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Antihypertensive drugs may protect against COVID-19 in heart patients

Common drugs used in high blood pressure, heart failure, and diabetic patients with kidney damage, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), could be protective in patients with COVID-19.

31 Mar 2020

Spit and feces test positive for SARS CoV-2 even after recovery

A new study reveals that samples of sputum and feces continue to test positive for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus even after a person has recovered from COVID-19 and nasopharyngeal secretions test negative for the virus.

31 Mar 2020

FDA to trial malaria drugs Chloroquine and Hydroxychloroquine for COVID-19

The U.S. Food and Drug Administration (FDA) this week provided the necessary authorization for clinical trials of chloroquine and hydroxychloroquine for the treatment of the novel coronavirus. These two drugs have been claimed by President Donald Trump to be a potential treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which causes COVID-19 disease. To date, there has been no conclusive proof regarding the safety and efficacy of these drugs in COVID-19 cases, say officials.

31 Mar 2020

COVID-19: Ban on eating wild meat deprives some forest communities

As efforts to curb the COVID-19 pandemic accelerate around the world, wildlife conservationists have welcomed a move by the Chinese government to outlaw the hunting and consumption of all terrestrial wild animals.

31 Mar 2020

Novel, affordable pneumonia vaccine tested in human patients

A novel vaccine against pneumonia that is less expensive and more effective than those currently used in Brazil is being tested in human patients.

31 Mar 2020

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Scientists have developed a new immunotherapy that eradicates solid tumors in mice without adverse side effects, according to a new study published today in eLife.

31 Mar 2020

Potential new method of breast cancer treatment using androgen receptor

Scientists may have discovered a new therapeutic approach to treat ER+ breast cancer using androgen receptor-stimulating drugs.

31 Mar 2020

Horizon Discovery and Pharmahungary report positive early-stage results for novel micro-RNA therapeutic for ischemic heart diseases

Horizon Discovery Group plc and Pharmahungary Group announced positive early-stage results for a novel micro-RNA therapeutic for ischemic heart diseases.

31 Mar 2020

Why do men stop treatment for erectile dysfunction?

A new study published in the journal IJIR: Your Sexual Medicine Journal in March 2020 reports the most common reasons why men stop their treatment for erectile dysfunction. The most common reasons were that the treatment did not work, cost too much, or had unacceptable side effects. Loss of interest in sexual relationships was another primary reason.

31 Mar 2020

Researchers develop chemically modified phage capsid that “stifles” influenza viruses

A new approach brings the hope of new therapeutic options for suppressing seasonal influenza and avian flu: On the basis of an empty - and therefore non-infectious - shell of a phage virus, researchers from Berlin have developed a chemically modified phage capsid that "stifles" influenza viruses.

31 Mar 2020

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk of clinically relevant bleeding over 12 months compared to aspirin plus Brilinta in high-risk coronary patients.

From AstraZeneca 30 Mar 2020

Direct oral anticoagulant more effective in lowering risk of VTE after common orthopedic surgeries

The direct oral anticoagulant rivaroxaban dramatically cut the likelihood of serious venous thromboembolism (VTE) in people recovering from lower limb orthopedic surgery requiring immobilization in comparison with enoxaparin, another anticoagulant agent, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

10-year follow-up study shows safety, efficacy of stenting compared with bypass surgery

In a study with the longest follow-up to date of patients with a high-risk form of heart disease known as left main coronary artery disease (LMCAD), researchers found no significant differences in rates of death, heart attack or stroke between patients who were treated with a stent and those who underwent heart bypass surgery.

30 Mar 2020

Low-dose rivaroxaban reduces adverse heart events in symptomatic PAD post-intervention

People with symptomatic peripheral artery disease who took the blood thinner rivaroxaban with aspirin after undergoing a procedure to treat blocked arteries in the leg (lower extremity revascularization) had a 15% reduction in the risk of major adverse limb and cardiovascular events when compared with those receiving aspirin alone, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Researchers develop a 'cardiac patch with bioink' to repair the heart

The heart is the driving force of circulating blood in the body and pumps blood to the entire body by repeating contraction and relaxation of the heart muscles continuously.

30 Mar 2020

TAVR shows high rate of success and low risk of death in patients with bicuspid valve

Transcatheter aortic valve replacement procedures had a high rate of success and low risk of death or disabling stroke at 30 days in patients with a bicuspid, or two-leaflet, aortic valve, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Renal denervation effective in patients with untreated high blood pressure

Three months after undergoing renal denervation —a procedure that delivers energy to overactive nerves leading to the kidney to decrease their activity—patients with untreated high blood pressure had statistically significant reductions in average blood pressure over 24 hours compared with patients who underwent a sham procedure and experienced no major adverse effects, according to results from the SPYRAL-HTN OFF MED pivotal trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

New method to treat blindness using retinal cell production

Scientists in Sweden have innovated a method of treating blindness using embryonic stem cells to produce retinal cells.

30 Mar 2020

How long to a coronavirus vaccine?

The whole world is waiting for one. A vaccine is the only thing that could conceivably save the world from a horrifying cascade of deaths, other than a miracle, it seems.

29 Mar 2020

Efficacy News and Research

Antihypertensive drugs may protect against COVID-19 in heart patients

Spit and feces test positive for SARS CoV-2 even after recovery

FDA to trial malaria drugs Chloroquine and Hydroxychloroquine for COVID-19

COVID-19: Ban on eating wild meat deprives some forest communities

Novel, affordable pneumonia vaccine tested in human patients

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Potential new method of breast cancer treatment using androgen receptor

Horizon Discovery and Pharmahungary report positive early-stage results for novel micro-RNA therapeutic for ischemic heart diseases

Why do men stop treatment for erectile dysfunction?

Researchers develop chemically modified phage capsid that “stifles” influenza viruses

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Direct oral anticoagulant more effective in lowering risk of VTE after common orthopedic surgeries

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

10-year follow-up study shows safety, efficacy of stenting compared with bypass surgery

Low-dose rivaroxaban reduces adverse heart events in symptomatic PAD post-intervention

Researchers develop a 'cardiac patch with bioink' to repair the heart

TAVR shows high rate of success and low risk of death in patients with bicuspid valve

Renal denervation effective in patients with untreated high blood pressure

New method to treat blindness using retinal cell production

How long to a coronavirus vaccine?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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