Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Analysis of diabetes drugs

Most oral medications prescribed for type 2 diabetes are similarly effective for reducing blood glucose, but the drug metformin is less likely to cause weight gain and may be more likely than other treatments to decrease so-called bad cholesterol, according to a report funded by HHS Agency for Healthcare Research and Quality.

17 Jul 2007

Bak protein's deadly double whammy

When a cell is seriously stressed, say by a heart attack, stroke or cancer, a protein called Bak just may set it up for suicide, researchers have found.

13 Jul 2007

Contaminated toothpaste now in the UK

Contaminated toothpaste has now found it's way into the UK. Fake Sensodyne toothpaste which contains traces of toxic chemicals is being sold in markets, discount shops and car boot sales.

12 Jul 2007

Functional data analysis in renal anemia

Anemia is one of the most frequent complications of hemodialysis, and its correction is an important factor in restoring a tolerable quality of life to dialysis-dependent patients.

12 Jul 2007

First mouse model of lung transplantation

Lung transplants have been performed successfully for more than 20 years in humans but never before in mice – until now.

12 Jul 2007

Obesity rate in the U.S. has increased at an alarming rate over the past three decades

The U.S. obesity prevalence increased from 13 percent to 32 percent between the 1960s and 2004, according to researchers at the Johns Hopkins Bloomberg School of Public Health Center for Human Nutrition.

11 Jul 2007

First-time link between food intolerance and illness

Researchers from University College London have found compelling evidence for the first time to link food intolerances and serious illness.

11 Jul 2007

Neutral genetic drift

Johns Hopkins researchers have added to the growing mound of evidence that many of the genetic bits and pieces that drive evolutionary changes do not confer any advantages or disadvantages to humans or other animals.

10 Jul 2007

Why males show a higher rate of inflammation than females in the same diseases

Production of a protein that promotes inflammation appears to be linked to the higher incidence of liver cancer in men than in women, researchers at the University of California, San Diego (UCSD) School of Medicine have determined in mouse studies.

9 Jul 2007

Study targets pharmacists to help diabetes sufferers

A new Wesley Research Institute project aims to make it much easier for people to manager their Type 2 Diabetes by using community pharmacists.

9 Jul 2007

University Jaume I patents fluorescent sensor

The University Jaume I (UJI) has patented a new fluorescent chemical sensor that is capable of detecting citric acid at low concentrations more rapidly and cheaply than the current optical sensors.

9 Jul 2007

Cancer risk in HIV, transplant patients

HIV/AIDS and kidney transplant patients are at much greater risk of contracting 20 different types of cancer than the general population, according to a land mark paper in The Lancet.

8 Jul 2007

Gene found that protects from serious kidney disease

A combination of mice and patient studies sheds light on cause and possible new therapies of kidney diseases.

8 Jul 2007

More alerts over Chinese made products

Canadian and U.S. authorities have issued warnings to consumers regarding Chinese-made counterfeit toothpaste after more tainted products have been discovered in stores.

8 Jul 2007

Live donors have genuine concerns with insurance problems

According to a new review in American Journal of Transplantation, people who donate their kidney or part of their liver to help someone else may themselves encounter difficulty with life and health insurance, despite insurance companies saying otherwise.

4 Jul 2007

Biomira files NDA for novel inhibitor of hypoxia-inducible factor-1 alpha

Biomira Inc. has announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for PX-478. PX-478 has been shown in preclinical studies to inhibit hypoxia-inducible factor (HIF)-1 alpha, a protein that controls the transcription of a number of genes whose products are important for tumor growth and survival.

4 Jul 2007

Canadians warned about tainted and fake toothpaste

Canadians are being warned about a counterfeit toothpaste on sale in stores which contains harmful ingredients.

2 Jul 2007

Link between ciliary signaling and cancer

Submarines have periscopes. Insects have antennae. And increasingly, biologists are finding that most normal vertebrate cells have cilia, small hair-like structures that protrude like antennae into the surrounding environment to detect signals that control cell growth.

29 Jun 2007

Inhaled insulin for the treatment of type 2 diabetes

Inhaled insulin, taken before meals, can improve blood glucose control for people with type 2 diabetes who have not had good results with short-acting injected insulin that is taken in addition to the baseline insulin administered throughout the day and night, according to a new review of the body of published research.

29 Jun 2007

Bayer and Onyx submit supplemental NDA for Nexavar

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals have announced that a Supplemental New Drug Application (sNDA) for Nexavar (sorafenib) tablets has been submitted to the U.S. Food and Drug Administration (FDA) for the treatment of patients with hepatocellular carcinoma (HCC), the most common form of liver cancer. Nexavar is currently approved in more than 50 countries for the treatment of advanced kidney cancer.

28 Jun 2007