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Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

Collaborating with researchers from the Northwestern University Feinberg School of Medicine in Chicago, a research team at Wayne State University's School of Medicine led by Kezhong Zhang, Ph.D., has contributed to an important discovery in the inflammatory stress mechanism and specific inhibitor for the treatment of rheumatoid arthritis.

13 Nov 2013

International research consortium to focus on pediatric translational research

The Children's Hospital of Philadelphia CEO Steven M. Altschuler, Drexel University President John A. Fry, and Hebrew University of Jerusalem President Menahem Ben-Sasson signed a research agreement on November 11 as part of Philadelphia Mayor Michael A. Nutter's trade mission to Israel. The research partnership is designed to focus on pediatric translational research and to develop a collaborative platform for advancing pediatric medicine from the lab to the bedside.

13 Nov 2013

Orexigen Therapeutics reports net loss of $18.6 million in Q3 2013

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of obesity, today announced business and financial results for the third quarter ended September 30, 2013.

12 Nov 2013

BioGaia plans to invest in first phase of project aimed at developing drug for NEC

The board of BioGaia has decided to invest in the first phase of a long-term project aimed at developing a drug with rigorous hygiene, analysis and documentation requirements, to treat the highly fatal disease Necrotising Enterocolitis, which affects premature infants.

12 Nov 2013

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that it has filed an investigational new drug application with the US Food and Drug Administration to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease.

12 Nov 2013

New study stresses importance of studying freezing episodes in Parkinson's patients

A recent study, led by Ryan P. Duncan of Washington University at St. Louis, suggested patients with Parkinson's disease who suffer from freezing episodes are more likely to have impaired balance than those who do not. This is an important discovery as Parkinson's disease typically develops in elderly patients, who cannot afford to be unstable, lose balance and potentially fall, which could result in major injuries.

12 Nov 2013

European Medicines Agency awards orphan drug designation to NanoViricides' DengueCide

NanoViricides, Inc. announced today that the European Medicines Agency, has awarded orphan drug designation to DengueCide, the Company's drug candidate for the treatment of dengue and dengue hemorrhagic fever.

11 Nov 2013

GW Pharmaceuticals starts Phase 1b/2a clinical trial for Recurrent Glioblastoma Multiforme

GW Pharmaceuticals plc a biopharmaceutical company focused on discovering, developing and commercializing novel therapeutics from its proprietary cannabinoid product platform, announced today it has commenced a Phase 1b/2a clinical trial for the treatment of Recurrent Glioblastoma Multiforme.

11 Nov 2013

FOXO3 transcription factor may protect against alcohol-induced liver injury

New data suggest that the transcription factor FOXO3 may protect against alcohol-induced liver injury. Researchers determined that alcohol given to mice deficient in FOXO3 caused severe liver injury resembling human alcoholic hepatitis.

11 Nov 2013

Women taking immunosuppressive medications during pregnancy do not put their babies at risk

Women with chronic autoimmune diseases who take immunosuppressive medications during their first trimester of pregnancy are not putting their babies at significantly increased risk of adverse outcomes, according to a Vanderbilt study released online by the journal Arthritis and Rheumatism.

11 Nov 2013

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

An innovative Northwestern Medicine- research program investigating if stem cells may be the key to allowing organ transplant patients to stop taking immunosuppressive drugs has received $12 million in research funding. The grant will allow researchers to finish Phase II of the clinical trials and begin Phase III.

8 Nov 2013

Antibe Founder and Chief Science Officer honored with Heymans Foundation Memorial Medal

Antibe Therapeutics Inc. is proud to announce that Dr. John Wallace, the Corporation's Founder and Chief Science Officer, was awarded the Heymans Foundation Memorial Medal in Ghent, Belgium, today.

