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Scientists identify STING switch driving inflammation in Alzheimer’s disease

The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in Alzheimer's disease, those immune cells are chronically overactivated, causing inflammation that damages the connections between brain cells.

24 Apr 2026

Elevated Lp(a) levels associated with residual cardiovascular risk

New data analyzing more than 20,000 patients from three major NIH studies show that elevated Lipoprotein(a) [Lp(a)] is associated with residual cardiovascular risk and warrants aggressive risk reduction.

24 Apr 2026

Long-term study supports tenofovir alafenamide for chronic hepatitis B

Tenofovir alafenamide (TAF) has demonstrated comparable efficacy to tenofovir disoproxil fumarate (TDF), with improved renal and bone safety, in Chinese participants with chronic hepatitis B enrolled in two Phase 3 trials.

24 Apr 2026

Scientists identify new inflammatory mechanism to treat chronic health conditions

A protein long understood to drive inflammation by producing nitric oxide has a second, previously unknown role - it physically binds to another key protein inside cells to directly modulate the immune response.

24 Apr 2026

Drinking coffee alters your microbiome, mood, and memory

Coffee consumption influences the microbiota-gut-brain axis, affecting cognitive performance and emotional regulation through complex biological pathways.

24 Apr 2026

Heatwaves and coldwaves linked to increase in major cardiovascular events

Heatwaves and coldwaves are associated with increases in major cardiovascular events that are exacerbated by air pollution.

24 Apr 2026

The Big Catch-Up reaches millions of children with life-saving vaccines

The Big Catch-Up (BCU), a historic multi-year, multi-country effort to address vaccination declines driven largely by the COVID-19 pandemic, has reached an estimated 18.3 million children aged 1 to 5 across 36 countries with more than 100 million doses of life-saving vaccines, helping to narrow critical immunity gaps, announced Gavi, the Vaccine Alliance (Gavi), WHO, and UNICEF at the start of World Immunization Week.

24 Apr 2026

Type 1 diabetes preserves fitness but alters oxygen use in teens

The study highlights early microvascular impairment in adolescents with type 1 diabetes, emphasizing the importance of monitoring vascular health in this group.

24 Apr 2026

Children with multiple chronic conditions show unique antibiotic exposure patterns

A new study from Boston Children's Hospital found that annual prescription rates increased non-linearly as children's underlying level of medical complexity increased. Frequent antibiotic use has associated risks, including increased likelihood of antibiotic-related complications (e.g., C. difficile) as well as the development of antibiotic resistance. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.

24 Apr 2026

Study highlights gaps in opioid use disorder care during pregnancy

Opioid use disorder during pregnancy remains a critical yet under-addressed public health issue in the U.S., according to a new study at Columbia University Mailman School of Public Health.

23 Apr 2026

APOLLO AI learns from 25 billion medical events to predict future disease

APOLLO is a multimodal temporal foundation model trained on 25.2 billion medical events from 7.2 million patients across 33 years of Mass General Brigham records, integrating 28 medical modalities into unified “virtual patient representations.” Across 322 downstream tasks, the model showed strong performance in disease prediction, treatment-response stratification, hospital operations, and patient retrieval, supporting the idea of more computable, data-driven medicine.

23 Apr 2026

Microplastics in the liver may drive global liver disease rates

There is considerable evidence that microplastics and nanoplastics are present in the livers of humans, and wild animal populations on land and in the ocean.

23 Apr 2026

Late-night eating may amplify the effects of stress on gut health

It's well known that chronic stress can disrupt bowel function, sending people running to the bathroom or making them constipated.

23 Apr 2026

Legume and soy consumption may improve COPD symptoms

Consuming legumes and soy-based foods may help improve symptoms of chronic obstructive pulmonary disease (COPD) by reducing inflammation and irritation, according to a new study in the March 2026 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open access journal.

23 Apr 2026

Severe strokes significantly increase the risk of progressive dementia

As stroke severity increases, the risk of progressive cognitive decline and dementia substantially escalates, according to a national study led by Michigan Medicine researchers.

23 Apr 2026

Transcatheter arterialization of the deep veins improves quality of life for no-option CLTI patients

Data from the PROMISE III trial suggest that chronic limb-threatening ischemia (CLTI) patients with no other treatment options experienced significant quality of life (QoL) improvements after undergoing transcatheter arterialization of the deep veins (TADV).

23 Apr 2026