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Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Pfizer Inc. presented today the results from a Phase 3 study demonstrating the immunogenicity, tolerability and safety of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine Diphtheria CRM197 Protein)in adults infected with human immunodeficiency virus (HIV).

5 Mar 2013

Exercise during pregnancy can reduce rate of cesarean deliveries in healthy pregnant women

Researchers at the Universidad Politécnica de Madrid have found that regular and supervised exercise by experts during pregnancy can reduce the rate of instrumental and cesarean deliveries in healthy pregnant women.

4 Mar 2013

Researchers discover new candidate disease proteins for neurodegenerative disorders

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders.

4 Mar 2013

PsiOxus completes enrollment in MT-102 Phase II trial on cancer cachexia

PsiOxus Therapeutics, Ltd. (PsiOxus), a development stage biotechnology company, has completed patient enrollment for its Phase II clinical trial to study MT-102, a small molecule therapeutic for the treatment of cancer cachexia.

4 Mar 2013

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Researchers supported by The ALS Association have discovered how mutations in new amyotrophic lateral sclerosis (ALS) genes cause not only ALS but also other diseases of the brain, muscle and bone.

4 Mar 2013

Study identifies two gene mutations that lead to death of nerve cells in ALS

A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

4 Mar 2013

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

Clothing closely linked to peak performance for skiers

The sport of cross-country skiing has always been preoccupied with its skis and waxing. Research now demonstrates that to shave off those extra hundredths of a second, competitive skiers should pay more attention to their clothing.

3 Mar 2013

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain access to oxygen and nutrients, necessitating an expansion of the cardiac vasculature.

2 Mar 2013

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.

2 Mar 2013

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for under-served medical needs in neurology and cardiology, announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).

1 Mar 2013

Thyroid hormone may help reduce heart damage in humans with cardiac diseases

Thyroid hormone treatment administered to rats at the time of a heart attack (myocardial infarction) led to significant reduction in the loss of heart muscle cells and improvement in heart function, according to a study published by a team of researchers led by A. Martin Gerdes and Yue-Feng Chen from New York Institute of Technology College of Osteopathic Medicine.

1 Mar 2013

Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

Otsuka Pharmaceutical Co., Ltd. (Otsuka) and H. Lundbeck A/S (Lundbeck) announced the U.S. Food and Drug Administration (FDA) has approved ABILIFY MAINTENA (aripiprazole) for extended- release injectable suspension, an intramuscular (IM) depot formulation indicated for the treatment of schizophrenia.

1 Mar 2013

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Researchers at the University of Michigan School of Kinesiology have received a $1 million grant to study how exercise and other therapies might work differently in lean and obese individuals.

28 Feb 2013

New findings could help develop treatments for inherited disorders

Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments for inherited muscle, brain, bone and skin disorders.

27 Feb 2013

Abell Foundation to award $50,000 to 3 Johns Hopkins researchers for medical inventions

Johns Hopkins' John Wong, Ph.D., has won a BioMaryland LIFE Award, and Ronald Berger, M.D., Ph.D., and Hien Nguyen, M.D., were awarded funds from the Abell Foundation, the researchers learned last week. Each of the winners will receive $50,000 to help develop their discoveries for clinical use.

27 Feb 2013

Muscle News and Research

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Exercise during pregnancy can reduce rate of cesarean deliveries in healthy pregnant women

Researchers discover new candidate disease proteins for neurodegenerative disorders

PsiOxus completes enrollment in MT-102 Phase II trial on cancer cachexia

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Study identifies two gene mutations that lead to death of nerve cells in ALS

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

Clothing closely linked to peak performance for skiers

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Thyroid hormone may help reduce heart damage in humans with cardiac diseases

Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

U-M to study how exercise, other therapies might work differently in lean and obese individuals

New findings could help develop treatments for inherited disorders

Abell Foundation to award $50,000 to 3 Johns Hopkins researchers for medical inventions

Shionogi receives FDA approval for Osphena to treat women with severe dyspareunia

Breakthrough study aims at developing first comprehensive model of fetal heart

COPD benzodiazepine warning

With sequester day looming, partisan differences become more entrenched

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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