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New Alzheimer's guidelines provide comprehensive framework for diagnosis

We have entered a new era of improved and emerging biologically-based diagnostic biomarkers for Alzheimer's disease (AD) and AD-related neurodegenerative disorders (ADRD) that are rapidly impacting evaluation and care paradigms in every clinical setting: primary care, specialty care and dementia subspecialty care.

23 Dec 2024

Healthy lifestyles linked to younger brains

Using an AI tool, researchers at Karolinska Institutet have analyzed brain images from 70-year-olds and estimated their brains' biological age.

20 Dec 2024

Vanderbilt researchers achieve milestone in Alzheimer's drug development

Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ascending dose clinical trial of VU319, a drug for memory loss in people with Alzheimer's disease and schizophrenia.

19 Dec 2024

Study shines new light on guidelines for delivery timing in women with chronic hypertension

A collaborative study from physician researchers at the University of Cincinnati College of Medicine is shining new light on current guidelines for delivery timing in pregnant mothers with chronic hypertension.

19 Dec 2024

New blood test could help identify patients at risk for cognitive impairment

To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate "downstream" biological markers – those at the end of a cascade of events.

19 Dec 2024

Free cholesterol in HDL linked to increased cardiovascular disease risk

Houston Methodist researchers have discovered that certain components of so-called "good" cholesterol -- high-density lipoproteins (HDL) – may be associated with an increased prevalence of cardiovascular disease.

19 Dec 2024

Reduced blood thinner dose may lower bleeding risk and hospital visits

For people taking popular blood thinners after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospital visits, a Michigan Medicine-led study suggests.

19 Dec 2024

The role of phytochemicals in combating metabolic diseases

This editorial reviews the impact of phytochemicals on metabolic diseases, emphasizing their potential in reducing inflammation and improving health outcomes.

19 Dec 2024

Researchers receive NIH grant to study dementia caused by cerebral small vessel disease

Researchers at Washington University School of Medicine in St. Louis have been awarded $7.5 million from the National Institutes of Health (NIH) to investigate a form of dementia caused by cerebral small vessel disease, the second-leading cause of dementia after Alzheimer's disease.

17 Dec 2024

A comprehensive review of atrial fibrillation

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime.

17 Dec 2024

Researchers uncover key mechanisms in blood vessel formation

The formation of blood vessels is a complex process involving the interplay of proteins and mechanic forces.

17 Dec 2024

CNIC team develops a comprehensive set of genetic tools and mouse lines

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the study of gene function and its implications in health and disease.

14 Dec 2024

Potential new mRNA-based therapy for pre-eclampsia

Lipid nanoparticles targeting VEGF mRNA show promise in treating pre-eclampsia, restoring maternal blood pressure and enhancing fetal health in murine models.

13 Dec 2024

Portable MRI and AI improve Alzheimer’s diagnosis with cost-effective precision

Researchers optimized portable low-field MRI with machine learning to improve brain morphometry and white matter hyperintensity detection, making Alzheimer's diagnosis more accessible and cost-effective.

12 Dec 2024

Circadian chaos: How transportation noise harms heart health

Transportation noise poses serious risks to cardiovascular health, causing inflammation, oxidative stress, and circadian rhythm disruption, with compounded effects from air pollution.

12 Dec 2024

Controversy surrounds landmark anti-platelet drug trial

An investigation published by The BMJ today raises new concerns over the landmark clinical trial (PLATO) that was used to gain worldwide approval for the anti-platelet drug ticagrelor (Brilinta in the US and Brilique in Europe), manufactured by AstraZeneca.

11 Dec 2024

Early smoking causes structural and functional heart damage

Cigarette smoking from childhood into early adulthood is associated with an increased risk of premature cardiac injury, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

11 Dec 2024

Low magnesium intake identified as a key factor in cardiovascular disease

Inadequate magnesium intake is a critical factor in cardiovascular disease development, necessitating increased awareness and dietary improvements.

11 Dec 2024

UVM scientists discover new mechanism for blood flow regulation in the brain

A team of UVM scientists led by Mark Nelson, Ph.D., from the Larner College of Medicine at the University of Vermont, has uncovered a novel mechanism that reshapes our understanding of how blood flow is regulated in the brain.

9 Dec 2024

Study identifies potential risk factor for aortic aneurysms in Loeys-Dietz syndrome

Studying the cells of people and genetically engineered mice, Johns Hopkins Medicine scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, are especially prone to developing aneurysms at the root of the aorta, the major artery that carries blood away from the heart and to the rest of the body.

9 Dec 2024