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Machine-learning methods show that patients with severe brain injury could communicate accurately

Only by employing complex machine-learning techniques to decipher repeated advanced brain scans were researchers at NewYork-Presbyterian/Weill Cornell able to provide evidence that a patient with a severe brain injury could, in her way, communicate accurately.

14 Feb 2012

Two studies demonstrate preliminary success of CyBorD in AL amyloidosis

Two studies published today in Blood, the Journal of the American Society of Hematology (ASH), demonstrate preliminary success of an effective multiple myeloma (MM) regimen in patients with AL amyloidosis, a rare and devastating blood disease that results in deposition of damaging abnormal protein in critical organs of the body, including the kidneys, heart, liver, and intestines, and shares some characteristics with MM.

14 Feb 2012

$Physical exercise in early 20's aids bone growth, reduces risk of fractures$

Physical exercise in early 20's aids bone growth, reduces risk of fractures

Physical exercise in the early twenties improves bone development and may reduce the risk of fractures later in life, reveals a study of more than 800 Swedish men carried out at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

14 Feb 2012

CyBorD regimen shows promise against AL amyloidosis

A Mayo Clinic-led study, published in the American Society of Hematology (ASH) journal Blood found that CyBorD, a triple chemotherapy drug combination that has been successful in helping patients with the blood cancer multiple myeloma, also showed promise in improving the care for patients with the rare blood disease AL amyloidosis.

14 Feb 2012

Scientists identify more than 100 new cases of alkaptonuria

Scientists at the University of Liverpool, working with international partners, have shown a rare genetic disease, that causes crippling osteoarthritis in the spine and major joints, is far more prevalent worldwide than previously thought.

14 Feb 2012

Researchers complete systematic review of three major orthopaedic journals

In a new study presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), researchers completed a systematic review of three major orthopaedic journals - the Journal of Bone and Joint Surgery (American and British editions) and the Journal of Arthroplasty (JOA) - for all articles related to metal-on-metal total hip replacement between October 1999 and May 2011.

13 Feb 2012

RUMC sponsors Nutritional Medicine workshop

Rush University Medical Center is sponsoring a Nutritional Medicine workshop March 15 to 16, 2012, that features internationally-renowned faculty who are leaders in research in nutritional medicine.

13 Feb 2012

New method can create scaffolds for tissue engineering applications

Researchers at Northwestern University have developed a new method for creating scaffolds for tissue engineering applications, providing an alternative that is more flexible and less time-intensive than current technology.

13 Feb 2012

TKR surgeries have more than doubled over the past decade

New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found that more than 4.5 million Americans are living with a total knee replacement (TKR), as the number of TKR surgeries has more than doubled over the past decade, with the sharpest rise among younger patients. Osteoarthritis continues to be the primary reason for TKR.

10 Feb 2012

Shorter stay protocols for TKR patients may increase risk of mortality, readmission

No previous research has quantified and compared the costs and outcomes between total knee replacement (TKR) patients who have differing lengths of hospital stay following surgery.

10 Feb 2012

$Hip fracture patients should be screened for cervical myelopathy$

Hip fracture patients should be screened for cervical myelopathy

Hip fractures are a common cause of morbidity and mortality in elderly patients. Cervical myelopathy is a common neurological condition that can diminish balance and coordination. In new research presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), investigators screened 28 hip fracture patients and 35 hip replacement patients for cervical myelopathy. Eighteen percent (five) of the hip fracture patients did indeed have cervical myelopathy. None of the hip replacement patients tested positive for the condition.

10 Feb 2012

Eighth grader develops AnimalGrams to support pediatric cancer research at UCLA

When he was 11, Cameron Cohen created the hit drawing app iSketch for the iPhone and donated $20,000 of the proceeds from its sales to the Chase Child Life program at Mattel Children's Hospital UCLA.

10 Feb 2012

Study shows high cost of defensive orthopaedic care

In a first-ever national survey of orthopaedic surgeons, 96 percent said they have practiced defensive medicine - the ordering of tests, referrals to specialists and hospital admissions primarily to avoid liability and without significant benefit to patients - according to a new study presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons.

10 Feb 2012

Ultrasound reliable alternative to X-rays for DDH screening in children

Developmental dislocation (dysplasia) of the hip (DDH) is a common congenital condition in which a child's upper thighbone is dislocated from the hip socket. The condition can be present at birth or develop during a child's first year of life. Plain radiography (X-rays) has long been the gold standard screening modality for this condition in 6-month-old children, despite concerns over exposing very young children to ionizing radiation.

10 Feb 2012

FDA panel votes against Amgen’s Xgeva in prostate cancer

An FDA panel of oncologists has voted against a new use for Amgen's Xgeva in prostate cancer on Wednesday, saying the drug's ability to slow the spread of the disease did not translate into meaningful benefits for patients. Xgeva is already approved to prevent fractures in cancerous bones, and for osteoporosis, in a different formulation called Prolia.

9 Feb 2012

Web-based follow-up after TJR may improve physician access for critical care

Patients who have had total joint replacement (TJR) are expected to return to their physician's office or clinic regularly for routine follow-up care. In a new study presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), researchers asked 210 TKR patients to either complete a Web-based follow-up, which included an online survey and an X-ray taken at the nearest Internet-enabled facility; or, to return to the clinic/office for their regular appointment.

9 Feb 2012

Antidepressants make patients feel less satisfied after THR

Patients taking antidepressants up to three years prior to undergoing a total hip replacement (THR) were more likely to report greater pain before and after surgery and less satisfaction with their procedure, according to new research presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

9 Feb 2012

British Editorial Society of Bone & Joint Surgery launches new online resource

The British Editorial Society of Bone & Joint Surgery, publishers of The Journal of Bone & Joint Surgery (British Volume) announce the launch of Bone & Joint - a major new online resource for the orthopaedic and related communities.

9 Feb 2012

$Bisphosphonates may raise risk of atypical femur fracture$

Bisphosphonates may raise risk of atypical femur fracture

There is growing evidence that supports an association between atypical fractures of the femur- a rare break of the thigh bone, typically without trauma - and the use of bisphosphonates, drugs proven to enhance bone density and reduce fracture incidence caused by osteoporosis.

9 Feb 2012

Patients should limit sporting activities to maintain hip prosthesis

In hip resurfacing the femoral ball in the hip joint is not removed, but instead is trimmed and capped with a smooth metal covering. Young and active patients with arthritis often choose hip resurfacing over total hip replacement to minimize the risk of hip dislocation, and to preserve the bone for a revision surgery should the primary resurfacing fail. However, the long-term effects of sports on a resurfaced hip were unknown.

9 Feb 2012