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Alnylam announces clinical data from patisiran Phase 2 OLE study for treatment of patients with FAP

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today initial 12-month clinical data from its ongoing Phase 2 open-label extension (OLE) study with patisiran, an investigational RNAi therapeutic in development for the treatment of transthyretin (TTR)-mediated amyloidosis (ATTR amyloidosis) in patients with familial amyloidotic polyneuropathy (FAP).

24 Apr 2015

New method offers quick spectral analysis of blood and melanin contents in skin sites

Many factors can change skin pigmentation, including aging, exposure to UV light, certain drugs, as well as certain diseases. A simple technique for measuring skin pigmentation could be a helpful tool for research and diagnostics. The same goes for measuring the skin blood content.

24 Apr 2015

Twins pilot study shows genes may make some people more attractive to mosquitoes

The likelihood of being bitten by mosquitoes could be down to our genes, according to a study carried out on twins. Research from the London School of Hygiene & Tropical Medicine found, for the first time, an underlying genetic component to how attractive we are to mosquitoes and this is likely to be caused by genetic control of our body odour.

24 Apr 2015

Case Western Reserve and MIT receive $1.7 million to explore potential treatments for Down syndrome

Thanks to the generosity of a philanthropy dedicated to children's issues, renowned Down syndrome researcher Alberto Costa, MD, PhD, has taken yet another step toward making Northeast Ohio the nation's leader in exploring potential treatments of the genetic condition that affects 400,000 people in the U.S.

23 Apr 2015

Debiopharm announces initiation of Debio 1450 phase II study for treatment of ABSSSI

Debiopharm International SA, part of Debiopharm Group, a Swiss-based global biopharmaceutical company, today announced the start of a clinical phase II study to evaluate Debio 1450 for the treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) due to Staphylococci, including all resistant Staphylococcus strains, tested so far.

23 Apr 2015

Physical forces can affect development of limbs in embryos

University of Toronto engineers and a pediatric surgeon have joined forces to discover that physical forces like pressure and tension affect the development of limbs in embryos--research that could someday be used to help prevent birth defects.

23 Apr 2015

Purdue University study sheds light on how decitabine drug reverses cell damage

A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to treatment.

23 Apr 2015

VisualDx tool aids physicians in diagnosing dermatologic conditions

In the first major study to examine the use of a computer-assisted, photo-driven differential diagnosis generator for skin conditions, researchers at the Perelman School of Medicine at the University of Pennsylvania found physicians routinely used the tool, without an increase in calling for inpatient dermatology consultations.

23 Apr 2015

Advances in thoracic surgery: an interview with Dan Wildman, VP Global Franchise Strategy & Innovation- Ethicon

Without a doubt, one of the most significant developments in thoracic surgery was the advent of video-assisted thoracoscopic surgery or VATS in the 1990s...

22 Apr 2015

Scientists identify protein that could help tame severe inflammation

Researchers have identified a protein that offers a new focus for developing targeted therapies to tame the severe inflammation associated with multiple sclerosis (MS), colitis and other autoimmune disorders.

22 Apr 2015

French clinicians diagnose first case of rabies since 2003

A team of French clinicians has diagnosed the first case of rabies in that country since 2003. Only 20 cases of human rabies had been diagnosed in France between 1970 and 2003. Moreover, the patient was unaware of having been bitten.

22 Apr 2015

James Shapiro's latest research could soon mark new standard for diabetes treatment

James Shapiro, one of the world's leading experts in emerging treatments of diabetes, can't help but be excited about his latest research. The results he says, could soon mark a new standard for treatment--not only in diabetes, but in several other diseases as well.

22 Apr 2015

Two existing drugs may reverse damage caused by multiple sclerosis

A pair of topical medicines already alleviating skin conditions each may prove to have another, even more compelling use: instructing stem cells in the brain to reverse damage caused by multiple sclerosis.

21 Apr 2015

MSU researchers receive $7 million NIH grant to study link between belly fat and high blood pressure

Michigan State University researchers, who were the first to suggest that high blood pressure could be caused by belly fat hormones "talking" with blood vessels in the abdomen, have received a nearly $7 million National Institutes of Health grant to further their work.

21 Apr 2015

Two new research papers reveal how breast cancer cells avoid anoikis

Two new papers from the lab of Zach Schafer, Coleman Assistant Professor of Cancer Biology at the University of Notre Dame, offer insights into how breast cancer cells avoid anoikis, which is cell death induced by detachment from the extracellular matrix (ECM).

21 Apr 2015

May issue of Red Journal focuses on role of radiation therapy in current lymphoma treatment

The "Radiation and the Modern Management of Lymphoma" issue (May 1, 2015) of the International Journal of Radiation Oncology • Biology • Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology, is focused on the integral role of radiation therapy in current lymphoma treatment.

17 Apr 2015

Yale University launches clinical study to evaluate personalized medicine for metastatic melanoma

Yale University has launched a multicenter clinical trial, sponsored by Stand Up to Cancer and Melanoma Research Alliance, that will apply the latest in personalized medicine technology to treat metastatic melanoma. The trial, for which Yale is a lead site, will enroll patients lacking a particular genetic mutation for whom immune therapy did not work or was not an option.

16 Apr 2015

Research: Stem cell injection may soon slow or reverse effects of age-related macular degeneration

An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there is no treatment that slows the progression of the disease, which is the leading cause of vision loss in people over 65.

16 Apr 2015

Researchers examine how probiotics can help improve health, prevent disease

In recent years, research into the benefits of gut bacteria has exploded. Scientists across the globe are examining how these microbes can help improve health and prevent disease.

16 Apr 2015

Itraconazole drug shows potential in cancer treatment

A common anti-fungal treatment has joined the ranks of drugs that may be suitable for use in treating cancer, according to research from the Repurposing Drugs in Oncology (ReDO) project published in ecancermedicalscience.

16 Apr 2015

Skin News and Research

Alnylam announces clinical data from patisiran Phase 2 OLE study for treatment of patients with FAP

New method offers quick spectral analysis of blood and melanin contents in skin sites

Twins pilot study shows genes may make some people more attractive to mosquitoes

Case Western Reserve and MIT receive $1.7 million to explore potential treatments for Down syndrome

Debiopharm announces initiation of Debio 1450 phase II study for treatment of ABSSSI

Physical forces can affect development of limbs in embryos

Purdue University study sheds light on how decitabine drug reverses cell damage

VisualDx tool aids physicians in diagnosing dermatologic conditions

Advances in thoracic surgery: an interview with Dan Wildman, VP Global Franchise Strategy & Innovation- Ethicon

Scientists identify protein that could help tame severe inflammation

French clinicians diagnose first case of rabies since 2003

James Shapiro's latest research could soon mark new standard for diabetes treatment

Two existing drugs may reverse damage caused by multiple sclerosis

MSU researchers receive $7 million NIH grant to study link between belly fat and high blood pressure

Two new research papers reveal how breast cancer cells avoid anoikis

May issue of Red Journal focuses on role of radiation therapy in current lymphoma treatment

Yale University launches clinical study to evaluate personalized medicine for metastatic melanoma

Research: Stem cell injection may soon slow or reverse effects of age-related macular degeneration

Researchers examine how probiotics can help improve health, prevent disease

Itraconazole drug shows potential in cancer treatment

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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