Protein C News and Research

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Can human coronaviruses infect the GI tract?

Researchers review current findings on how human coronaviruses like SARS-CoV-2 might cause GI symptoms.

22 May 2022

Scientists discover how immune proteins defend plants against invading microorganisms

Scientists from the Max Planck Institute for Plant Breeding Research and the University of Cologne, Germany, have discovered a novel biochemical mechanism explaining how immune proteins defend plants against invading microorganisms.

20 May 2022

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

Army scientists determined that the body's own natural immune response contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.

20 May 2022

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Preventing atherosclerosis, the underlying cause of heart disease, means scientists need to understand how immune cells drive inflammation in the arteries.

20 May 2022

Discoveries may lead to new ways to treat patients with Allan-Herndon-Dudley syndrome

Two recent discoveries co-led by scientists at Cedars-Sinai may help lead to new ways to treat patients with Allan-Herndon-Dudley syndrome (AHDS), a brain development disorder that causes severe intellectual disability and problems with movement.

20 May 2022

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Scientists at St. Jude Children's Research Hospital have solved an immunology puzzle. A CD8+ T cell can have two functionally distinct daughter cells after it divides, despite the cells being genetically identical.

20 May 2022

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.

20 May 2022

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Researchers explored whether surface ACE2 carried by EVs can facilitate the entry of SARS-CoV-2 into host cells.

20 May 2022

Important methodology for targeting conserved epitopes of SARS-CoV-2 and an immune-focused approach in pan-sarbeco and universal CoV vaccine design

A new study has focused on designing immunogens associated with the conserved region of the spike protein of SARS-CoV-2.

20 May 2022

The link between androgens and COVID-19

A new paper examines the association between androgens and COVID-19, as revealed by the research carried out on this topic throughout the pandemic.

20 May 2022

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Investigators demonstrated S100A9 as an inflammatory biomarker among hospitalized SARS-CoV-2 patients.

20 May 2022

Serologic response to SARS-CoV-2 may predict COVID-19 severity

A new study reported that antibody titers against SARS-CoV-2 could serve as a marker for the severity of COVID-19.

20 May 2022

Natural immunity weak and short-lived in unvaccinated after Omicron infection

In a recent study posted to the journal Nature, researchers showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection without SARS-CoV-2 vaccination conferred poor cross-variant neutralizing capacities.

20 May 2022

Comparison of COVID-induced ARDS and sepsis-induced ARDS

In a recent study posted to the medRxiv* preprint server, researchers compared the pathophysiology of coronavirus disease 2019 (COVID-19) and bacterial sepsis-induced acute respiratory distress syndrome (ARDS).

20 May 2022

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

How does the immune system remember and recognize viral invaders it has encountered in the past? A trio of newly published studies of people infected with SARS-CoV-2, vaccinated against the virus or both, are providing tantalizing new clues about the factors that influence the speed and magnitude of the immune system's response to subsequent infection with variants of SARS-CoV-2.

19 May 2022

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.

19 May 2022

L452R mutation a key player in the evolution of SARS-CoV-2

In a recent study published in the bioRxiv* preprint server, researchers analyzed the characteristics of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron subvariants BA.4, BA.5, and BA.2.12.1.

19 May 2022

Epistatic drift leads to unpredictability in protein evolution

A critical goal in genetics and evolution is predicting the effects of mutations that may happen in the future and inferring the effects of those that happened in the past.

19 May 2022

Researchers discover possible connection between harmful amyloid production and COVID-19 symptoms

In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers at Linköping University, Sweden, have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid.

19 May 2022

Genetic variants may help explain the variability in COVID-19 severity, study suggests

Though underlying medical conditions play an important role, many aspects of why COVID-19 severity can differ vastly from one to another has remained unclear.

19 May 2022

Protein C News and Research

Can human coronaviruses infect the GI tract?

Scientists discover how immune proteins defend plants against invading microorganisms

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Discoveries may lead to new ways to treat patients with Allan-Herndon-Dudley syndrome

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Important methodology for targeting conserved epitopes of SARS-CoV-2 and an immune-focused approach in pan-sarbeco and universal CoV vaccine design

The link between androgens and COVID-19

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Serologic response to SARS-CoV-2 may predict COVID-19 severity

Natural immunity weak and short-lived in unvaccinated after Omicron infection

Comparison of COVID-induced ARDS and sepsis-induced ARDS

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

Plastins may promote disease when they act like workaholics and disrupt cellular environment

L452R mutation a key player in the evolution of SARS-CoV-2

Epistatic drift leads to unpredictability in protein evolution

Researchers discover possible connection between harmful amyloid production and COVID-19 symptoms

Genetic variants may help explain the variability in COVID-19 severity, study suggests

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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