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'Brain bleeds' in infants can affect visual outcomes at the end of their primary school years

Severe "brain bleeds" experienced by some babies in the first year following their birth lead to long-term sight problems, researchers at the University of Bristol, UKhave found as part of a ten-year follow-up study.

23 Jun 2022

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Results of a study of molecular tumor profiling in young patients revealed a high rate of genetic alterations with potential for impacting clinical care, including clarifying diagnoses and treatment with matched, precision cancer drugs.

23 Jun 2022

"Scarless" tracheal shave can provide optimal care for people receiving gender-affirming surgery

Doctors at the UCLA Gender Health Program have developed a technique to reduce an Adam's apple bump without leaving a scar on the patient's neck.

22 Jun 2022

Lung cancer patients treated with immune checkpoint inhibitors can be safely vaccinated against COVID-19, study says

Cancer patients have received priority status to receive COVID-19 vaccinations but there is limited data regarding the safety and efficacy of the vaccines for patients treated for lung cancer with immune checkpoint inhibitors.

22 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

New weight loss treatment is marked by heavy marketing and modest results

First came the "edible billboard," which appeared last year during the holidays in New York's East Village loaded with cake treats. Then, in late January, came the national marketing campaign, with TV and digital media promoting the idea that trying to lose weight doesn't mean a person can't enjoy eating.

22 Jun 2022

New technology can revitalize the bactericidal effects of conventional antibiotics in MDR E.coli infections

A research team led by Professor Kelvin Yeung Wai-kwok from the Department of Orthopaedics and Traumatology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) has designed a non-invasive technology to revitalize the bactericidal effects of conventional antibiotics in multidrug-resistant (MDR)Escherichia coli (E. coli)-associated deep tissue infections, such as urinary tract and peritoneal infections.

22 Jun 2022

Potential SARS-CoV-2 antivirals based on host miRNAs

A recent research paper posted to the bioRxiv* preprint server demonstrated micro ribonucleic acids (miRNAs) as potential antiviral options against various coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

21 Jun 2022

Medical societies publish guidelines on how to treat pre-invasive lesions of the vulva

Four international medical societies have collaborated on consensus statements for physicians, published in the Journal of Lower Genital Tract Disease, about how to treat pre-invasive lesions of the vulva.

21 Jun 2022

Simplicity is key when it comes to ablation, global AFib study finds

Results from one of the largest global studies of atrial fibrillation (AFib) procedures show that the simple approach is usually best when it comes to ablation, a procedure where physicians destroy or ablate cardiac tissue to correct irregular heart rhythms.

21 Jun 2022

Breast cancer trial results may not translate to real-world outcomes based on treatment discontinuation

New research in the June 2022 issue of JNCCN - Journal of the National Comprehensive Cancer Network raises issues with clinical trial findings that show adjuvant hormone therapy (AHT)-related hot flashes predict better outcomes for estrogen receptor-positive (ER+) breast cancer.

21 Jun 2022

New screening tool could increase the number of tests on solid tumor sample by up to 50 times

A screening tool developed at the University of Strathclyde, UK, could increase the number of tests on a solid tumor sample by up to 50 times.

21 Jun 2022

Wistar scientists discover a new way to boost a person's immune response to tumors

Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

21 Jun 2022

TB-causing bacteria can evolve rapidly in response to new environments, study says

Researchers have identified how the bacterium that causes tuberculosis (TB) can evolve rapidly in response to new environments, says a study published today in eLife.

21 Jun 2022

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

A new study reported four cases of Myelin Oligodendrocyte Glycoprotein-Associated Disorder that commenced after SARS-CoV-2 infection.

21 Jun 2022

After maternal COVID vaccination, infants have persistent anti-SARS-CoV-2 antibodies at 3 months

A recent article published in the journal Clinical Infectious Diseases assessed the kinetics of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies derived from mothers among infants in association with the timing of prenatal SARS-CoV-2 vaccination.

21 Jun 2022

Real-world study shows Paxlovid associated with lower hospitalization rates

In a recent study posted to the medRxiv* pre-print server, researchers investigated the effectiveness of nirmatrelvir plus ritonavir in preventing hospitalizations among individuals aged 50 or older and vaccinated for coronavirus disease 2019 (COVID-19).

20 Jun 2022

Researchers highlight the impact of macrophage subtypes on acute kidney injury to CKD transition

Acute kidney injury (AKI) is a condition in which kidneys are unable to filter waste from the blood effectively, leading to various health complications.

20 Jun 2022

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

In this new article publication from Acta Pharmaceutica Sinica B, authors Yun Yang, Danrong Hu, Yi Lu, Bingyang Chu, Xinlong He, Yu Chen, Yao Xiao, Chengli Yang, Kai Zhou, Liping Yuan and Zhiyong Qian from Sichuan University, Chengdu discuss tumor-targeted/reduction-triggered composite multifunctional nanoparticles for breast cancer chemo-photothermal combinational therapy.

18 Jun 2022

Study points to a new direction for the development of NAMPT-targeted cancer therapies

In this new article publication from Acta Pharmaceutica Sinica B, authors Ying Wu, Congying Pu, Yixian Fu, Guoqiang Dong, Min Huang and Chunquan Sheng from Second Military Medical University, Shanghai, China and University of Chinese Academy of Sciences, Shanghai, China discuss how NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion.

18 Jun 2022

Therapy News and Research

'Brain bleeds' in infants can affect visual outcomes at the end of their primary school years

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

"Scarless" tracheal shave can provide optimal care for people receiving gender-affirming surgery

Lung cancer patients treated with immune checkpoint inhibitors can be safely vaccinated against COVID-19, study says

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

New weight loss treatment is marked by heavy marketing and modest results

New technology can revitalize the bactericidal effects of conventional antibiotics in MDR E.coli infections

Potential SARS-CoV-2 antivirals based on host miRNAs

Medical societies publish guidelines on how to treat pre-invasive lesions of the vulva

Simplicity is key when it comes to ablation, global AFib study finds

Breast cancer trial results may not translate to real-world outcomes based on treatment discontinuation

New screening tool could increase the number of tests on solid tumor sample by up to 50 times

Wistar scientists discover a new way to boost a person's immune response to tumors

TB-causing bacteria can evolve rapidly in response to new environments, study says

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

After maternal COVID vaccination, infants have persistent anti-SARS-CoV-2 antibodies at 3 months

Real-world study shows Paxlovid associated with lower hospitalization rates

Researchers highlight the impact of macrophage subtypes on acute kidney injury to CKD transition

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

Study points to a new direction for the development of NAMPT-targeted cancer therapies

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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