Central Nervous System News and Research

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How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

Keys to maintaining good brain health

Your brain is pretty fabulous. Around 100 billion nerve cells work together to keep you nimble and quick in your thinking.

22 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

SARS-CoV-2 generates amyloid in cerebral spinal fluid

In a recent study posted to the bioRxiv* preprint server, an international team of researchers demonstrated amyloid aggregation due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cerebrospinal fluid (CSF).

20 Sep 2022

Research reveals the role of microglia-neuron connections during brain development

The Laboratory of Neuroimmunology of the Institute of Experimental Medicine, Budapest, Hungary, led by Ádám Dénes, describes the presence of a direct interaction site between microglial cells and the cell body of developing neurons, and reveals its role during brain development.

20 Sep 2022

Study identifies common genetic variants associated with musical beat synchronization

The first large-scale genomic study of musicality - published on the cover of today's Nature Human Behaviour - identified 69 genetic variants associated with beat synchronization, meaning the ability to move in synchrony with the beat of music.

19 Sep 2022

United States joins 30 other countries with circulating vaccine-derived poliovirus

CDC today announced that polioviruses found in New York, both from the case of paralytic polio in an unvaccinated adult in Rockland County and in several wastewater samples from communities near the patient's residence, meet the World Health Organization (WHO)'s criteria for circulating vaccine-derived poliovirus (cVDPV) – meaning that poliovirus continues to be transmitted in Rockland County, NY, and surrounding areas.

19 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

Study investigates link between plasma miRNAs and cognitive function among cognitively normal men

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 17, entitled, "Extracellular microRNA and cognitive function in a prospective cohort of older men: The Veterans Affairs Normative Aging Study."

15 Sep 2022

Scientists develop and test a new model of traumatic brain injury in zebrafish

A group of scientists, which included researchers from the Ural Federal University (UrFU), have developed and successfully tested a new model of traumatic brain injury (TBI) in zebrafish.

15 Sep 2022

SARS-CoV-2 viral infection is associated with an increased risk of Alzheimer’s disease

Older people who were infected with COVID-19 show a substantially higher risk - as much as 50% to 80% higher than a control group - of developing Alzheimer's disease within a year, according to a study of more than 6 million patients 65 and older.

14 Sep 2022

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

Up to three quarters of patients receiving cancer chemotherapy suffer from "chemo brain" - a long-term side effect that makes it harder to remember things, maintain attention, and learn new information. When it strikes children, whose brains are still developing, their schoolwork and self-esteem may suffer.

13 Sep 2022

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Newly released results from the Phase III ADAURA trial reveal that osimertinib yielded a 5.5-year median disease-free survival in the post-surgical treatment of patients with EGFR-mutated lung cancer, and nearly three in four patients treated with adjuvant osimertinib were disease-free at four years.

12 Sep 2022

Brain injury a common consequence of both COVID-19 and influenza

In a recent study published in the journal Brain, researchers reported that brain injury is common in coronavirus disease 2019 (COVID-19) and influenza.

12 Sep 2022

New research project investigates molecular mechanisms underlying NeuroCOVID

Infections with the coronavirus SARS-CoV-2 can trigger both temporary and long-term neurological and neuropsychiatric symptoms, severely impacting patients and the wider society.

9 Sep 2022

Kessler Foundation receives grant to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program

John DeLuca, PhD, senior vice president of research and training at Kessler Foundation, received a five-year, $468,019 grant from the National Multiple Sclerosis Society to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program.

9 Sep 2022

Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

Scientists at the Icahn School of Medicine at Mount Sinai in New York, the National Center for Advancing Translational Sciences (NCATS), and elsewhere have reversed the effects of several life-threatening inherited neurodegenerative diseases called lysosomal storage disorders (LSDs) in patient cells and mice.

9 Sep 2022

Significantly enlarged gray matter volume in neuropsychiatric long-COVID syndrome

In a recent study published in the journal Psychiatry Research, researchers found larger gray matter volumes (GMVs) in patients with neuropsychiatric long COVID syndrome.

8 Sep 2022

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.

8 Sep 2022

Central Nervous System News and Research

How smallpox and monkeypox viruses affect the nervous system

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Keys to maintaining good brain health

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

SARS-CoV-2 generates amyloid in cerebral spinal fluid

Research reveals the role of microglia-neuron connections during brain development

Study identifies common genetic variants associated with musical beat synchronization

United States joins 30 other countries with circulating vaccine-derived poliovirus

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

Study investigates link between plasma miRNAs and cognitive function among cognitively normal men

Scientists develop and test a new model of traumatic brain injury in zebrafish

SARS-CoV-2 viral infection is associated with an increased risk of Alzheimer’s disease

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Brain injury a common consequence of both COVID-19 and influenza

New research project investigates molecular mechanisms underlying NeuroCOVID

Kessler Foundation receives grant to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program

Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

Significantly enlarged gray matter volume in neuropsychiatric long-COVID syndrome

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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