Efficacy News and Research

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Clinical Research Pathways, WellStar Health System partner to increase diversity in oncology research

Clinical Research Pathways is partnering with WellStar Health System to increase diversity in oncology research to help ensure that new cancer medicines are effective for patients of all races and ethnicities.

12 Dec 2019

Help for teenagers who want to quit smoking

A new study published in the journal JAMA Pediatricsreports on the use of varenicline, a drug that helps smokers quit. The study is unique in that it targeted teenagers who wanted to quit. While confirming the low overall efficacy of the drug, it shows that it may perhaps help teenage smokers to quit faster and to stay smoke-free longer.

11 Dec 2019

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.

11 Dec 2019

Evaluating safety and efficacy of migraine preventive treatment for children, adolescents

Cephalalgia, the official journal of the International Headache Society, published the article entitled "Cinnarizine and sodium valproate as the preventive agents of pediatric migraine: A randomized double-blind placebo-controlled trial", by Man Amanat, and Mahmoud Reza Ashrafi from the Tehran University of Medical Sciences, Tehran, Iran.

10 Dec 2019

Study focuses on smoking cessation treatment for adolescents

Preventable deaths are those that can be stymied by public health intervention, and deaths related to tobacco use are at the top of that list in the United States as well as globally.

10 Dec 2019

Older people today may not be any lonelier than their counterparts from prior generations

Despite some claims that Americans are in the midst of a "loneliness epidemic," older people today may not be any lonelier than their counterparts from previous generations - there just might be more of them, according to a pair of studies published by the American Psychological Association.

10 Dec 2019

New strategies needed to manage ibrutinib-related toxicities in CLL patients, study suggests

New findings by Yale Cancer Center and Smilow Cancer Hospital researchers show that as the use of the drug ibrutinib climbs in patients with chronic lymphocytic leukemia, so do the rates of patients who stop taking the drug.

9 Dec 2019

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy.

9 Dec 2019

New nanoparticle innovation detects vascular calcification in atherosclerosis

Heart disease and stroke are the world's two most deadly diseases, causing over 15 million deaths in 2016 according to the World Health Organization.

9 Dec 2019

Trial investigating "abortion pill reversal" stops due to safety concerns

Scientists are calling for pro-life US states to abolish an unproven medication that supposedly "reverses" medical abortion.

9 Dec 2019

Ibrutinib-based therapy provides superior clinical outcomes in majority of CLL patients

The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) today announced results from an extended follow-up analysis of patients in its randomized Phase 3 clinical trial, E1912.

8 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

Pilot clinical trial tests new treatment for type 1 diabetes

Type 1 diabetes is a chronic condition in which the body's own immune system attacks and destroys beta cells in the pancreas. Once the beta cells are destroyed, the pancreas can no longer produce insulin. Currently, there is no cure for T1D and treatment focuses on managing blood sugar levels.

6 Dec 2019

Breakthrough research develops novel vaccine poised to cure peanut allergies

Peanut allergies could become a thing of the past as breakthrough research from the University of South Australia develops a radically novel vaccination that's poised to cure the potentially life threatening condition.

6 Dec 2019

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

US pharmaceutical industry continues to shine according to CPhI 2019 Annual Report

The US pharmaceutical industry continues to lead its global peers in terms of innovation and competitiveness, while still ranking high in overall growth potential despite its mature status, according to the results of a survey of 350 global pharmaceutical industry executives published as part of the recently released CPhI 2019 Annual Report.

From LabVantage Solutions 6 Dec 2019

Typhoid conjugate vaccine proves its worth in the field

A new typhoid conjugate vaccine (TCV) that has been approved by the World Health Organization (WHO) Global Advisory Committee on Vaccine Safety has proved extremely effective in both young children and adults in a high-endemicity area for the first time. With almost 82% of recipients showing protection against typhoid, the vaccine promises to help control this deadly disease that claims up to 160,000 of its 11 million victims each year.

5 Dec 2019

Deep age predictors can help advance aging research

The deep age predictors can help advance aging research by establishing causal relationships in nonlinear systems.

5 Dec 2019

More evidence of effectiveness required to sustain simulation education, say experts

Simulation education has evolved significantly over the years and has become essential to preparing nurses for clinical practice, but sustaining its evolution will require greater evidence of its effectiveness.

4 Dec 2019

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

LUNAC Therapeutics, a UK based drug discovery company focused on the identification and development of advanced anticoagulants with minimal bleeding risk, today announced that, along with the Medicines Discovery Catapult and the University of Leeds, it has been awarded £3.14M funding under Innovate UK’s Biomedical Catalyst program.

4 Dec 2019

Efficacy News and Research

Clinical Research Pathways, WellStar Health System partner to increase diversity in oncology research

Help for teenagers who want to quit smoking

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Evaluating safety and efficacy of migraine preventive treatment for children, adolescents

Study focuses on smoking cessation treatment for adolescents

Older people today may not be any lonelier than their counterparts from prior generations

New strategies needed to manage ibrutinib-related toxicities in CLL patients, study suggests

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

New nanoparticle innovation detects vascular calcification in atherosclerosis

Trial investigating "abortion pill reversal" stops due to safety concerns

Ibrutinib-based therapy provides superior clinical outcomes in majority of CLL patients

New startup aims to prevent reperfusion-related organ damage after liver transplant

Pilot clinical trial tests new treatment for type 1 diabetes

Breakthrough research develops novel vaccine poised to cure peanut allergies

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

US pharmaceutical industry continues to shine according to CPhI 2019 Annual Report

Typhoid conjugate vaccine proves its worth in the field

Deep age predictors can help advance aging research

More evidence of effectiveness required to sustain simulation education, say experts

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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