Infectious Diseases News and Research

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UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

Case Western Reserve University has signed an exclusive worldwide licensing agreement granting University Hospitals Case Medical Center rights to a series of diagnostic tests to determine drug resistance and co-receptor tropism in human immunodeficiency virus.

2 Jul 2013

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes. The results, published today in Nature Immunology, suggest a common biochemical thread to multiple diseases and point the way to a new class of therapies that could treat chronic inflammation in these non-infectious diseases without crippling the immune system.

2 Jul 2013

Study shows that PCCs can reverse blood thinning effects of XARELTO in healthy subjects

Janssen Research & Development, LLC announced today results of an open label, single-center, parallel group study showing that a type of medication called prothrombin complex concentrates can reverse the blood thinning effects of XARELTO (rivaroxaban) in healthy subjects.

2 Jul 2013

Increased expression of Scara1 protein might impede progression of Alzheimer's disease: Study

Identification of a protein that appears to play an important role in the immune system's removal of amyloid beta (A-beta) protein from the brain could lead to a new treatment strategy for Alzheimer's disease. The report from researchers at Massachusetts General Hospital (MGH) has been published online in Nature Communications.

2 Jul 2013

LSDF awards $1.5M grants to advance the development of health-related technologies

The Life Sciences Discovery Fund (LSDF) today announced nearly $1.5 million in Proof of Concept grants to Washington for-profit and non-profit organizations to foster translation of health-related technologies from idea to market launch.

2 Jul 2013

Researchers discover role of TonB bacterial protein that causes various diseases

A Kansas State University-led study has discovered the role of a protein in bacteria that cause a wide variety of diseases, including typhoid fever, plague, meningitis and dysentery. The results may lead to new and improved antibiotics for humans and animals.

2 Jul 2013

NanoViricides submits letter of intent to file Orphan Drug Application with EMA for DengueCide

NanoViricides, Inc. announced today that it has submitted its letter of intent to file an Orphan Drug Application with the European Medicines Agency for DengueCide, its drug candidate for the treatment of dengue and dengue hemorrhagic fever.

1 Jul 2013

First clinical study for development of SGX203 to treat pediatric Crohn's disease

Soligenix, Inc. (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat inflammatory diseases and biodefense countermeasures where there remains an unmet medical need, announced today that it has enrolled and treated all patients in the Phase 1 Study BDP-PCD-01; the first clinical study for development of SGX203 (oral beclomethasone 17,21-dipropionate or oral BDP) for the treatment of pediatric Crohn's disease.

1 Jul 2013

Ecology, evolution of infectious diseases to be highlighted at ESA's annual meeting

West Nile virus, Lyme disease and hantavirus. All are infectious diseases spreading in animals and in people. Is human interaction with the environment somehow responsible for the increase in these diseases? The ecology and evolution of infectious diseases will be highlighted at two symposia at the Ecological Society of America's annual meeting, held from Aug. 5-9 in Minneapolis, Minn.

29 Jun 2013

Two symposia focusing on infectious diseases to be held in Minnesota

Two symposia focusing on the ecological dynamics of infectious diseases such as avian influenza, Yellow Fever, and Lyme will take place during the Ecological Society of America's 98th Annual Meeting, held this year in Minneapolis, Minnesota.

29 Jun 2013

Researchers receive NIH grant to study 3-D structure of Plasmodium's genome during parasite's erythrocytic cycle

Malaria is one of the most important infectious diseases in the developing world, with the absence of a vaccine and the development of parasite resistance to commonly used antimalarial drugs complicating efforts to fight the deadly disease.

28 Jun 2013

Janssen receives complete response letter from FDA for XARELTO sNDA

Janssen Research & Development, LLC today announced the U.S. Food and Drug Administration has issued a complete response letter for the supplemental New Drug Application for XARELTO (rivaroxaban) to reduce the risk of stent thrombosis in patients with acute coronary syndrome.

