Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Case Western Reserve University researchers studying prions - misfolded proteins that cause lethal incurable diseases - have identified for the first time surface features of human prions responsible for their replication in the brain.

18 Jun 2021

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

UCLA Health will receive a $4.8 million grant from The National Institutes of Health to develop methods that will improve genetic risk estimates - polygenic risk scores - for specific diseases in people from diverse populations and mixed ancestries.

16 Jun 2021

Studies shed new light on disease processes in tuberculosis

Two new studies have cast unprecedented light on disease processes in tuberculosis, identifying key genetic changes that cause damage in the lungs and a drug treatment that could speed up recovery.

16 Jun 2021

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

The Southwest National Primate Research Center at Texas Biomedical Research Institute has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026.

15 Jun 2021

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

LSU Health New Orleans has been awarded $2.38 million in funding to lead partnerships to sequence SARS-CoV-2 variants.

14 Jun 2021

Delays and shortages hit SARS-CoV-2 genomic surveillance program

A new study from the Institute of Bioinformatics and Applied Biotechnology (IBAB), Bengaluru, India, provides an overview of how well this important monitoring mechanism is functioning around the world. The team has released their findings as a preprint on the bioRxiv* server.

14 Jun 2021

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

A recent study by researchers in Canada shows how mutations in newly emerging lineages of SARS-CoV-2 may disrupt the sequencing process and thus interfere with this important area of research.

14 Jun 2021

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

An inter-university research group has succeeded in constructing the gene expression network behind the vascular development process in plants.

11 Jun 2021

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care

11 Jun 2021

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

In the largest study of its kind to date, researchers analyzing national data from more than 63,000 patients with cancer and a positive COVID-19 diagnosis report an increased risk of death among those who were older, male, had a higher number of comorbidities, and had hematologic cancers and recent chemotherapy treatments.

11 Jun 2021

The potential of mRNA vaccines for a wide range of diseases

A new review article published in the journal Briefings in Functional Genomics focuses on the general characteristic features and mechanisms of mRNA vaccines. Further, this review has summarized the current progress of mRNA vaccines that have been developed for wide-ranging diseases, including COVID-19 disease.

8 Jun 2021

Measuring how patterns of gene expression change in children may help predict T1D progression

Type 1 diabetes (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys healthy pancreatic islet β cells, resulting in a lack of insulin.

7 Jun 2021

Study shows how different microbiomes could be harnessed to boost human health

There's a lot of interest right now in how different microbiomes--like the one made up of all the bacteria in our guts--could be harnessed to boost human health and cure disease.

7 Jun 2021

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Children's Hospital Los Angeles has been awarded a $2 million grant from the state of California to study a precision medicine approach to screening children for adverse childhood experiences.

3 Jun 2021

Epigenetic regulation affects the 3D structure of genome

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

3 Jun 2021

Study provides new knowledge about molecular mechanisms underlying human traits, diseases

A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge to the understanding of human complex traits and diseases.

1 Jun 2021

New method helps identify rare genetic disease that affects brain development

Rare disease experts detail the first results of an unprecedented collaboration to diagnose people living with unsolved cases of rare diseases across Europe.

1 Jun 2021

Could a mathematical application of information theory identify and predict SARS-CoV-2 mutations?

An interesting new study by researchers at the University of Portsmouth, UK, describes the use of a mathematical method to sequence genomes based on information theory. The method offers an alternative to clinical techniques, allowing mutations to be detected and possibly even predicted. In this way, it opens new research opportunities in bioinformatics and genetics.

31 May 2021

Inflammatory brain injury higher in men with acute COVID-19, finds study

The COVID-19 pandemic has been associated with both short- and long-term neurologic complications, including stroke, brain fog and persistent tiredness. A new study concludes that the effects of SARS-CoV-2 on the central nervous system (CNS) are due to the endothelial injury and inflammation that this produces in the brain.

31 May 2021

Bioinformatics News and Research

Further Reading

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

Studies shed new light on disease processes in tuberculosis

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

Delays and shortages hit SARS-CoV-2 genomic surveillance program

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

The potential of mRNA vaccines for a wide range of diseases

Measuring how patterns of gene expression change in children may help predict T1D progression

Study shows how different microbiomes could be harnessed to boost human health

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Epigenetic regulation affects the 3D structure of genome

Study provides new knowledge about molecular mechanisms underlying human traits, diseases

New method helps identify rare genetic disease that affects brain development

Could a mathematical application of information theory identify and predict SARS-CoV-2 mutations?

Inflammatory brain injury higher in men with acute COVID-19, finds study

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