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Scientists discover novel species of betapolyomavirus in Kenya

A new study published as a pre-proof in the journal Virologica Sinica, is follow-up research to a previous study on the discovery of novel rodent viruses of various RNA viral families in Kenya.

12 Jun 2022

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

New statement on best practice recommendations for the care of women experiencing menopause

Best practice recommendations for healthcare professionals providing help and support to women experiencing menopause have been issued in a joint position statement from the British Menopause Society, Royal College of Obstetricians and Gynaecologists and the Society for Endocrinology.

10 Jun 2022

Androgens contribute to sex bias in bladder cancer

Male sex hormones interfere with the body's ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study co-led by a Cedars-Sinai Cancer investigator.

10 Jun 2022

Creating CAR T cells without an immune brake

T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells.

10 Jun 2022

Transgender college students more likely to suffer from sleep disorders and mental health issues

Transgender individuals are more likely to experience discrimination, isolation, and lack of social support.

10 Jun 2022

Study investigates SARS-CoV-2 escape from nirmatrelvir

Researchers assessed SARS-CoV-2 Alpha, Delta, and Omicron variants’ resistance to nirmatrelvir, a protease inhibitor of SARS-CoV-2.

10 Jun 2022

The physiological relevance and effects of probable in vivo transformation of CBD to delta9-THC in humans

Researchers reviewed studies on the probable conversion of orally administered cannabidiol (CBD) to delta9-tetrahydrocannabinol (delta9-THC or THC) in humans.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

A study of the lead agent (CPI-613) in a class of anticancer drugs undergoing Food and Drug Administration (FDA) approved clinical trials reveals that CPI-613 is effective against most carcinoma cell lines, and, used in combination, could have efficacy against reducing some tumors.

9 Jun 2022

A comparison of SARS-CoV-2 and influenza cytokine storms

In a recent study published in the Journal of Interferon & Cytokine Research, researchers compared the cytokine storms of pandemic influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

9 Jun 2022

Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

A protein that the body naturally produces could become an important new immunotherapy drug in the cache of cancer-fighting tools available to oncologists.

9 Jun 2022

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Each year, dentists in the United States perform more than 15 million root canals on infected teeth, removing the inflamed pulp and filling the emptied canal with inert materials such as rubber and cement. What remains is a mineral shell in place of a living tooth.

9 Jun 2022

Genomic analysis provides a deeper understanding of DCIS biology

A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion.

9 Jun 2022

Targeting fatty acid metabolism holds promise for Parkinson's disease

The human brain is lipid rich. Lipids and fatty acids contribute to many important cellular processes. Alpha-synuclein - a protein that plays a critical role in Parkinson's disease (PD) - is known to interact with and alter the balance of lipids and fatty acids.

9 Jun 2022

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

9 Jun 2022

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Why doesn't every cancer patient respond to immunotherapy? That's the question that researcher Daniel Peeper is looking to answer.

9 Jun 2022

Three risk factors can help identify elderly patients in need for frequent emergency house calls

In Japan's rapidly aging society, elderly people commonly receive medical treatment at home from doctors who make house calls instead of in a hospital setting.

9 Jun 2022

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

From Curia 9 Jun 2022

Largest-ever series of case studies shows phage therapy’s success in more than half of the patients

The number of reported cases using viruses to treat deadly Mycobacterium infections just went up by a factor of five. In a new study, a team led by researchers from the University of Pittsburgh and the University of California San Diego report 20 new case studies on the use of the experimental treatment, showing the therapy's success in more than half of the patients.

9 Jun 2022

Therapy News and Research

Scientists discover novel species of betapolyomavirus in Kenya

New machine learning algorithm finds a gene signature characteristic of tumors

New statement on best practice recommendations for the care of women experiencing menopause

Androgens contribute to sex bias in bladder cancer

Creating CAR T cells without an immune brake

Transgender college students more likely to suffer from sleep disorders and mental health issues

Study investigates SARS-CoV-2 escape from nirmatrelvir

The physiological relevance and effects of probable in vivo transformation of CBD to delta9-THC in humans

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

A comparison of SARS-CoV-2 and influenza cytokine storms

Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Genomic analysis provides a deeper understanding of DCIS biology

Targeting fatty acid metabolism holds promise for Parkinson's disease

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Three risk factors can help identify elderly patients in need for frequent emergency house calls

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

Largest-ever series of case studies shows phage therapy’s success in more than half of the patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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