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International team explores genetic diversity of Plasmodium vivax in the Americas

Human migrations - from the prehistoric epoch to the present day - have extended cultures across the globe. With these travelers have come unwanted stowaways: mosquito-borne parasites belonging to the Plasmodium species - a group responsible for malaria, worldwide.

12 Jul 2013

Choline consumption improves long-term memory and attention-holding capacity

An experimental study in rats has shown that consuming choline, a vitamin B group nutrient found in foodstuffs like eggs and chicken or beef liver, soy and wheat germ, helps improve long-term memory and attention-holding capacity.

12 Jul 2013

Scientists set out to develop safer versions of acetaminophen

Efforts to develop a safer form of acetaminophen - the pain and fever-reducer that is one of the most widely used drugs - have led to discovery of substances that may have less potentially toxic effects on the liver. A report on the research appears in ACS Medicinal Chemistry Letters.

12 Jul 2013

Researchers develop new model for more equitable allocation of livers for transplantation

Using the same type of mathematical formulas used to draw political redistricting maps, Johns Hopkins researchers say they have developed a model that would allow for the more equitable allocation of livers from deceased donors for transplantation.

12 Jul 2013

Comprehensive analysis of disease burden in US

In nearly every major cause of premature death - from ischemic heart disease to diabetes to interpersonal violence - the United States trails its economic peers, according to new research from a global collaborative of scientists led by the Institute for Health Metrics and Evaluation at the University of Washington.

12 Jul 2013

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive top-line results from its ongoing Phase I trial of ALN-TTRsc, a subcutaneously administered RNAi therapeutic targeting the transthyretin gene for the treatment of TTR-mediated amyloidosis.

12 Jul 2013

Research reveals link between elevated BMI and increased risk of gallstone in women

New research reveals a causal association between elevated body mass index (BMI) and increased risk of gallstone disease. Results published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show women are at greater risk of developing gallstones.

12 Jul 2013

Heart transplant could get a second chance to save life

Human hearts which are not used each year because they are deemed unsuitable for an organ transplant could get a second chance to save a life, with the help of new research taking place in the North East.

11 Jul 2013

Acetaminophen overdose survivors have lower overall health following acute liver failure

Spontaneous survivors of acetaminophen overdose have significantly lower overall health compared to survivors or transplant recipients following acute liver failure caused by non-drug induced liver injury according to a new study published online in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

10 Jul 2013

Researchers discover new class of antimalarial compounds

Despite renewed global efforts for eradication, malaria continues to exert devastating effects on human health. An estimated 220 million people are infected each year by malaria-causing Plasmodium parasites, which are transmitted by the bite of an infected mosquito. This enormous infection burden leads to some 660,000 lives lost to malaria each year, the majority of these young children in sub-Saharan Africa. While a vaccine to prevent malaria remains elusive, we depend on antimalarial compounds both to treat infections and prevent disease.

10 Jul 2013

New approach delivers RNA drugs to silence malfunctioning genes

Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference.

10 Jul 2013

TGA of Australia approves Vertex Pharmaceuticals' KALYDECO for cystic fibrosis

Vertex Pharmaceuticals Incorporated today announced that the Therapeutic Goods Administration of Australia has approved KALYDECO (ivacaftor) for people with cystic fibrosis ages 6 and older who have at least one copy of the G551D mutation in the cystic fibrosis transmembrane conductance regulator gene.

10 Jul 2013

UIC to manage largest-ever prospective health study of Hispanic/Latino population

The University of Illinois at Chicago Institute for Minority Health Research will manage a National Institutes of Health project to follow up, over the next six years, all Chicago participants in the Hispanic Community Health Study/Study of Latinos—the largest-ever prospective health study of this population.

9 Jul 2013

Soy peptide injection dramatically reduces colon cancer metastasis in mice

After a recent University of Illinois study showed that injection of the soy peptide lunasin dramatically reduced colon cancer metastasis in mice, the researchers were eager to see how making lunasin part of the animals' daily diet would affect the spread of the disease.

9 Jul 2013

Continental Who's Who recognizes Douglas M. Weissman as a Pinnacle Professional

Dr. Douglas M. Weissman, MD, FACP is recognized by Continental Who's Who as a Pinnacle Professional in the field of Medicine. As a gastroenterologist in private practice since 1993, Dr. Weissman specializes in the treatment of all gastrointestinal, biliary and liver disease problems.

6 Jul 2013

State highlights: Docs prescribe narcotics too often, CDC chief says; Fla. hospices get close scrutiny; Calif. Medi-Cal provider rate bump delayed

The nation's top public health official on Tuesday sharply criticized the widespread treatment of aches and pains with narcotics, saying that doctors are prescribing such drugs too soon, too often and for too long -- putting patients at risk of addiction and overdose. Dr. Tom Frieden, director of the U.S. Centers for Disease Control and Prevention, said that doctors are relying on these powerful drugs to treat chronic pain when physical therapy, exercise and other remedies would be safer and in many cases more effective (Girion and Glover, 7/2).

4 Jul 2013

CEA-Leti receives €1M from bpifrance to accelerate the development of liver-cancer detection system

CEA-Leti announced today €1 million in funding from bpifrance to accelerate preclinical development of a liver-cancer detection system called LipImage 815™.

4 Jul 2013

First Edition: July 3, 2013

Today's headlines detail the Obama administration announcement that it would delay the health law rule requiring businesses provide insurance to workers.

3 Jul 2013

Endoscopic imaging: an interview with Len Farris, Vice President of Marketing, Americas, PENTAX Medical

The impact of endoscopic imaging on patient care has been enormous since the first fiber optic systems were introduced more than 50 years ago. Today, high resolution and high definition systems are used to provide clinicians and patients unprecedented images from inside the body.

From PENTAX Medical Company 3 Jul 2013

Nearly half a million dollars given to physicians working to cure psoriatic diseases

Twelve residents and medical students each received a one-year, $40,000 National Psoriasis Foundation fellowship to study psoriasis and psoriatic arthritis.

3 Jul 2013

Liver News and Research

International team explores genetic diversity of Plasmodium vivax in the Americas

Choline consumption improves long-term memory and attention-holding capacity

Scientists set out to develop safer versions of acetaminophen

Researchers develop new model for more equitable allocation of livers for transplantation

Comprehensive analysis of disease burden in US

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Research reveals link between elevated BMI and increased risk of gallstone in women

Heart transplant could get a second chance to save life

Acetaminophen overdose survivors have lower overall health following acute liver failure

Researchers discover new class of antimalarial compounds

New approach delivers RNA drugs to silence malfunctioning genes

TGA of Australia approves Vertex Pharmaceuticals' KALYDECO for cystic fibrosis

UIC to manage largest-ever prospective health study of Hispanic/Latino population

Soy peptide injection dramatically reduces colon cancer metastasis in mice

Continental Who's Who recognizes Douglas M. Weissman as a Pinnacle Professional

State highlights: Docs prescribe narcotics too often, CDC chief says; Fla. hospices get close scrutiny; Calif. Medi-Cal provider rate bump delayed

CEA-Leti receives €1M from bpifrance to accelerate the development of liver-cancer detection system

First Edition: July 3, 2013

Endoscopic imaging: an interview with Len Farris, Vice President of Marketing, Americas, PENTAX Medical

Nearly half a million dollars given to physicians working to cure psoriatic diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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