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GLP-1 drugs cut heart and kidney risks in type 1 diabetes study

In a large target trial emulation of 174,678 people with type 1 diabetes, GLP-1 receptor agonist initiation was associated with lower risks of major cardiovascular events and end-stage kidney disease over five years. The study also found no increased risk of hospitalization for diabetic ketoacidosis or severe hypoglycemia, supporting further randomized trials of GLP-1RAs as adjunctive therapy in type 1 diabetes.

22 Mar 2026

Study finds addiction risk tied to reward and impulse genes

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences – not from genes that specifically influence substance use disorder or any single drug.

22 Mar 2026

‘How low can you go?’ The shifting guidelines for blood pressure control

The patient initially came to see Mark Supiano in 2017 because her family was concerned about her short-term memory loss.

20 Mar 2026

Scientists reveal how light-activated drugs change receptor activity

Rendering a drug effective or ineffective in a flash at the appropriate location – this is the focus of research in photopharmacology.

19 Mar 2026

Study identifies protein biomarker and potential treatment for schizophrenia

Current schizophrenia medications treat symptoms such as hallucinations and delusions, but do little for cognitive symptoms like disorganized thinking or executive dysfunction.

19 Mar 2026

New wound dressing targets infections while reducing antibiotic overuse

Biomedical engineers from Brown University have developed a new wound dressing material that releases antibiotic drugs only when harmful bacteria are present in a wound.

19 Mar 2026

New tool helps identify fake medicines through pill dissolution patterns

Fake news can be tricky to spot, but spotting fake drugs just got a little easier. Researchers have devised a low-cost way to help distinguish legitimate medications from counterfeit ones.

19 Mar 2026

Brain lesions in Down syndrome show unexpected reversible changes

What has long been interpreted as permanent and irreversible vascular damage may not be exclusively so.

19 Mar 2026

How long should you take GLP-1 drugs? Study links longer use to lower heart risk

Continuous use of GLP-1 receptor agonists in adults with type 2 diabetes was associated with a lower risk of major cardiovascular events compared with sulfonylureas, with benefits increasing over time. Discontinuation or interruption was associated with a progressive loss of this protective effect, with risks approaching those of comparator therapy.

19 Mar 2026

Study explores if wastewater can track colorectal cancer at population level

A proof-of-concept study shows that cancer-linked RNA can be detected in wastewater, raising the possibility of tracking colorectal cancer patterns across communities without relying on individual screening.

19 Mar 2026

New compound targets the neuronal epigenome to treat Alzheimer's disease

A team from the University of Barcelona has designed and validated in animal models an innovative compound with a pioneering mechanism of action for the treatment of Alzheimer's disease.

19 Mar 2026

Python blood compound could lead to new weight loss therapies

University of Colorado Boulder researchers have discovered an appetite-suppressing compound in python blood that helps the snakes consume enormous meals and go months without eating yet remain metabolically healthy.

19 Mar 2026

Tumor debulking fails to improve survival in colorectal cancer

Research shows tumor debulking in advanced colorectal cancer does not enhance survival outcomes and may increase adverse effects, questioning its efficacy.

19 Mar 2026

Many ACA customers are paying higher premiums. Most blame Trump and Republicans, poll finds.

Most people who get their health coverage through the Affordable Care Act say they face sharply higher costs, with many worried they will have to pare back other expenses to cover them, according to a poll released Thursday.

19 Mar 2026

Blocking a single protein could make hidden HPV-positive tumors vulnerable to treatment

A team of scientists at Henry Ford Health + Michigan State University Health Sciences have uncovered a mechanism that allows certain head and neck cancers to hide from the immune system, a discovery that could change how some of the most treatment resistant tumors are approached.

18 Mar 2026

New pathway explains poor response to bladder cancer immunotherapy

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy.

18 Mar 2026

Stopping GLP-1 treatment linked to increase in risk of major cardiovascular events

Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular benefits.

18 Mar 2026

Precise application of radio waves could help counter neurological conditions

A new study found that precise application of radio waves can change the activity of brain cells in ways that could counter neurological conditions.

18 Mar 2026

Cancer cells rely on glutathione as fuel for growth

Researchers discovered an antioxidant, glutathione, that cancer cells appear to be "addicted to" as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient.

18 Mar 2026

Study finds GLP-1 medicines cut fat while preserving muscle function

Researchers found that GLP-1 medicines caused weight loss mainly through fat reduction, with only modest decreases in absolute muscle mass and no disproportionate loss of muscle function. In mice, physical performance improved, while in a small 12-week human pilot trial, strength was preserved despite reduced thigh muscle size.

18 Mar 2026