28 Jun 2013

Weekend reading: Chemo revolution, Lyme disease confusion and the residency mismatch

Because I've lived so long with anxiety, there were lots of things I figured I'd never, ever do - having children was one of them. In fact, in my 20s, before I'd managed to stumble on the combination of drugs and exercise that allows me to be as sane as I can expect to be, I was so sure I'd never give birth that I got a tattoo of a giant koi fish extending from one end of my abdomen to the other. ... I found myself in a very ironic situation: my decision to have a child was the result of a sense of stability I enjoyed due to taking an array of anti-anxiety medications that I would be strongly advised by most doctors to stop taking now that I was pregnant (Alissa Nutting, 6/23).

28 Jun 2013

First broad-spectrum drugs to combat human rhinoviruses

Scientists are reporting progress in the search for the first broad-spectrum drugs to combat human rhinoviruses (HRVs), which cause humanity's most common infectious diseases.

27 Jun 2013

Research shows influenza infection increases susceptibility to pneumococcus bacteria by 100-fold

It's been known for more than two centuries that pneumonia cases increase during flu epidemics. But population-level epidemiological studies looking at seasonal patterns of influenza and pneumococcal pneumonia incidence have revealed either a modest association or have failed to identify any signature of interaction between the two.

27 Jun 2013

Second Edition of Human Evolutionary Genetics now available

Garland Science is proud to announce the publication of the long-awaited Second Edition of Human Evolutionary Genetics by Jobling, Hollux, Hurles, Kivisild, and Tyler-Smith.

27 Jun 2013

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Investigators from the Centers for Disease Control and Prevention describe pathologic findings from 40 case reports of fungal infection in patients who had been given contaminated epidural, paraspinal, or intra-articular (into joints) steroid injections and correlate these findings with clinical and laboratory data.

26 Jun 2013

Weill Cornell researchers discover high burden of hypertension in sub-Saharan African country

Based on the experience of a large hospital in Tanzania, Weill Cornell Medical College researchers have discovered a "startlingly" high burden of hypertension in this sub-Saharan African country.

26 Jun 2013

UW receives $10 million to develop paper-based pathogen identification test

The University of Washington has received nearly $10 million from the U.S. Department of Defense to continue a project aimed at building a small, paper-based device that could test for infectious diseases on-demand in areas where diagnostic capabilities are limited.

26 Jun 2013

Study shows risk of Guillain-Barre syndrome after vaccination is extremely low

Patients are not at increased risk of Guillain-Barr- syndrome in the six-week period after vaccination with any vaccine, including influenza, according to a Kaiser Permanente study published in Clinical Infectious Diseases.

25 Jun 2013

Infectious Diseases News and Research

UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Study shows that PCCs can reverse blood thinning effects of XARELTO in healthy subjects

Increased expression of Scara1 protein might impede progression of Alzheimer's disease: Study

LSDF awards $1.5M grants to advance the development of health-related technologies

Researchers discover role of TonB bacterial protein that causes various diseases

NanoViricides submits letter of intent to file Orphan Drug Application with EMA for DengueCide

First clinical study for development of SGX203 to treat pediatric Crohn's disease

Ecology, evolution of infectious diseases to be highlighted at ESA's annual meeting

Two symposia focusing on infectious diseases to be held in Minnesota

Researchers receive NIH grant to study 3-D structure of Plasmodium's genome during parasite's erythrocytic cycle

Janssen receives complete response letter from FDA for XARELTO sNDA

Weekend reading: Chemo revolution, Lyme disease confusion and the residency mismatch

First broad-spectrum drugs to combat human rhinoviruses

Research shows influenza infection increases susceptibility to pneumococcus bacteria by 100-fold

Second Edition of Human Evolutionary Genetics now available

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Weill Cornell researchers discover high burden of hypertension in sub-Saharan African country

UW receives $10 million to develop paper-based pathogen identification test

Study shows risk of Guillain-Barre syndrome after vaccination is extremely low

NGS for Infectious Disease Surveillance eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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