain-eating amoeba in lab studies

Synthetic lung organoids provide high-throughput platform to identify new cellular targets of SARS-CoV-2

Common gene expression changes at target tissues of four autoimmune diseases found

Heat treatment during chemotherapy is more effective at destroying cancer cells

Researchers use fruit fly model to understand COVID-19-related neurological complications

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

Pioneering new eye test may predict wet AMD three years before symptoms develop

University of Ottawa earns 10 Canada research chairs covering a broad scope of subjects

MFCR awards new grants to support an emerging approach to cancer therapeutics

Repair protein may prevent damage to healthy cells during cancer therapy

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

Study findings can guide personalized breast cancer therapies based on melatonin

Adolescent competitive sport participation linked to better fitness at midlife in women

Novel modular design approach to antibody nanocage generation

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

Could the keto diet help prevent or mitigate severe COVID-19?

Researchers study the role of viral intramembrane interactions in controlling programmed cell death

Study unravels the immunogenicity of ferroptotic cancer cells

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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