Polymerase News and Research

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SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules.

21 Dec 2022

What are the characteristics of misdiagnosed human mpox cases?

In a recent study, researchers characterized overlooked cases of monkeypox (MPX).

21 Dec 2022

Withdrawal of COVID-19 mitigation measures resulted in a rebound in Streptococcus pneumoniae cases in Germany

Researchers from Germany conducted a population-based surveillance study to ascertain the etiology of community acquired pneumonia (CAP) during the re-emergence of viral and bacterial respiratory diseases after the relaxation of coronavirus disease 2019 (COVID-19) containment and mitigation measures.

20 Dec 2022

The potential effects of receiving 2 SARS-CoV-2 vaccine doses on household transmission in England

Researchers assessed the effects of two-dose COVID-19 vaccinations on household SARS-CoV-2 transmission among British residents.

20 Dec 2022

Seroprevalence measurements reveal a higher incidence of asymptomatic SARS-CoV-2 infections among residents of three federal German states

Researchers measured the seroprevalence against SARS-CoV-2 in blood donors from the states of Hesse, Lower Saxony, and North Rhine-Westphalia in Germany to determine the incidence of undetected asymptomatic SARS-CoV-2 infections.

20 Dec 2022

Study finds a lower mortality rate among individuals with myocarditis after mRNA vaccination than those with viral infection–related myocarditis

Researchers compared the prognosis of myocarditis developing after BNT162b2 mRNA COVID-19 vaccination with viral myocarditis over six months.

20 Dec 2022

Active transmission of Bourbon virus in New York

A recent study published in Emerging Infectious Diseases reported on the bourbon virus (BRBV) transmission in New York.

20 Dec 2022

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

Researchers reported on the vaccine effectiveness of a bivalent vaccine booster administered after ≥2.0 doses of monovalent mRNA vaccines against COVID-19–related hospitalizations among adult individuals 65.0 years or older.

20 Dec 2022

First H5N3 infection in a captive emperor tamarin documented in new study

In a new study, researchers reported the first H5N3 infection in a captive Emperor Tamarin.

19 Dec 2022

Exploring microstructural brain abnormalities after mild COVID-19

Researchers assessed the functional and microstructural brain abnormalities, tiredness, and cognitive impairment after mild coronavirus disease 2019 (COVID-19).

19 Dec 2022

Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Researchers used a multi-modal approach to examine the types, prevalence, and relevance of sleep disturbance in individuals hospitalized with COVID-19 and determine associations between dyspnea and sleep disturbance.

19 Dec 2022

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Researchers investigated whether coronavirus disease 2019 (COVID-19)-associated chemosensory alterations were predictive of serological responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among United States (US) residents.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus.

16 Dec 2022

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Researchers used serological measurements from a longitudinal cohort to evaluate the use of binding antibodies against the SARS-CoV-2 spike protein receptor binding domain as correlates of protection against the immune evasive Omicron subvariants BA.1 and BA.2.

16 Dec 2022

Polymerase News and Research

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

What are the characteristics of misdiagnosed human mpox cases?

Withdrawal of COVID-19 mitigation measures resulted in a rebound in Streptococcus pneumoniae cases in Germany

The potential effects of receiving 2 SARS-CoV-2 vaccine doses on household transmission in England

Seroprevalence measurements reveal a higher incidence of asymptomatic SARS-CoV-2 infections among residents of three federal German states

Study finds a lower mortality rate among individuals with myocarditis after mRNA vaccination than those with viral infection–related myocarditis

Active transmission of Bourbon virus in New York

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

First H5N3 infection in a captive emperor tamarin documented in new study

Exploring microstructural brain abnormalities after mild COVID-19

Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

The mpox viral load kinetics over time in various parts of the body

Study reports that delaying surgery post-COVID-19 reduces the risk of postoperative cardiovascular issues

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

mRNA vaccine methodologies: Production, value and spectrometer use

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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