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Researchers highlight distinct subtypes of myalgic encephalomyelitis

Researchers have identified distinct subtypes of myalgic encephalomyelitis (ME/CFS - also referred to as chronic fatigue syndrome) and there is renewed hope that treatments are available for this debilitating neurological illness.

7 May 2008

Blocked brain enzyme shows potential as target for appetite control, weight loss and blood sugar management

Imagine being able to tone down appetite and promote weight loss, while improving the body's ability to handle blood sugar levels.

6 May 2008

New discovery on role of vital protein that fights meningitus

A University of Leicester researcher has discovered how a protein in the blood - linked to defence against meningitis - plays a more vital role than previously understood in the body's immune defence system.

6 May 2008

Geron Corporation awarded UK grant funding for human embryonic stem cell research

Geron Corporation announced today two grant awards to the University of Edinburgh from the UK Stem Cell Foundation, with funding from the Medical Research Council and Scottish Enterprise.

6 May 2008

It's official - there's a rogue fat gene!

Scientists from Oxford and Cambridge say in their second discovery they have found new genetic variants that influence fat mass, weight and risk of obesity and increase the chances of being fat, which may explain why some people are always battling with their weight.

5 May 2008

New funding to deliver targeted research

The Medical Research Council is launching a new funding stream to encourage the development of new therapies, interventions and diagnostic tools, and also of research tools used in their development by adopting problem-led approaches.

2 May 2008

Antidepressant amitriptyline shown to alleviate symptoms of irritable bowel syndrome

Researchers at Mattel Children's Hospital UCLA have found that low-dose antidepressant therapy can significantly improve the overall quality of life for adolescents suffering from irritable bowel syndrome (IBS).

1 May 2008

Small molecule nutlin-3a activates an important cancer suppressor gene

By activating a cancer suppressor gene, a small molecule called nutlin-3a can block cancer cell division, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

1 May 2008

Cocaine addicts who use other substances have more mental health problems

A study carried out by Spanish scientists shows that cocaine users who take other addictive substances demonstrate a higher risk of mental health problems.

1 May 2008

First sequence-based map of large-scale structural variation across the human genome

A nationwide team of researchers, funded in part by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has produced the first sequence-based map of large-scale structural variation across the human genome. The work, published today in the journal Nature, provides a starting point to examine how such DNA variation contributes to human health and disease.

30 Apr 2008

Discovery of quick method for making human monoclonal antibodies against flu

Human monoclonal antibodies (mAbs) - highly specific, identical, infection-fighting proteins produced in large quantities in the lab in cell lines that are derived from a single antibody-producing cell - against influenza can be rapidly produced in the lab, according to a new report from scientists supported by the National Institutes of Health (NIH).

30 Apr 2008

Scientists determine drug target for the most potent botulinum neurotoxin

Botulinum neurotoxin - responsible for the deadly food poisoning disease botulism and for the beneficial effects of smoothing out facial wrinkles - can also be used as a dreaded biological weapon. When ingested or inhaled, less than a billionth of an ounce can cause muscle paralysis and eventual death. Although experimental vaccines administered prior to exposure can inhibit the destructive action of this neurotoxin - the most deadly protein known to humans - no effective pharmacological treatment exists.

29 Apr 2008

Human protein may offer novel target for blocking HIV infection

A research group supported by the National Institutes of Health (NIH) has uncovered a new route for attacking the human immunodeficiency virus (HIV) that may offer a way to circumvent problems with drug resistance. In findings published today in the online edition of the Proceedings of the National Academy of Sciences, the researchers report that they have blocked HIV infection in the test tube by inactivating a human protein expressed in key immune cells.

29 Apr 2008

New research suggests hypertonic, hyperviscous fluids may be better treatment for severe blood loss

Intravenous administration of isotonic fluids is the standard emergency treatment in the U.S. for patients with severe blood loss, but UC San Diego bioengineering researchers have reported improved resuscitation with a radically different approach. Building on earlier studies in humans that have shown benefits of intravenous fluids that are eight times saltier than normal saline, the researchers combined hypertonic saline with viscosity enhancers that thicken blood.

29 Apr 2008

Abmormal behaviour of osteoglycin gene linked to heart and kidney problems

A gene that can cause the heart to become enlarged, greatly increasing the risk of heart attacks and heart failure, is identified today in a new study.

28 Apr 2008

Scientists discover way to increase metabolism for weight loss

Scientists from Melbourne's Howard Florey Institute have discovered a way to aid weight loss and reduce the likelihood of developing diabetes by manipulating fat cells to increase the body's metabolism.

28 Apr 2008

U.S., British HIV/AIDS researchers pessimistic about prospects of vaccine, survey finds

Leading HIV/AIDS researchers in Britain and the U.S. are pessimistic about the prospects of developing an HIV vaccine following the recent failure of a Merck vaccine candidate, according to a survey conducted by London's Independent, the Independent reports (Connor/Green, Independent, 4/24).

26 Apr 2008

Doctors should consider alternatives to antibiotics for sinusitis

When suffering through a sinus infection, many people ask for an antibiotic to speed their recovery. However, a recent review of clinical trials found that while antibiotics can provide minor improvements in uncomplicated sinusitis cases, most patients recover without the drugs within two weeks.

24 Apr 2008

Interventions for enhancing medication adherence

Patients often do not take the medicines their doctors prescribe, and a new review of existing research suggests that there is no proven way to get them to follow directions for long periods.

24 Apr 2008

Functional magnetic resonance imaging reveals brain circuitry associated with social status

Human imaging studies have for the first time identified brain circuitry associated with social status, according to researchers at the National Institute of Mental Health (NIMH) of the National Institutes of Health.

23 Apr 2008

Medical Research News and Research

Researchers highlight distinct subtypes of myalgic encephalomyelitis

Blocked brain enzyme shows potential as target for appetite control, weight loss and blood sugar management

New discovery on role of vital protein that fights meningitus

Geron Corporation awarded UK grant funding for human embryonic stem cell research

It's official - there's a rogue fat gene!

New funding to deliver targeted research

Antidepressant amitriptyline shown to alleviate symptoms of irritable bowel syndrome

Small molecule nutlin-3a activates an important cancer suppressor gene

Cocaine addicts who use other substances have more mental health problems

First sequence-based map of large-scale structural variation across the human genome

Discovery of quick method for making human monoclonal antibodies against flu

Scientists determine drug target for the most potent botulinum neurotoxin

Human protein may offer novel target for blocking HIV infection

New research suggests hypertonic, hyperviscous fluids may be better treatment for severe blood loss

Abmormal behaviour of osteoglycin gene linked to heart and kidney problems

Scientists discover way to increase metabolism for weight loss

U.S., British HIV/AIDS researchers pessimistic about prospects of vaccine, survey finds

Doctors should consider alternatives to antibiotics for sinusitis

Interventions for enhancing medication adherence

Functional magnetic resonance imaging reveals brain circuitry associated with social status

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