8 Nov 2013

Findings raise prospects for new therapies to protect heart from progressive disease

Some of the most commonly prescribed drugs for the treatment of heart failure are beta-blockers and nitrates, which help to relax blood vessels and decrease the heart's workload. The drugs were thought to produce those effects through distinct molecular pathways, but according to a new study led by scientists at Temple University School of Medicine, both types of drugs may help the failing heart by counteracting the effects of an enzyme known as GRK2.

8 Nov 2013

Landmark clinical trial of artificial aortic heart valve shows positive results

Loyola University Medical Center is the only Chicago hospital participating in a landmark clinical trial of an artificial aortic heart valve that does not require open heart surgery.

From Medtronic 8 Nov 2013

ImmunGene secures $9 million in Series A financing from Ally Bridge Group

ImmunGene, Inc., a biotechnology company focused on developing antibody-cytokine fusion technology therapies to treat cancer, today announced it has secured $9 million in a milestone-based Series A financing from Ally Bridge Group. Previous investments in the Company were converted into Series A preferred stock. ImmunGene will use the capital to advance its early-stage development products to IND-enabling studies.

7 Nov 2013

Patrys receives FDA Orphan Medicinal Product Designation for PAT-SM6

Patrys Limited, a clinical stage biotechnology company, has received confirmation of Orphan Medicinal Product Designation for its lead anti-cancer product PAT-SM6, from the USA Food and Drugs Administration.

7 Nov 2013

Natura Therapeutics’ natural dietary intervention improves older adults' cognitive functioning

A human clinical study of older adults has demonstrated that participants who took NutraStem Cardio-, a natural dietary supplement created by Natura Therapeutics, Inc., showed a significant increase in cognition when compared to age-matched individuals taking a placebo.

7 Nov 2013

PDL BioPharma closes financing transaction with Durata Therapeutics

PDL BioPharma, Inc. announced today that it closed a financing transaction with Durata Therapeutics, Inc., a pharmaceutical company focused on the development and commercialization of novel therapeutics for patients with infectious diseases and acute illnesses.

6 Nov 2013

New drug combination therapy effectively kills cancer cells

Results from a recent preclinical study have shown that a new drug combination therapy being developed at Virginia Commonwealth University Massey Cancer Center effectively killed colon, liver, lung, kidney, breast and brain cancer cells while having little effect on noncancerous cells. The results lay the foundation for researchers to plan a future phase 1 clinical trial to test the safety of the therapy in a small group of patients.

6 Nov 2013

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

ADC Therapeutics Sarl, a portfolio company of Auven Therapeutics and the oncology drug development company specializing in proprietary antibody drug conjugates, and Five Prime Therapeutics, Inc., a clinical-stage biotechnology company focused on discovering and developing novel protein therapeutics for cancer and inflammatory diseases, today announced an exclusive license agreement for human antibodies directed to an undisclosed target expressed on the surface of various types of cancers.

6 Nov 2013

Therapeutics News and Research

Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

International research consortium to focus on pediatric translational research

Orexigen Therapeutics reports net loss of $18.6 million in Q3 2013

BioGaia plans to invest in first phase of project aimed at developing drug for NEC

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

New study stresses importance of studying freezing episodes in Parkinson's patients

European Medicines Agency awards orphan drug designation to NanoViricides' DengueCide

GW Pharmaceuticals starts Phase 1b/2a clinical trial for Recurrent Glioblastoma Multiforme

FOXO3 transcription factor may protect against alcohol-induced liver injury

Women taking immunosuppressive medications during pregnancy do not put their babies at risk

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

Antibe Founder and Chief Science Officer honored with Heymans Foundation Memorial Medal

Findings raise prospects for new therapies to protect heart from progressive disease

Landmark clinical trial of artificial aortic heart valve shows positive results

ImmunGene secures $9 million in Series A financing from Ally Bridge Group

Patrys receives FDA Orphan Medicinal Product Designation for PAT-SM6

Natura Therapeutics’ natural dietary intervention improves older adults' cognitive functioning

PDL BioPharma closes financing transaction with Durata Therapeutics

New drug combination therapy effectively kills cancer cells

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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