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Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Indiana University School of Medicine researchers have identified a promising new combination of drugs to treat juvenile myelomonocytic leukemia (JMML), a rare form of blood cancer that affects children.

5 Apr 2023

Penn State Health expert debunks six myths about organ donation

Right now, more than 100,000 people in the U.S. - nearly two times the population of Harrisburg - are waiting for organ transplants.

5 Apr 2023

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease - about a half million people in the United States alone suffer from the condition.

4 Apr 2023

A doctor’s love letter to ‘the people’s hospital’

Could a charity hospital founded by a crusading Dutch playwright, a group of Quakers, and a judge working undercover become a model for the U.S. health care system? In this episode of the podcast "An Arm and a Leg," host Dan Weissmann speaks with Dr. Ricardo Nuila to find out.

3 Apr 2023

AI chatbot may help improve health outcomes for patients with cirrhosis and liver cancer

A new study by Cedars-Sinai investigators describes how ChatGPT, an artificial intelligence (AI) chatbot, may help improve health outcomes for patients with cirrhosis and liver cancer by providing easy-to-understand information about basic knowledge, lifestyle and treatments for these conditions.

31 Mar 2023

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation - the transplantation of living cells, tissues and organs from one species to another - two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.

29 Mar 2023

Two distinct subtypes of insulin-producing beta cells identified

A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 and Type 2 diabetes.

28 Mar 2023

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

The National Institute of Allergy and Infectious Diseases awarded an up to $16 million contract to Tulane University to bring to phase one clinical trial a nasal spray vaccine university researchers invented to thwart antibiotic-resistant Klebsiella pneumoniae, a leading cause of pneumonia.

24 Mar 2023

UW researchers identify a target that may make bone marrow transplants safer and more effective

A bone marrow transplant can be a lifesaving treatment for people with relapsed blood cancers, but a potentially lethal complication known as graft-versus-host disease put limitations on this procedure.

24 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Loss of a beta cell subset might contribute to type 2 diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy.

13 Mar 2023

Study: Black patients with pulmonary fibrosis are younger than Hispanic and white counterparts

Pulmonary fibrosis is a devastating disease characterized by progressive scarring in the lungs, killing up to half of patients within five years of a diagnosis.

10 Mar 2023

Insulin deficiency leads to reduced pancreas size in type 1 diabetes

Individuals with Type 1 diabetes have a smaller pancreas than people without diabetes. This is surprising because insulin-producing beta cells account for just a small fraction of the pancreas, so the loss of beta cells in Type 1 diabetes would not be expected to reduce pancreas size.

10 Mar 2023

Scientists identify the cause of leukemia in people with trisomy 21

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer.

10 Mar 2023

Montana considers new wave of legislation to loosen vaccination rules

When Deb Horning's youngest daughter was 5, she got her measles, mumps, and rubella shot like many other kindergartners. But unlike many other moms, Horning had to stay away from her daughter for a week after the shot.

10 Mar 2023

Researchers receive PCORI funding to study the effectiveness of individualized model of hemodialysis

The Patient-Centered Outcomes Research Institute (PCORI) recently awarded researchers at Wake Forest University School of Medicine $10.2 million to study the effectiveness of an individualized model of hemodialysis, a procedure in which the blood is cleaned by a dialysis machine.

9 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and safe for use in humans, scientists must first precisely understand on the cellular and molecular levels which factors are necessary for implanted stem-cell derived heart cells to properly grow and integrate in three dimensions within surrounding tissue.

8 Mar 2023

FDA mandate to limit the dosage of acetaminophen linked to reductions in serious liver injury

A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver injury, according to a study led by investigators at the University of Alabama and Weill Cornell Medicine.

7 Mar 2023

Transplant News and Research

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Penn State Health expert debunks six myths about organ donation

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

A doctor’s love letter to ‘the people’s hospital’

AI chatbot may help improve health outcomes for patients with cirrhosis and liver cancer

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

Two distinct subtypes of insulin-producing beta cells identified

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

UW researchers identify a target that may make bone marrow transplants safer and more effective

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

Loss of a beta cell subset might contribute to type 2 diabetes

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Study: Black patients with pulmonary fibrosis are younger than Hispanic and white counterparts

Insulin deficiency leads to reduced pancreas size in type 1 diabetes

Scientists identify the cause of leukemia in people with trisomy 21

Montana considers new wave of legislation to loosen vaccination rules

Researchers receive PCORI funding to study the effectiveness of individualized model of hemodialysis

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

FDA mandate to limit the dosage of acetaminophen linked to reductions in serious liver injury

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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