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Combined treatment approach proves to be beneficial for prostate cancer patients

Practice-changing research from Cedars-Sinai Cancer shows that a combination of androgen deprivation therapy - a commonly used hormone injection - plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients' prostate cancer at bay for five years.

26 May 2022

Children from historically marginalized groups or poor backgrounds less likely to survive neuroblastoma

Children with high-risk neuroblastoma had worse outcomes if they were from certain racial/ethnic groups or were on public rather than private insurance, despite being treated in clinical trials with standardized protocols, according to a study led by investigators from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

26 May 2022

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

26 May 2022

Aston University’s new antibiotic combination forms part of a lifesaving treatment for cystic fibrosis

A new antibiotic combination developed by researchers at Aston University has formed part of a lifesaving treatment used in the USA.

26 May 2022

Multidisciplinary care improves outcomes from chronic kidney disease

It is generally agreed that a team of individuals with unique talents and skills offers the potential to achieve more than any person can achieve alone.

26 May 2022

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022

Common type 2 diabetes medication could be the key to improving fertility in women with obesity

Researchers may have found a solution to improving fertility in women with obesity, following a successful trial in mice using diabetes medication to reduce blood glucose levels.

26 May 2022

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.

25 May 2022

NYU Abu Dhabi research could pave the way for more effective cancer treatments

A team led by Professor of Biology, Senior Vice Provost of Research at NYU Abu Dhabi, and UAE national Sehamuddin Galadari, has discovered a novel structural modification in AMP-activated protein kinase (AMPK) during anticancer therapy that could pave the way for the development of more effective cancer treatments.

25 May 2022

Common prostate cancer medications may increase risk of serious metabolic or cardiovascular issues

Men taking either of the two most common oral medications for advanced prostate cancer who had also undergone hormone therapy to treat their disease were at higher risk of serious metabolic or cardiovascular issues than patients who were only receiving hormone therapy, Michigan Medicine researchers found.

25 May 2022

RED-D intervention reduces unplanned hospital readmissions for individuals with depressive symptoms

Results from a new study at Boston Medical Center show how transition support and post-discharge depression treatment reduce unplanned hospital readmissions for individuals with depressive symptoms.

25 May 2022

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

DNA mutations are essential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets.

25 May 2022

Lowering blood glucose levels could improve fertility in females with obesity

Reproductive hormone levels in females with obesity may be partially restored by lowering blood glucose levels, leading to improved fertility, according to a study published in the Journal of Endocrinology.

25 May 2022

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

Researchers assessed deep learning workflows involved in CT scans of COVID-19.

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Living in areas with high social vulnerability associated with worse outcomes after traumatic injury

Traumatic injuries - such as physical injuries resulting from a car accident, fall, gunshot or stabbing - are one of the most common causes of impairment and disability worldwide.

24 May 2022

Hydration restores airway integrity in people with cystic fibrosis

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure.

24 May 2022

Therapy News and Research

Combined treatment approach proves to be beneficial for prostate cancer patients

Children from historically marginalized groups or poor backgrounds less likely to survive neuroblastoma

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Aston University’s new antibiotic combination forms part of a lifesaving treatment for cystic fibrosis

Multidisciplinary care improves outcomes from chronic kidney disease

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

Common type 2 diabetes medication could be the key to improving fertility in women with obesity

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

NYU Abu Dhabi research could pave the way for more effective cancer treatments

Common prostate cancer medications may increase risk of serious metabolic or cardiovascular issues

RED-D intervention reduces unplanned hospital readmissions for individuals with depressive symptoms

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

Lowering blood glucose levels could improve fertility in females with obesity

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Study unveils the novel driver of cardiomyocyte loss

Living in areas with high social vulnerability associated with worse outcomes after traumatic injury

Hydration restores airway integrity in people with cystic fibrosis

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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