Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Molecule found in liver cells could explain a lot about the relationship between diet, lipid levels in blood, and atherosclerosis

A team of researchers at the University of Pennsylvania School of Medicine have made a discovery that a molecule found in liver cells is important in explaining the relationship between diet, lipid levels in blood, and atherosclerosis.

15 May 2005

Tamoxifen study counters hopes that drug might protect the heart

Despite previous studies hinting at tamoxifen's potential benefit for breast cancer survivors' heart health, California researchers have found that the breast cancer drug does not decrease survivors' risk of heart attack.

15 May 2005

Statin therapy is cost-effective for a wider range of individuals with vascular disease or diabetes than previously recognised

Current guidelines generally recommend the initiation of statin therapy when the estimated 10-year risk of a non-fatal heart attack or coronary death is at least 15-20%.

12 May 2005

Fat-fighting drugs may be a far riskier business than they seem

Experts are warning that despite the fact that obesity is one of the biggest preventable causes of death, fat-fighting drugs may be a far riskier business than they seem, particularly for investors.

11 May 2005

Targeted Genetics announces new patent for Hyperlipidemia

Targeted Genetics Corporation announced today issuance of U.S. patent #6,887,463, entitled, "Methods and Compositions for Gene Therapy for the Treatment of Defects in Lipoprotein Metabolism."

11 May 2005

Healthy dose of fat is needed for a healthy metabolism

Just when we had all been convinced by information from just about every quarter, that fat was the bad guy of the diet kingdom, new research has found that a healthy dose of fat is needed for a healthy metabolism.

11 May 2005

Drug lowers inflammatory markers associated with risk for heart attack

A preliminary study suggests that use of a drug that inhibits a specific protein in patients with certain genetic variants that increase their risk for heart attack reduced their levels of inflammatory markers associated with heart attack risk, according to a study in the May 11 issue of JAMA.

10 May 2005

Polypill improves survival rates for heart disease sufferers

A ‘polypill’ made up of a combination of drugs could extend the lives of thousands of patients with coronary heart disease, say researchers at The University of Nottingham.

10 May 2005

Expert analyzes why manufacturers have gradually abandoned vaccines

Recent shortages of vaccines, most recently the flu vaccine during the past winter, are not short-term glitches--they reflect long-term problems in the vaccine industry. A variety of social, legal and economic forces have caused pharmaceutical companies to withdraw their commitment to vaccines, according to pediatrician and vaccine expert Paul A. Offit, M.D., chief of Infectious Diseases at The Children's Hospital of Philadelphia.

10 May 2005

New study suggests Pioglitazone HCl may significantly improve key predictors of cardiovascular risk

Study results published in the May 17th issue of Circulation, the journal of the American Heart Association, found that the diabetes medication pioglitazone HCl reduced carotid artery intima-media thickness (IMT). Patients taking pioglitazone also experienced significant reductions in insulin resistance, C-reactive protein (a marker for inflammation) and blood pressure, all of which contribute to the overall risk for cardiovascular disease.

9 May 2005

New fat is needed to clear old fat from the system

Where fat comes from determines whether the body can metabolize it effectively. Researchers at Washington University School of Medicine in St. Louis have found that the "old" fat stored in the body's peripheral tissues -- that is, around the belly, thighs or bottom -- can't be burned efficiently unless "new" fat is eaten in the diet or made in the liver.

9 May 2005

Metabolic syndrome costing four times that for all other patients

It is well known that hypertension, diabetes, and obesity are each taking a toll on Americans' health, but according to a new analysis, metabolic syndrome, a condition characterized by a combination of these and/or other risk factors, is fast becoming one of the nation's costliest health concerns.

9 May 2005

Nutritious cranberries good for the heart as well

Researchers say that cranberries improve the health of pigs’ hearts and may do the same for humans.

8 May 2005

Drug combinations improve survival for patients with heart disease

Patients with coronary heart disease who take a combination of three specific drugs have a better chance of survival than those taking single drugs, finds a study in this week's BMJ.

5 May 2005

Cranberries good for the heart

Compounds that occur naturally in cranberries may be good for the heart, researchers at the University of Wisconsin-Madison have found.

5 May 2005

Research suggests potential new strategies for fighting age-related vascular disease

Declining function of cells that help repair the inner lining of blood vessels, known as endothelial progenitor cells, rather than a dwindling supply of the cells, may underlie the increased risk of atherosclerosis and other vascular diseases as people grow older, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Burden of cardiovascular disease will shift to the developing world

In a paper published this week in the premier open-access global health journal PLoS Medicine, Majid Ezzati and colleagues from Harvard School of Public Health conclude that a large proportion of the world's population who live in low-income and middle-income countries should be the focus for intervention against risk factors for cardiovascular disease because major cardiovascular risk factors will increasingly be concentrated in these populations.

3 May 2005