Infectious Diseases News and Research

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Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

Cases of new coronavirus rises to 17, number of deaths is 11

"The deadly and mysterious coronavirus that first appeared in Saudi Arabia last year has claimed two more victims, bringing the official death toll to 11," and the case count to 17, the Los Angeles Times' "Booster Shots" blog reports.

28 Mar 2013

CureVac begins CV9104 Phase 2b clinical trial in patients with castration-resistant prostate cancer

CureVac GmbH, a clinical stage biopharmaceutical company that has pioneered the development of a new class of therapies and vaccines based on messenger RNA, today announced that it has initiated a double-blind, randomized Phase 2b clinical trial of its RNActive cancer vaccine, CV9104, for the treatment of patients with castration-resistant prostate cancer.

28 Mar 2013

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

Merck, known as MSD outside the United States and Canada, today announced that the Biologics License Application for its investigational Timothy grass pollen (Phleum pratense) allergy immunotherapy tablet has been accepted for review by the U.S. Food and Drug Administration.

28 Mar 2013

Researcher discovers genetic variations that are linked to breast cancer

Working with an international consortium conducting research on breast, ovarian and prostate cancer among 200,000 people, Professor Jacques Simard, holder of the Canada Research Chair in Oncogenetics at Laval University, was actively involved in the discovery of DNA "spelling mistakes" linked to breast cancer.

28 Mar 2013

Patients taking antihistamines to suppress stomach acid are at greater risk of C. diff infection

Patients receiving antihistamines to suppress stomach acid are at greater risk of infection from Clostridium difficile, or C. diff, a common cause of diarrhea, particularly in health care settings, Mayo Clinic researchers have found.

28 Mar 2013

Researchers examine performance of Africa's expanded programme on immunization

In a paper published in PLoS Medicine last week, researchers from the Vaccines for Africa Initiative at the University of Cape Town's Institute of Infectious Disease and Molecular Medicine examine the performance of the Expanded Programme on Immunization (EPI) in Africa since its inception in 1974.

27 Mar 2013

Microbiologists identify unique resistance mechanisms of E. coli to carbapenems

As public health authorities across the globe grapple with the growing problem of antibiotic resistance, Tufts University School of Medicine microbiologists and colleagues have identified the unique resistance mechanisms of a clinical isolate of E. coli resistant to carbapenems.

27 Mar 2013

FDA clears Soligenix's IND application for SGX942 for treatment of oral mucositis

Soligenix, Inc., a clinical stage biopharmaceutical company, announced today that the Food and Drug Administration has completed its review and cleared the Investigational New Drug application for SGX942 for the treatment of oral mucositis resulting from radiation and/or chemotherapy treatment in head and neck cancer patients.

27 Mar 2013

Lancet series examines tuberculosis

"To commemorate World TB Day 2013, the Lancet Infectious Diseases publishes a series of papers on tuberculosis, a disease that has long plagued human beings and was declared a global emergency in 1993 by WHO," the series homepage states.

27 Mar 2013

EMA accepts Shionogi's ospemifene MAA for treatment of VVA in post-menopausal women

Shionogi Limited, the London-based European subsidiary of Shionogi & Co., Ltd announced today that on 26th March 2013 the European Medicines Agency accepted its Marketing Authorisation Application submission for ospemifene for the treatment of vulvar and vaginal atrophy in post-menopausal women.

27 Mar 2013

Trovagene introduces urine-based HPV-HR DNA test for identifying high-risk HPV strains

Trovagene, Inc., today announced the commercial availability of its urine-based HPV-HR (high-risk) assay, a molecular human papillomavirus test.

27 Mar 2013

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

A research paper published online this month in Academic Medicine highlights the successful development, implementation, and effects of an infectious disease curriculum that has now been piloted in five Boston Public Schools.

27 Mar 2013

Focused approach needed to end TB

Addressing the question of whether the international community can eliminate tuberculosis, Arundhati Maitra and Sanjib Bhakta of the Department of Biological Sciences at the University of London write in an opinion piece in the AlertNet News Blog, "With an estimated 8.7 million reported cases and 1.4 million deaths due to TB in 2011, the question above poses one of the most serious challenges faced by the scientific community, health care industry, government and public organizations worldwide."

26 Mar 2013

Challenges remain in fight against TB, U.N. Secretary-General says

On World Tuberculosis Day, recognized on March 24, U.N. Secretary-General Ban Ki-moon "said that while there has been much progress since the World Health Organization declared TB a global health emergency two decades ago, there are still challenges to be met, mainly stopping the spread of multidrug-resistant TB, also known as MDR-TB, which threatens to reverse the gains achieved in past years," the U.N. News Centre reports.

26 Mar 2013

Blogs address issues surrounding TB, World TB Day

On Sunday, March 24, the international community observed World TB Day. The following is a summary of blog posts published in recognition of the day.

26 Mar 2013

A new strategy to prevent herpes virus infections

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1).

26 Mar 2013

Researchers test protease inhibitors with potential for prevention, treatment of norovirus infection

A Kansas State University-led team is researching ways to stop the spread of norovirus, a contagious stomach illness that infects one in 15 Americans each year, according to the Centers for Disease Control and Prevention.

25 Mar 2013

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Collaborating scientists from Nationwide Children's Hospital, Baylor Institute for Immunology Research, and Mount Sinai School of Medicine have identified an important mechanism for stimulating protective immune responses following seasonal influenza vaccinations.

25 Mar 2013

Researchers identify a new approach for treating brain metastases associated with lung cancer

Lung cancer is the world's most common cause of death from cancer. In Austria, around 4,000 people develop this type of cancer every year. One particular problem is the development of brain metastases in association with the lung tumour.

24 Mar 2013

Infectious Diseases News and Research

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Cases of new coronavirus rises to 17, number of deaths is 11

CureVac begins CV9104 Phase 2b clinical trial in patients with castration-resistant prostate cancer

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

Researcher discovers genetic variations that are linked to breast cancer

Patients taking antihistamines to suppress stomach acid are at greater risk of C. diff infection

Researchers examine performance of Africa's expanded programme on immunization

Microbiologists identify unique resistance mechanisms of E. coli to carbapenems

FDA clears Soligenix's IND application for SGX942 for treatment of oral mucositis

Lancet series examines tuberculosis

EMA accepts Shionogi's ospemifene MAA for treatment of VVA in post-menopausal women

Trovagene introduces urine-based HPV-HR DNA test for identifying high-risk HPV strains

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

Focused approach needed to end TB

Challenges remain in fight against TB, U.N. Secretary-General says

Blogs address issues surrounding TB, World TB Day

A new strategy to prevent herpes virus infections

Researchers test protease inhibitors with potential for prevention, treatment of norovirus infection

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Researchers identify a new approach for treating brain metastases associated with lung cancer

Industry Focus eBook - Infectious Diseases (3rd Edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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