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SARS-CoV-2 accounted for 1 in 6 cases of sepsis during early months of the pandemic

SARS-CoV-2 accounted for 1 in 6 cases of sepsis during the first 33 months of the COVID-19 pandemic, highlighting the importance of viral sepsis, according to a new study led by researchers at the Harvard Pilgrim Health Care Institute.

29 Sep 2023

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

A groundbreaking development in biomedical engineering has led to the creation of a human stomach micro-physiological system (hsMPS), representing a significant leap forward in understanding and treating various gastrointestinal diseases, including stomach cancer.

28 Sep 2023

Researchers develop new way to boost immune cells' ability to fight TB

Tuberculosis is old - ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn't been cured yet.

27 Sep 2023

UKHSA donates advanced genomic surveillance equipment to CARPHA

This is a significant stride towards strengthening global genomic surveillance to track new variants and pathogens of pandemic and epidemic potential.

27 Sep 2023

Promising potential of probiotics and their byproducts for targeting antibiotic-resistant bacteria

The use of probiotics and antimicrobial peptides (AMPs) against multi-drug-resistant (MDR) bacteria.

27 Sep 2023

Unions between close relatives may increase the risk of common diseases, study finds

A new study finds that consanguinity – unions between close relatives - may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD).

26 Sep 2023

Monkeypox mimics smallpox vaccine's immune response, new study reveals

The study in Nature Communications reveals that MPOX infection triggers an anti-viral antibody response akin to that from smallpox vaccination. Utilizing a comprehensive array of ELISAs, scientists found a high level of specificity and sensitivity in detecting antibodies against both MPOX and smallpox, offering a new, accurate way to measure immune responses.

26 Sep 2023

Study reveals how a tiny strand of RNA controls T-cell memory to recognize tumors

A team of researchers at the University of Massachusetts Amherst has shown that a single, small strand of microRNA, or miRNA, known as let-7, governs the ability of T-cells to recognize and remember tumor cells.

25 Sep 2023

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

After world's first successful transplant in 2022, also performed at the University of Maryland Medical Center (UMMC), this groundbreaking transplant team performed second pig heart transplant on patient deemed ineligible for traditional heart transplant.

25 Sep 2023

Cellular crosstalk between mother and offspring is more complex than expected

Scientists have known for decades that pregnancy requires a mother's body to adjust so that her immune system does not attack the growing fetus as if it were a hostile foreign invader.

22 Sep 2023

Omics analysis identifies new biomarkers for predicting mortality in patients with pneumonia

Community-acquired pneumonia (CAP) is a major infectious disease worldwide and contributes to high mortality and massive economic burden. Hospital mortality among the severe CAP (SCAP) remains high, ranging from 25% to more than 50%.

22 Sep 2023

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

A clinical trial has launched to test whether early intensive immune modulation for hospitalized COVID-19 patients with relatively mild illness is beneficial.

22 Sep 2023

Nanoparticle vaccine may offer safe and effective protection against Dabie Bandavirus

Cleveland Clinic researchers have used nanoparticles to develop a potential vaccine candidate against Dabie Bandavirus, formerly known as Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV), a tick-borne virus that currently has no prevention, treatment or cure.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Mount Sinai secures $6.2 million grant to expand the Cohen Center for Recovery From Complex Chronic Illnesses

Mount Sinai's Department of Rehabilitation and Human Performance has announced a $6.2 million grant from the Steven & Alexandra Cohen Foundation.

20 Sep 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Health workers warn loosening mask advice in hospitals would harm patients and providers

Nurses, researchers, and workplace safety officers worry new guidelines from the Centers for Disease Control and Prevention might reduce protection against the coronavirus and other airborne pathogens in hospitals.

18 Sep 2023

Bacteriophage cocktail can effectively disrupt Klebsiella pneumoniae biofilms on medical equipment

Researchers investigated whether a cocktail of bacteriophages coding for the depolymerase polysaccharide could effectively disrupt Klebsiella pneumoniae biofilms.

18 Sep 2023

Klebsiella: Emerging multidrug-resistant and hypervirulent threats to health

Announcing a new article publication for Zoonoses journal. Members of the genus, Klebsiella, are becoming increasingly challenging to control due to the recent convergence of multidrug-resistant (MDR) and hypervirulent (hv) phenotypes in some species of concern to One Health.

15 Sep 2023

Pathogen News and Research

SARS-CoV-2 accounted for 1 in 6 cases of sepsis during early months of the pandemic

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

Researchers develop new way to boost immune cells' ability to fight TB

UKHSA donates advanced genomic surveillance equipment to CARPHA

Promising potential of probiotics and their byproducts for targeting antibiotic-resistant bacteria

Unions between close relatives may increase the risk of common diseases, study finds

Monkeypox mimics smallpox vaccine's immune response, new study reveals

Study reveals how a tiny strand of RNA controls T-cell memory to recognize tumors

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

Cellular crosstalk between mother and offspring is more complex than expected

Omics analysis identifies new biomarkers for predicting mortality in patients with pneumonia

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

Nanoparticle vaccine may offer safe and effective protection against Dabie Bandavirus

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Mount Sinai secures $6.2 million grant to expand the Cohen Center for Recovery From Complex Chronic Illnesses

Transforming postpartum depression treatment with neurosteroids

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Health workers warn loosening mask advice in hospitals would harm patients and providers

Bacteriophage cocktail can effectively disrupt Klebsiella pneumoniae biofilms on medical equipment

Klebsiella: Emerging multidrug-resistant and hypervirulent threats to health

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