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Nanobodies from llamas could be used to deliver targeted medicines to human muscle cells

In "proof of concept" experiments with mouse and human cells and tissues, Johns Hopkins Medicine researchers say they have designed tiny proteins, called nanobodies, derived from llama antibodies, that could potentially be used to deliver targeted medicines to human muscle cells.

12 May 2022

Researchers identify cellular serpins as host factors that restrict SARS-CoV-2 infection

Researchers investigated differences in susceptibility between individuals and may have discovered a new opportunity for treatment.

12 May 2022

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

Researchers performed an unbiased evaluation of the early memory B cell repertoire specific for the Omicron and Delta variants of SARS-CoV-2.

12 May 2022

SK bioscience's typhoid vaccine licensed for export by Korean Ministry of Food and Drug Safety

The International Vaccine Institute (IVI) and SK bioscience announced today that SK bioscience obtained an export license from the Korean Ministry of Food and Drug Safety for SK's typhoid vaccine 'SKYTyphoid' which they jointly developed.

12 May 2022

Messenger RNA COVID-19 vaccines induce high levels of short-lived antibodies compared to natural infection

Researchers extensively investigated the dynamics of antibodies induced by natural SARS-CoV-2 infection and vaccination in Qatar's diverse population

12 May 2022

Research looks at potential of pantethine against SARS-CoV-2

In a recent study posted to the Research Square preprint server, researchers assessed the antiviral activity of pantethine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 May 2022

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

In a recent study published in the journal Molecular Therapy, researchers identified Bifonazole, an imidazole-based antifungal agent, to have potent activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using high-throughput screening of small molecules.

12 May 2022

Research describes how DNA damage can affect neural health and function

A new research paper in the journal EMBO Reports describes how DNA damage can affect neural health and function.

12 May 2022

Research may lead to more effective interventions for hypoxic-ischemic encephalopathy

One of the most common causes of disability or death in newborns is a lack of oxygen or blood flow in the brain during labor or delivery.

11 May 2022

Study shows link between abnormal blood clotting and impaired exercise capacity in people with long COVID

According to a study published today in Blood Advances, people suffering from long COVID may face an increased risk of abnormal blood clotting.

11 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Discovery of host co-factors necessary for SARS-CoV2 infection

A new study published in the journal EMBO Reports has reported on the shedding of two proteases, namely, ADAM10 and ADAM17, which aids in S protein-dependent molecular events.

11 May 2022

UC Davis researchers identify a protein that keeps Kaposi's sarcoma-associated herpesvirus dormant

A team of UC Davis researchers has identified a protein in the cancer cell's nucleus as a critical agent keeping Kaposi's sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body's immune system.

11 May 2022

Direct influenza infection of the heart drives cardiac complications, study reveals

Researchers have shown for the first time in mice that heart problems associated with the flu are not caused by raging inflammation in the lungs, as has long been predicted.

11 May 2022

Study shows efficacy of COVID-19 vaccine in people receiving cancer treatment

People undergoing active cancer treatment, including stem cell transplant, should receive the COVID-19 vaccine, according to a study published in JAMA Oncology.

11 May 2022

Unique binding property may explain the ability of delta variant to spread more rapidly

Unlike other SARS-CoV-2 variants, the Delta variant can attach to copies of itself, forming larger aggregations, or clumps, of viral particles, suggests a study by scientists at the National Institutes of Health.

11 May 2022

Researchers find gene that shapes mutation rate in mice

Every organism is born with a few mutations in their genome that differ genetically from both of their parents.

11 May 2022

Rutgers study identifies key protein for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, a finding that has important implications for brain health and future therapies for brain disorders.

11 May 2022

Study modeling tumor evolution reveals a central tradeoff that could be exploited for cancer treatment

Though the mutations accumulated by cancer cells occur more or less randomly, certain regions of genes essential to cancer growth appear to be more frequently mutated than others in established tumors.

11 May 2022

Children exposed to maltreatment present a response-to-stress pattern like that of adolescents

The acute psychosocial stress states stimulate the secretion of an antibody type protein which is decisive in the first immune defence against infection, but only after puberty. However, children with a history of maltreatment present a similar response to that of adolescents, which suggests there is an early maturation of the immune system in these cases.

11 May 2022

Protein C News and Research

Nanobodies from llamas could be used to deliver targeted medicines to human muscle cells

Researchers identify cellular serpins as host factors that restrict SARS-CoV-2 infection

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

SK bioscience's typhoid vaccine licensed for export by Korean Ministry of Food and Drug Safety

Messenger RNA COVID-19 vaccines induce high levels of short-lived antibodies compared to natural infection

Research looks at potential of pantethine against SARS-CoV-2

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

Research describes how DNA damage can affect neural health and function

Research may lead to more effective interventions for hypoxic-ischemic encephalopathy

Study shows link between abnormal blood clotting and impaired exercise capacity in people with long COVID

The promise of RNA medicine is targeted and personalized

Discovery of host co-factors necessary for SARS-CoV2 infection

UC Davis researchers identify a protein that keeps Kaposi's sarcoma-associated herpesvirus dormant

Direct influenza infection of the heart drives cardiac complications, study reveals

Study shows efficacy of COVID-19 vaccine in people receiving cancer treatment

Unique binding property may explain the ability of delta variant to spread more rapidly

Researchers find gene that shapes mutation rate in mice

Rutgers study identifies key protein for brain stem cell longevity

Study modeling tumor evolution reveals a central tradeoff that could be exploited for cancer treatment

Children exposed to maltreatment present a response-to-stress pattern like that of adolescents

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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