Neurodegenerative Disease News and Research

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Aquinnah Pharmaceuticals wins NINDS grant to advance novel therapies for ALS

Aquinnah Pharmaceuticals, leaders in stress granule biology, an exciting new target for the development of neurodegenerative therapeutics, announced today that it has been awarded $3.4 million from the National Institute of Neurological Disorders and Stroke in a competing grant to advance novel therapeutic drug candidates towards the clinic for treating patients with amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

21 Jun 2018

Researchers employ nucleotide-based gene silencing to mitigate common ataxia

In what researchers are calling a game changer for future ataxia treatments, a new study showed the ability to turn down the disease progression of the most common dominantly inherited ataxia.

20 Jun 2018

New robotic system can diagnose neurodegenerative diseases through eye movements

A new robotic system developed by UPM researchers and AURA Innovative Robotics Company can help diagnose neurodegenerative diseases, such as dementia and Parkinson, through the analysis of eye movements.

13 Jun 2018

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

AbCellera Biologics Inc. today announced the successful completion of the first phase of its collaboration with Denali Therapeutics Inc.

12 Jun 2018

Scientists find key biomarker of Parkinson's disease in the retina

A research involving scientists from the University of Alicante and the United States notes that the accumulation of a protein known as alpha-synuclein in the retina is a key Parkinson's biomarker that could help detect the degree of severity of the disease.

8 Jun 2018

Study: People taking immunosuppressant drugs less likely to develop Parkinson's disease

People who take drugs that suppress the immune system are less likely to develop Parkinson's disease, according to a study from Washington University School of Medicine in St. Louis.

31 May 2018

UTSA scientists explore stuttering and develop new technology to optimize brain function

A team of researchers at The University of Texas at San Antonio received a two-year, $387,000 grant, from the National Institutes of Health (NIH), to develop technology that will identify brain activity patterns that contribute to stuttering and use that technology to train people how to optimize brain functions.

31 May 2018

NIH summit presents recommendations to accelerate treatment development for Alzheimer's disease

Experts from government, academia, industry, non-profit organizations put forward recommendations that provide a roadmap for an integrated, multidisciplinary research agenda necessary to inform priorities for Alzheimer's disease and related dementias.

26 May 2018

Study identifies new mechanism involved in development of Lou Gehrig's disease

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig's disease, or amyotrophic lateral sclerosis.

23 May 2018

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein thus works for good and for bad.

23 May 2018

New study reveals the extent of brain damage due to elevated homocysteine

The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism.

17 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

New study to explore link between diet, intestinal microbiota and cognitive decline

Are abnormal intestinal microorganisms a risk factor for developing cognitive impairment? Researchers at Rush University Medical Center are trying to answer that question with a new study that will explore how the intestinal microbiota – the bacteria in the intestine –influence the progression of cognitive decline and the development of Alzheimer's disease.

14 May 2018

Study: Different strains of same protein may contribute to different Parkinson's-related brain disorders

Different Parkinson's-related brain disorders, called synucleionpathies, are characterized by misfolded proteins embedded in cells.

10 May 2018

Rehabilitation technique for stroke appears beneficial for multiple sclerosis patients

A rehabilitation technique originally developed for stroke has now been shown to also be effective for improving function for people with multiple sclerosis, a neurodegenerative disease.

24 Apr 2018

Newly developed drug compound may help treat Charcot-Marie-Tooth disease

Scientists have developed a new drug compound that shows promise as a future treatment for Charcot-Marie-Tooth disease, an inherited, often painful neurodegenerative condition that affects nerves in the hands, arms, feet and legs.

20 Apr 2018

Large ALS-causing protein aggregates protect rather than harm neurons

Scientists at the UNC School of Medicine have made a significant advance in the understanding of the complex and fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

17 Apr 2018

Novel disease model for ALS and MS can be used to develop new immunotherapies

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology.

16 Apr 2018

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.