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Abbott RealTime HCV Genotype II assay receives FDA approval

The U.S. Food and Drug Administration today approved a test that identifies the genotype of hepatitis C virus that a patient is carrying. The Abbott RealTime HCV Genotype II, which can differentiate genotypes 1, 1a, 1b, 2, 3, 4, and 5,using a sample of an infected patient's blood plasma or serum, will aid health care professionals in determining the appropriate approach to treatment.

21 Jun 2013

Gene switch off may increase risk of heart and blood vessel disease: Research

Risk of heart and blood vessel disease may increase when a particular gene is switched off, according to preliminary research presented at the American Heart Association's Emerging Science Series Webinar.

20 Jun 2013

New study shows that dietary fructose causes liver damage even without weight gain

The role of dietary fructose in the development of obesity and fatty liver diseases remains controversial, with previous studies indicating that the problems resulted from fructose and a diet too high in calories.

20 Jun 2013

LDL cholesterol blood levels: an interview with Dr. Harvey Kaufman

What is LDL cholesterol? What blood level of LDL cholesterol is considered optimal and why are high levels of LDL cholesterol a key marker of death risk from heart disease? Dr. Harvey Kaufman, senior medical director of Quest Diagnostics gives us some answers.

From Quest Diagnostics 19 Jun 2013

Scientists discover new mechanism to protect body from harmful bacteria

Scientists at the University of Calgary's Faculty of Medicine have discovered a mechanism that is used to protect the body from harmful bacteria. Platelets, a component of blood typically associated with clotting, were discovered to actively search for specific bacteria, and upon detection, seal it off from the rest of the body. The findings, which were published in Nature Immunology this week, provide the science community with a greater understanding of immunity.

19 Jun 2013

FGF21 endocrine hormone which reduces glucose levels also protects against cardiac diseases in mice

A research group has found that FGF21, an endocrine factor which reduces glucose levels, protects against cardiac diseases in mice. The research, published online on the journal Nature Communications, was led by Francesc Villarroya, professor from the Department of Biochemistry and Molecular Biology of the UB and Director of the Institute of Biomedicine of the University of Barcelona (IBUB), affiliated centre with the campus of international excellence BKC.

18 Jun 2013

Certain gastrointestinal types of GVHD are associated with worsened quality of life and death

Joseph Pidala, M.D., M.S., assistant member of the Blood and Bone Marrow Transplant and Immunology programs at Moffitt Cancer Center, and colleagues from the Chronic Graft-Versus-Host Disease Consortium have determined that certain gastrointestinal and liver-related types of chronic graft-versus-host disease (GVHD) are associated with worsened quality of life and death.

18 Jun 2013

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.

18 Jun 2013

Investigators recruit subjects for Boston Children's Hand Transplant Program

Boston Children's Hospital today announced that investigators are now recruiting subjects for the world's first pediatric hand transplant program. The Boston Children's Hand Transplant Program, led by principal investigator Amir Taghinia, MD, and William Harmon, MD, is a research-based program that will offer bi-lateral hand transplants for children living without two functioning hands.

17 Jun 2013

New research reports that UnaG protein could lead to new liver test

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

17 Jun 2013

Study demonstrates efficacy of canakinumab at tapering corticosteroid use in patients with SJIA

Study findings first presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate the efficacy of canakinumab at tapering corticosteroid (CS) use in patients with SJIA.

14 Jun 2013

Research findings could enable early screening of HCC patients for more aggressive treatment

Latest research findings by scientists at the Cancer Science Institute of Singapore at the National University of Singapore could enable early screening of patients with hepatocellular carcinoma, a major form of liver cancer, for more aggressive treatment to improve survival rate.

14 Jun 2013

Study: Tocilizumab is effective in children with juvenile idiopathic arthritis

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism shows that tocilizumab is efficacious and leads to a sustained clinically meaningful improvement in children with polyarticular Juvenile Idiopathic Arthritis (pcJIA).

