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Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

All humans carry genetic variations in their DNA, called Single Nucleotide Polymorphisms (SNPs) that can underlie susceptibility to diseases such as diabetes and cancer.

28 Apr 2022

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

Scientists identify the neural basis of pleasant touch sensation

Studying mice, scientists at Washington University School of Medicine in St. Louis have identified a neural circuit and a neuropeptide - a chemical messenger that carries signals between nerve cells - that transmit the sensation known as pleasant touch from the skin to the brain.

28 Apr 2022

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Massachusetts General Hospital researchers have developed a novel treatment strategy that has the potential to bring the life-saving benefits of chimeric antigen receptor T-cell therapy (CAR T) to patients with acute myeloid leukemia (AML) the most common form of leukemia in adults.

28 Apr 2022

Sleep deprivation negatively affects the stem cells in the cornea

Sleep deprivation, which means getting too little high-quality sleep, is a serious health problem. More than one-third of people in the USA report getting less than the recommended minimum of seven hours sleep per night.

28 Apr 2022

Aspirin for non-obstructive coronary artery disease does not reduce major cardiovascular events

Aspirin therapy, as opposed to statin use, for non-obstructive coronary artery disease does not reduce major cardiovascular events, according to a new study published in the journal Radiology: Cardiothoracic Imaging.

28 Apr 2022

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma.

28 Apr 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

Acute kidney injury among pediatric COVID-19 patients admitted to the ICU in North America

In a recent study published in PLoS ONE, researchers analyzed acute kidney injury (AKI) in coronavirus disease 2019 (COVID-19) pediatric patients.

28 Apr 2022

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

Low dose aspirin is downgraded for preventing cardiovascular disease

A recent article posted in the Journal of the American Medical Association (JAMA) analyzed aspirin use to prevent cardiovascular disease (CVD) and colorectal cancer (CRC).

27 Apr 2022

Novel plug-and-play multi-organ chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context.

27 Apr 2022

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Rhabdomyosarcoma is a type of soft tissue cancer. Scientists at St. Jude Children's Research Hospital studied the population of cells that persists after therapy, causing rhabdomyosarcoma recurrence.

27 Apr 2022

Combination therapy shows promise for treating triple-negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions have identified a combination therapy for treating triple-negative breast cancer (TNBC) that results in durable tumor regression in an animal model of the condition.

27 Apr 2022

New insight into the body’s response to tuberculosis may help design a more effective vaccine

More than 1.7 billion people - or a quarter of the world's population - are infected with Mycobacterium tuberculosis, the bacterial strain that causes tuberculosis (TB).

27 Apr 2022

New findings show rise in racial disparities as availability of proton beam therapy increased in the U.S.

Two new large studies led by researchers at the American Cancer Society (ACS) show an increase in the use of proton beam therapy (PBT) for patients with cancer in the United States during the past decade.

27 Apr 2022

Therapy News and Research

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Artificial circular RNAs found to bypass cellular antiviral responses

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Scientists identify the neural basis of pleasant touch sensation

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Sleep deprivation negatively affects the stem cells in the cornea

Aspirin for non-obstructive coronary artery disease does not reduce major cardiovascular events

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

Acute kidney injury among pediatric COVID-19 patients admitted to the ICU in North America

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

Low dose aspirin is downgraded for preventing cardiovascular disease

Novel plug-and-play multi-organ chip can be customized to the patient

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Combination therapy shows promise for treating triple-negative breast cancer

New insight into the body’s response to tuberculosis may help design a more effective vaccine

New findings show rise in racial disparities as availability of proton beam therapy increased in the U.S.

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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