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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

Research explores effects of cannabis use on males’ reproductive health

As legal access to marijuana continues expanding across the U.S., more scientists are studying the effects of its active ingredient, tetrahydrocannabinol (THC), in teens, adults and pregnant women.

19 Dec 2018

New compound blocks genetic cause of familial ALS and frontotemporal dementia

Since the ice bucket challenge went viral in 2014, raising awareness and funding for ALS research, scientists have learned much about a disease that disconnects muscles from nerves, leading to muscle atrophy and eventual death. Their ultimate goal is to create medications capable of stopping ALS in its tracks.

18 Dec 2018

New genetic testing method increases the precision of biomarker analysis

Estonian scientists have announced the invention of a genetic testing technology that allows the number of clinical biomarkers to be analyzed at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future.

18 Dec 2018

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance to the drugs.

18 Dec 2018

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

In biomedical research, plant breeding, and countless other endeavors, geneticists are on the hunt for the specific genes responsible for disease susceptibility, yield, and other traits of interest.

17 Dec 2018

New 'epigenetics-based' cervical cancer test outperforms Pap smear and HPV tests

A new test for cervical cancer was found to detect all of the cancers in a randomized clinical screening trial of 15,744 women, outperforming both the current Pap smear and human papillomavirus test at a reduced cost, according to a study led by Queen Mary University of London.

17 Dec 2018

New robust method for microscopically profiling tiny single cells

Many of the cell types in our bodies work in obscure ways, that science does not yet fully understand. That also goes for immune cells, which are vital for protecting us against serious diseases.

17 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Folate deficiency creates more damaging chromosomal abnormalities than previously known

Folate deficiency creates more problems in connection with DNA replication than researchers had hitherto assumed, researchers from the University of Copenhagen show in a new study.

14 Dec 2018

Researchers uncover microRNAs involved in the control of social behavior

The recent discovery of microRNAs as key regulators of biological processes has fueled an explosion of research activity into their function in health and disease.

14 Dec 2018

Geneticists discover how sex-linked disorders arise

Researchers have discovered a regulatory gene carried on the Y chromosome that determines whether a baby will be male or female and the risk of disease.

14 Dec 2018

Weakened metabolism of immune T cells may account for serious complications in elderly

The elderly suffer more serious complications from infections and benefit less from vaccination than the general population.

14 Dec 2018

Shining new light on neuron firing

Scientists have plenty of ways to watch as individual neurons in a brain fire, sending electrical signals from one to the next, but they all share a basic problem.

14 Dec 2018

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells.

14 Dec 2018

Scientists perform lung lavage as new approach for tuberculosis diagnosis in rhinoceros

Conventional immunological tests for tuberculosis in rhinoceros are substantially insecure and bear high risk of false negative or false positive diagnosis with sometimes fatal consequences for the animal.

13 Dec 2018

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

Recent findings on rare genetic disorder may help develop new treatment options

Fresh discoveries about a rare genetic disorder that affects mainly boys may inform the development of therapies to treat the condition.

13 Dec 2018

Unraveling the complexity of cancer biology can prompt new avenues for drug development

Unraveling the complexity of cancer biology can lead to the identification of new molecules involved in breast cancer and prompt new avenues for drug development. And proteogenomics, an integrated, multipronged approach, seems to be a way to do it.

13 Dec 2018

DNA News and Research

Further Reading

Active ingredient in eye drops shows promise for treating aggressive blood cancer

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Research explores effects of cannabis use on males’ reproductive health

New compound blocks genetic cause of familial ALS and frontotemporal dementia

New genetic testing method increases the precision of biomarker analysis

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

New 'epigenetics-based' cervical cancer test outperforms Pap smear and HPV tests

New robust method for microscopically profiling tiny single cells

Researchers reveal how key transcription factor keeps the immune system in check

Folate deficiency creates more damaging chromosomal abnormalities than previously known

Researchers uncover microRNAs involved in the control of social behavior

Geneticists discover how sex-linked disorders arise

Weakened metabolism of immune T cells may account for serious complications in elderly

Shining new light on neuron firing

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Scientists perform lung lavage as new approach for tuberculosis diagnosis in rhinoceros

New discovery will improve the safety and predictability of CRISPR

Recent findings on rare genetic disorder may help develop new treatment options

Unraveling the complexity of cancer biology can prompt new avenues for drug development

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