13 Jun 2013

Research could enable early screening of liver cancer patients to improve survival rate

Latest research findings by scientists at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) could enable early screening of patients with hepatocellular carcinoma (HCC), a major form of liver cancer, for more aggressive treatment to improve survival rate.

13 Jun 2013

Society of Interventional Radiology releases Updates in Interventional Radiology 2013

The Society of Interventional Radiology announces the release of "Updates in Interventional Radiology 2013," a concise reference of the current literature most relevant to the specialty.

13 Jun 2013

Constella® (linaclotide), for the symptomatic treatment of Irritable Bowel Syndrome with Constipation (IBS-C), is now available in Germany, UK and Nordic countries

Almirall, S.A. (ALM:MC) and Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) announced the launch of Constella® (linaclotide 290mcg capsules once daily), the first approved prescription therapy in a new class of treatments for adults suffering from moderate to severe IBS-C,(1) in Europe. Constella® is now available in Germany, the UK and Nordic countries and is expected to be launched in several other European countries in 2013.

13 Jun 2013

Investigational all-oral interferon-free combination from Boehringer Ingelheim achieves 95% viral cure rates in genotype-1b hepatitis C patients

New data from Boehringer Ingelheim’s interferon-free SOUND-C3 study were presented during the APASL Liver Week in Singapore. The Phase IIb study investigated the efficacy and safety of faldaprevir+ and deleobuvir+ (BI 207127) plus ribavirin in treatment-naïve patients with genotype-1b (GT-1b) hepatitis C virus (HCV),1 one of the most common types of HCV globally.2

13 Jun 2013

Green coffee bean dietary supplements does not prevent weight gain in obese mice: Study

A major ingredient in those green coffee bean dietary supplements - often touted as "miracle" weight-loss products - doesn't prevent weight gain in obese laboratory mice fed a high-fat diet when given at higher doses.

13 Jun 2013

Effective method to restore sight to patients with blinding diseases

Researchers at the University of California, Berkeley, have developed an easier and more effective method for inserting genes into eye cells that could greatly expand gene therapy to help restore sight to patients with blinding diseases ranging from inherited defects like retinitis pigmentosa to degenerative illnesses of old age, such as macular degeneration

13 Jun 2013

Few cups of hot cocoa may help obese people better control inflammation-related diseases

A few cups of hot cocoa may not only fight off the chill of a winter's day, but they could also help obese people better control inflammation-related diseases, such as diabetes, according to Penn State researchers.

13 Jun 2013

Liver News and Research

Abbott RealTime HCV Genotype II assay receives FDA approval

Gene switch off may increase risk of heart and blood vessel disease: Research

New study shows that dietary fructose causes liver damage even without weight gain

LDL cholesterol blood levels: an interview with Dr. Harvey Kaufman

Scientists discover new mechanism to protect body from harmful bacteria

FGF21 endocrine hormone which reduces glucose levels also protects against cardiac diseases in mice

Certain gastrointestinal types of GVHD are associated with worsened quality of life and death

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Investigators recruit subjects for Boston Children's Hand Transplant Program

New research reports that UnaG protein could lead to new liver test

Study demonstrates efficacy of canakinumab at tapering corticosteroid use in patients with SJIA

Research findings could enable early screening of HCC patients for more aggressive treatment

Study: Tocilizumab is effective in children with juvenile idiopathic arthritis

Research could enable early screening of liver cancer patients to improve survival rate

Society of Interventional Radiology releases Updates in Interventional Radiology 2013

Constella® (linaclotide), for the symptomatic treatment of Irritable Bowel Syndrome with Constipation (IBS-C), is now available in Germany, UK and Nordic countries

Investigational all-oral interferon-free combination from Boehringer Ingelheim achieves 95% viral cure rates in genotype-1b hepatitis C patients

Green coffee bean dietary supplements does not prevent weight gain in obese mice: Study

Effective method to restore sight to patients with blinding diseases

Few cups of hot cocoa may help obese people better control inflammation-related diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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