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Arrowhead seeks approval to start ARC-520 phase 2a trial for chronic hepatitis B infection

Arrowhead Research Corporation, a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it recently filed an application for approval to begin a phase 2a clinical trial of its RNAi-based therapeutic candidate, ARC-520, for the potential treatment of chronic hepatitis B virus infection.

25 Nov 2013

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Janssen Therapeutics, Division of Janssen Products, LP, announced today the U.S. Food and Drug Administration has approved OLYSIO (simeprevir), an NS3/4A protease inhibitor, for the treatment of chronic hepatitis C infection as part of an antiviral treatment regimen in combination with pegylated interferon and ribavirin in genotype 1 infected adults with compensated liver disease, including cirrhosis.

23 Nov 2013

Probe to measure immune function could lead to determine nanoparticle-based drugs for cancer patients

The development of a probe to measure the body's immune function could lead to more accurate, individualized doses for cancer patients prescribed nanoparticle-based drugs, according to research conducted at the University of North Carolina.

21 Nov 2013

Multiple sclerosis researchers receive NMSS drug development grant

A $500,000 drug development grant from the National Multiple Sclerosis Society was awarded to a partnership between a multiple sclerosis research team at the Icahn School of Medicine at Mount Sinai and Karyopharm Therapeutics Inc., a clinical stage pharmaceutical company. Dr. Patrizia Casaccia, MD, PhD, Professor in the Departments of Neuroscience and Genetics and Genomics, at Icahn School of Medicine at Mount Sinai, will be the academic lead.

21 Nov 2013

TSRI researchers solve structure of key protein in deadly, but little known virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses. Researchers at The Scripps Research Institute (TSRI) have now solved the structure of a key protein in the Nipah virus, which could pave the way for the development of a much-needed antiviral drug.

20 Nov 2013

Topokine initiates Phase 2 clinical trial of XAF5 Gel for double chin treatment

Topokine Therapeutics has initiated dosing in a Phase 2, randomized controlled clinical trial of XAF5 Gel for reduction of excess submental fat, commonly known as "double chin." XAF5 Gel is a proprietary skin formulation of a compound already known to reduce fat around the human eye. Study participants are applying XAF5 Gel or placebo once a night to skin under the chin.

20 Nov 2013

Scientists at Salk Institute develop novel platform to study kidney diseases

Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology.

19 Nov 2013

AGA, Covidien partner to improve lives of people struggling with digestive diseases

The American Gastroenterological Association Institute announced today that Covidien, a leading global provider of health-care products, recently agreed to expand its corporate grant to the AGA Institute.

19 Nov 2013

Atopix recruits first patient in OC459 Phase 2 trial for treatment of atopic dermatitis

Atopix Therapeutics Ltd, a biopharmaceutical company developing innovative CRTH2 antagonists for allergic disease, announced the recruitment of the first patient in a six month Phase 2 clinical trial of its lead compound OC459 in moderate-to-severe atopic dermatitis (eczema).

19 Nov 2013

University of Wisconsin scientist to present revolutionary stem cell technology to Australian bioindustry

Internationally recognised stem cell scientist, Associate ProfessorIgor Slukvin, University of Wisconsin – Madison, is visiting Australia as the key-note speaker at a Stem Cell Meeting and Workshop in Sydney next week.

19 Nov 2013

Layers of skin that form first line of defence in body's fight against infection reveal secret

The layers of skin that form the first line of defence in the body's fight against infection have revealed a unanticipated secret.

19 Nov 2013

Researchers solve structure of key protein in Nipah virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses.

18 Nov 2013

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Findings by scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna reveal a surprising role for histone deacetylase 1 (HDAC1) - a member of a family of chromatin modifying proteins - in the development of skin tumors.

18 Nov 2013

Researchers generate three-dimensional kidney structures from human stem cells

18 Nov 2013

Oraya presents data from INTREPID study of stereotactic radiotherapy for treatment of wet AMD

Oraya® Therapeutics, Inc. announced today that initial three-year safety follow-up data from its INTREPID study of Oraya Therapy™ stereotactic radiotherapy for the treatment of wet age-related macular degeneration (AMD) were presented for the first time today during the America Academy of Ophthalmology's (AAO) annual meeting in New Orleans.

16 Nov 2013

GoInformatics, TeselaGen form strategic partnership to offer cutting-edge biodesign automation tools

GoInformatics and TeselaGen have announced a strategic partnership to offer a state-of-the-art Biological Design Automation and Scientific Data Management platform. With a secure repository to collect, organize, and store research information, the integrated cloud-based platform will enable scientists advance their research at a much faster pace.

16 Nov 2013

Sorrento Therapeutics to acquire San Diego-based Concortis Biosystems

Sorrento Therapeutics, Inc. announced today the entry into a definitive agreement to acquire San Diego-based Concortis Biosystems, Corp. in a deal that provides Sorrento with a comprehensive technology platform for generation of antibody drug conjugates (ADC). Under the terms of the agreement dated November 11, 2013, subject to satisfaction of certain closing conditions, upon closing, Sorrento will issue an aggregate of 1,331,978 shares of its common stock to the Concortis shareholders.

14 Nov 2013

FDA approves ibrutinib for treatment of mantle cell lymphoma

Today's U.S. Food and Drug Administration approval of ibrutinib to treat patients with mantle cell lymphoma is a significant advance for patients with this blood cancer. It was approved as a single agent for treatment of patients with MCL who have received at least one prior therapy.

14 Nov 2013

Cedars-Sinai Phase I-II clinical trial may help combat recurrence of small cell lung cancer

Alain C. Mita, MD, is fighting an uphill battle against small cell lung cancer. Despite the severity of the disease, the standard-of-care treatment remains the same today as it was nearly 30 years ago.

14 Nov 2013

Neovasc's Tiara transcatheter mitral valve replacement technology gets US patent

Neovasc Inc. today announced that the first patent covering the company's innovative Tiara transcatheter mitral valve replacement technology has been issued by the US Patent and Trademark Office.

13 Nov 2013

Therapeutics News and Research

Arrowhead seeks approval to start ARC-520 phase 2a trial for chronic hepatitis B infection

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Probe to measure immune function could lead to determine nanoparticle-based drugs for cancer patients

Multiple sclerosis researchers receive NMSS drug development grant

TSRI researchers solve structure of key protein in deadly, but little known virus

Topokine initiates Phase 2 clinical trial of XAF5 Gel for double chin treatment

Scientists at Salk Institute develop novel platform to study kidney diseases

AGA, Covidien partner to improve lives of people struggling with digestive diseases

Atopix recruits first patient in OC459 Phase 2 trial for treatment of atopic dermatitis

University of Wisconsin scientist to present revolutionary stem cell technology to Australian bioindustry

Layers of skin that form first line of defence in body's fight against infection reveal secret

Researchers solve structure of key protein in Nipah virus

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Researchers generate three-dimensional kidney structures from human stem cells

Oraya presents data from INTREPID study of stereotactic radiotherapy for treatment of wet AMD

GoInformatics, TeselaGen form strategic partnership to offer cutting-edge biodesign automation tools

Sorrento Therapeutics to acquire San Diego-based Concortis Biosystems

FDA approves ibrutinib for treatment of mantle cell lymphoma

Cedars-Sinai Phase I-II clinical trial may help combat recurrence of small cell lung cancer

Neovasc's Tiara transcatheter mitral valve replacement technology gets US patent

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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