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Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

In a recent study posted to the medRxiv* preprint server, investigators in Singapore showed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection elicited broadly specific virus-selective nasal resident CD8 and CD4 T cells.

24 May 2022

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

In a recent study published in the journal Cell, researchers demonstrated that antibodies generated due to breakthrough infection (BTI) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron in vaccinated individuals could neutralize all VOCs.

24 May 2022

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Bone tissue homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts.

23 May 2022

Study sheds light on the molecular biology behind genetic epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has not just affected the functioning of the protein in question – it could also curb the functioning of several closely related proteins.

23 May 2022

Antibiotic rifampicin attenuates C9orf72-linked dementia in genetically modified mice

What did Stephen Hawking and Mao Zedong have in common? They both suffered from Amyotrophic Lateral Sclerosis (ALS), a cure for which remains elusive. Scientists from Osaka Metropolitan University took an important step toward prevention of ALS and another brain disorder called Frontotemporal dementia (FTD) with their research on the effects of the antibiotic rifampicin on genetically modified mice.

23 May 2022

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Researchers utilize the ATLAS screening assay to reveal the antigen response profiles of T-cells to different SARS-CoV-2 variants.

23 May 2022

Synthetic biologists interrogate single-celled survivalists to understand stress response

Rice University synthetic biologists and bioengineers are preparing to interrogate some single-celled survivalists to find out how they deal with stress.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Gabapentin treatment may enhance recovery of movement after a stroke

The drug gabapentin, currently prescribed to control seizures and reduce nerve pain, may enhance recovery of movement after a stroke by helping neurons on the undamaged side of the brain take up the signaling work of lost cells, new research in mice suggests.

23 May 2022

Low GI diet could help heart disease patients control their body weight and waistline

Eating low glycemic index foods promotes a healthier body shape in patients with coronary artery disease, according to a study presented at ACNAP-EuroHeartCare Congress 2022, a scientific congress of the European Society of Cardiology.

23 May 2022

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Researchers observed SARS-CoV-2 downregulates the expression of MHC class I molecules.

23 May 2022

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Researchers designed an efficient vaccine design against SARS-CoV-2 infections.

23 May 2022

Study shows a strong negative association between BNT162b2 vaccination-induced S1 IgG concentration and age

Researchers assessed the impact of BNT162b2 coronavirus disease 2019 (COVID-19) vaccination on antibody acquisition.

23 May 2022

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

A new paper presents the results of a mouse study using the repurposed antibacterial drug clofoctol against this virus.

23 May 2022

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Resarchers discuss the ability of shark-derived antibodies to protect against multiple variants of SARS-CoV-2.

23 May 2022

SARS-CoV-2 Omicron subvariants are increasingly escaping immunity

In a recent study posted to the medRxiv* preprint server, researchers evaluated the neutralization evasion of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages.

22 May 2022

Deep visual proteomics is redefining cancer diagnostics

In a recent study published in the journal Nature Biotechnology, researchers introduced deep visual proteomics (DVP), an amalgamation of artificial intelligence (AI) for image analysis and mass spectrometry (MS) for proteomic profiling of biological samples.

22 May 2022

Protein C News and Research

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Study sheds light on the molecular biology behind genetic epilepsy

Antibiotic rifampicin attenuates C9orf72-linked dementia in genetically modified mice

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Synthetic biologists interrogate single-celled survivalists to understand stress response

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Gabapentin treatment may enhance recovery of movement after a stroke

Low GI diet could help heart disease patients control their body weight and waistline

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Study shows a strong negative association between BNT162b2 vaccination-induced S1 IgG concentration and age

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

SARS-CoV-2 Omicron subvariants are increasingly escaping immunity

Deep visual proteomics is redefining cancer diagnostics

Reduced exercise capacity is common in long COVID patients

Anti-SARS-CoV-2 titers predict COVID severity

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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