Inflammation News and Research

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Hepatitis C virus co-opts an immune protein to evade antiviral defenses

By discovering a trick the hepatitis C virus uses to evade the immune system, scientists have identified a new antiviral defense system that could be used to treat many virus infections, according to new research published today in eLife.

16 Jun 2020

TERAVOLT tracks outcomes of people with thoracic cancers affected by COVID-19

New data from TERAVOLT, a global consortium that tracks outcomes of people with thoracic cancers affected by COVID-19, offers clues as to why they experienced a high death rate of 33% when the coronavirus swept across Europe.

16 Jun 2020

Researchers create superior bone grafts using primitive stem cells

Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting.

16 Jun 2020

Exposure to certain e-cig cartridges may cause fatal lung damage

Researchers at the University of Rochester Medical Center, New York, have shown that long-term exposure to certain electronic nicotine delivery systems (ENDS) may cause lung toxicity and injury among vapers.

16 Jun 2020

Abnormal expression of Zeb2 protein in epithelial cells can induce colorectal cancer

A collaborative study by research groups from the VIB-UGent Center for Inflammation Research and Ghent University uncovered a new mechanism causing colorectal cancer.

16 Jun 2020

Life saving drug found for COVID-19 patients on ventilators

Results from Oxford University’s RECOVERY trial into existing drugs for the treatment of COVID-19 has found that dexamethasone reduced deaths by a third in ventilated coronavirus patients and by a fifth in coronavirus patients requiring oxygen. This is the first drug of its kind to be demonstrated to have a significant impact on COVID-19 mortality.

16 Jun 2020

Blood vessels can sense the metabolic state of neighboring neural cells, shows study

The brain is our most energy-hungry and metabolically active organ. It is responsible for our thoughts, ideas, movement and ability to learn.

16 Jun 2020

Inhaled steroids reduce ACE2 expression in COPD lungs

A new study by scientists at Imperial College London, University of Newcastle and Prokarium, and published on the preprint server bioRxiv* in June 2020 examines the role played by inhaled corticosteroids (ICS) in the risk of acquisition of COVID-19 infection by COPD patients.

15 Jun 2020

Irregular circadian rhythm in older adults associated with increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

15 Jun 2020

GLP-1-based medicine for diabetic patients does not cause pancreatitis

About 50,000 Danish diabetic patients are treated with GLP-1-based medicine. GLP-1 is a hormone that reduces the blood sugar and inhibits the appetite, and it is a frequent treatment for type 2 diabetes and obesity.

15 Jun 2020

New nonsurgical treatment reduces pain, improves function in patients with "frozen shoulder"

A new nonsurgical treatment decreases errant blood flow in the shoulder to quickly reduce pain and improve function in patients with adhesive capsulitis, also known as "frozen shoulder,"

15 Jun 2020

RCSI scientists develop new biomaterial with potential to accelerate bone regeneration

Scientists at RCSI University of Medicine and Health Sciences have developed a new biomaterial that has the potential to accelerate bone regeneration by promoting an immune response that encourages repair and lowers the risk of inflammation.

12 Jun 2020

Does COVID-19 injure the placenta of pregnant women?

News-Medical speaks to Dr. Jeffery Goldstein about whether COVID-19 is damaging the placentas of pregnant women and what women can do to protect themselves.

12 Jun 2020

Type III interferons can increase risk of bacterial "superinfections" in the lung, research shows

Interferons and other cytokines produced by the immune system are important defenses against viral infections, but as we have seen in COVID-19, they can also contribute to damaging, potentially life-threatening lung inflammation.

12 Jun 2020

Engineered natural killer cells show promise for treating a form of leukemia

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells - a type of immune cell - with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

12 Jun 2020

Progression and severity of COVID-19 highly dependant on cytokine changes

A new review paper by the researchers from Spain, published in the journal Cytokine & Growth Factor Reviews, demonstrates how changes in the levels of cytokines and other biomolecules are associated with the presence and more serious prognosis of coronavirus disease (COVID-19).

11 Jun 2020

COVID-19 poses a global threat to the entire nervous system

A new review of neurological symptoms of COVID-19 patients in current scientific literature reveals the disease poses a global threat to the entire nervous system, reports a Northwestern Medicine study published this week in Annals of Neurology.

11 Jun 2020

Novel immunotherapy-plus-chemotherapy combo for pleural mesothelioma shows promise

Inoperable malignant pleural mesothelioma, is a rare and aggressive cancer of the protective lining of the lungs, or pleura, often caused by exposure to asbestos.

11 Jun 2020

Race-related differences in genetic determinants of COVID-19 severity

Researchers at the University of Iowa have identified differences in gene expression levels between African Americans and European Americans that may explain the disproportionately higher rates of coronavirus disease 2019 (COVID-19) cases and related deaths among African Americans.

11 Jun 2020

Nutritional study shows wide range of metabolic responses after eating in healthy adults

Researchers led by King's College London announced today the first published results from PREDICT, the largest ongoing nutritional study of its kind.

11 Jun 2020

Inflammation News and Research

Hepatitis C virus co-opts an immune protein to evade antiviral defenses

TERAVOLT tracks outcomes of people with thoracic cancers affected by COVID-19

Researchers create superior bone grafts using primitive stem cells

Exposure to certain e-cig cartridges may cause fatal lung damage

Abnormal expression of Zeb2 protein in epithelial cells can induce colorectal cancer

Life saving drug found for COVID-19 patients on ventilators

Blood vessels can sense the metabolic state of neighboring neural cells, shows study

Inhaled steroids reduce ACE2 expression in COPD lungs

Irregular circadian rhythm in older adults associated with increased risk of Parkinson's disease

GLP-1-based medicine for diabetic patients does not cause pancreatitis

New nonsurgical treatment reduces pain, improves function in patients with "frozen shoulder"

RCSI scientists develop new biomaterial with potential to accelerate bone regeneration

Does COVID-19 injure the placenta of pregnant women?

Type III interferons can increase risk of bacterial "superinfections" in the lung, research shows

Engineered natural killer cells show promise for treating a form of leukemia

Progression and severity of COVID-19 highly dependant on cytokine changes

COVID-19 poses a global threat to the entire nervous system

Novel immunotherapy-plus-chemotherapy combo for pleural mesothelioma shows promise

Race-related differences in genetic determinants of COVID-19 severity

Nutritional study shows wide range of metabolic responses after eating in healthy adults

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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