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New findings may lead to first new animal model for hepatitis C virus

By differentiating monkey stem cells into liver cells and inducing successful infection, researchers from the Icahn School of Medicine at Mount Sinai have shown for the first time that the hepatitis C virus can replicate in monkeys, according to research published in the journal Gastroenterology.

3 Aug 2013

Research: Larger lungs are associated with increased chance of survival

Transplant teams have long tried to match the size of donor lungs to the size of the recipient as closely as possible, concerned that lungs of the wrong size could lead to poor lung function and poor outcomes.

2 Aug 2013

New finding suggests potential to improve safety, performance of reprogrammed cells

The enormous promise of regenerative medicine is matched by equally enormous challenges. But a new finding by a team of researchers led by Weill Cornell Medical College has the potential to improve both the safety and performance of reprogrammed cells.

2 Aug 2013

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers

2 Aug 2013

Research opens potential new avenue for cancer treatment

Scientists at The University of Texas MD Anderson who identified a protein's dual role in cancer promotion have discovered a way to shut it down, opening a potential new avenue for cancer treatment.

2 Aug 2013

Study: Ultrasound treatments may prevent acute kidney injury

Ultrasound treatments may prevent acute kidney injury that commonly arises after major surgery, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that this simple and noninvasive therapy may be an effective precaution for patients at risk.

2 Aug 2013

Study suggests silicon nanocrystals may be safe tool for diagnostic imaging in humans

Tiny silicon crystals caused no health problems in monkeys three months after large doses were injected, marking a step forward in the quest to bring such materials into clinics as biomedical imaging agents, according to a new study.

1 Aug 2013

Researchers identify novel approach to enhance tissue repair and organ regeneration

Because most human tissues do not regenerate spontaneously, advances in tissue repair and organ regeneration could benefit many patients with a wide variety of medical conditions.

1 Aug 2013

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

Pain is defined by the sufferer’s experience. Pain may be severe because it is intense, frequent or sustained, and because it is distressing. The severity of pain is not simply due to what is going on in the joint, but is also affected by how the body processes the pain signals, and the context in which it is experienced.

31 Jul 2013

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

With oral anticoagulant rivaroxaban set to be subsidised under the Pharmaceutical Benefits Scheme (PBS) for preventing stroke, NPS MedicineWise is urging people to talk to their doctor before stopping or making any changes to their anticoagulant medicines.

30 Jul 2013

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Genotype 1 is, worldwide, the most prevalent genotype of the hepatitis C virus. It accounts for around seventy percent of all hepatitis C infections.

30 Jul 2013

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

The USPSTF agreed with the CDC that since most patients (75%) who are currently infected with hepatitis C were born between 1945 - 1965, and since risk-based screening has not been successful in identifying these individuals, that a one time age-based hepatitis C blood test was necessary.

29 Jul 2013

Hepatocytes from stem-cell derived human liver cells increase survival of animals with liver disease

Researchers have generated functional hepatocytes from human stem cells, transplanted them into mice with acute liver injury, and shown the ability of these stem-cell derived human liver cells to function normally and increase survival of the treated animals.

29 Jul 2013

Miriam researcher calls for new strategies to better manage, improve treatment for HCV infection

A Miriam Hospital researcher has joined forces with international colleagues to call for new strategies to better manage and improve assessment and treatment for hepatitis C (HCV) infection in individuals who inject drugs.

26 Jul 2013

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

PerFluoroAlkyl Substances (PFASs) and precursor compounds have been used in a wide variety of commercial and industrial products over the past six decades. Applications include water and oil repellent coatings, e.g. for textiles, paper products, carpets and food packaging, pharmaceuticals and surfactants in cleaning products and fire-fighting foams.

25 Jul 2013

Combination treatment can reduce hepatitis C infection in people who inject drugs

The burden of liver disease could be dramatically reduced by scaling up the combination of interventions for hepatitis C infection among people who inject drugs according to University of Bristol researchers. The findings, published today [24 July], form part of new global recommendations on treating the virus.

25 Jul 2013

WHO urges governments to act against five hepatitis viruses that cause severe liver infections

On World Hepatitis Day (28 July), the World Health Organization (WHO) is urging governments to act against the five hepatitis viruses that can cause severe liver infections and lead to 1.4 million deaths every year. Some of these hepatitis viruses, most notably types B and C, can also lead to chronic and debilitating illnesses such as liver cancer and cirrhosis, in addition to loss of income and high medical expenses for hundreds of millions of people worldwide.

24 Jul 2013

Report shows that fatal rabies virus is transmitted through transplanted kidney

An investigation into the source of a fatal case of raccoon rabies virus exposure indicates the individual received the virus via a kidney transplant 18 months earlier, findings suggesting that rabies transmitted by this route may have a long incubation period, and that although solid organ transplant transmission of infectious encephalitis is rare, further education to increase awareness is needed, according to a study in the July 24/31 issue of JAMA.

24 Jul 2013

Study reveals fungus coating on stored food may worsen AIDS epidemic

A type of fungus coating much of the stored corn, wheat, rice and nuts in developing countries may be quietly worsening the AIDS epidemic, according to a paper published today in the World Mycotoxin Journal.

24 Jul 2013

Researchers provide new model for studying drug targets and therapies for AIH

A gene mutation disrupts the activity of certain immune cells and causes the immune system to erroneously attack the liver, according to a new animal study from the Icahn School of Medicine at Mount Sinai.

24 Jul 2013

Liver News and Research

New findings may lead to first new animal model for hepatitis C virus

Research: Larger lungs are associated with increased chance of survival

New finding suggests potential to improve safety, performance of reprogrammed cells

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Research opens potential new avenue for cancer treatment

Study: Ultrasound treatments may prevent acute kidney injury

Study suggests silicon nanocrystals may be safe tool for diagnostic imaging in humans

Researchers identify novel approach to enhance tissue repair and organ regeneration

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

Hepatocytes from stem-cell derived human liver cells increase survival of animals with liver disease

Miriam researcher calls for new strategies to better manage, improve treatment for HCV infection

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

Combination treatment can reduce hepatitis C infection in people who inject drugs

WHO urges governments to act against five hepatitis viruses that cause severe liver infections

Report shows that fatal rabies virus is transmitted through transplanted kidney

Study reveals fungus coating on stored food may worsen AIDS epidemic

Researchers provide new model for studying drug targets and therapies for AIH

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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