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Biomarkers responsible for exhaustion in cancer linked to fatigue in Parkinson's disease

Biological markers responsible for extreme exhaustion in patients with cancer have now been linked to fatigue in those with Parkinson's disease, according to new research from Rice University.

10 Aug 2018

Ability to detect RNA helps promote rapid growth, survival of fruit fly larvae

Fruit fly larvae can taste ribonucleosides, the building blocks of gene transcripts, according to a new study publishing on August 7 in the open access journal PLOS Biology by Hubert Amrein and Dushyant Mishra of Texas A&M Health Science Center and their colleagues.

10 Aug 2018

Study of proteins' interaction in brain cells may help develop new therapies for epilepsy

New therapies could be on the horizon for people living with epilepsy or anxiety, thanks to a breakthrough discovery by UNLV, Tufts University School of Medicine, and an international team of researchers studying how proteins interact to control the firing of brain cells.

10 Aug 2018

Scientists identify key neurobiological mechanisms that control aggression

A number of psychiatric disorders present with aggression and violence, which, needless to say, are destructive to both individuals and societies worldwide: death, disease, disability, and numerous socioeconomic problems can often be traced back to aggressive behavior.

9 Aug 2018

Gene considered as tumor promoter may also halt development of cancer, shows study

A gene that has for decades been considered a tumor promoter, the PLK1 gene, can also perform the exact opposite function: halting the development of cancer.

9 Aug 2018

New drug makes rats to self-administer alcohol less frequently

Alcohol use disorders can have devastating effects on a person's health, relationships and finances. Yet for some, the feeling they get when taking a drink temporarily outweighs these other concerns.

9 Aug 2018

Researchers study whether chemotherapy could be encased in milk particles

You can't eat chemotherapy. That's because your digestive system breaks down the molecules you eat into smaller pieces that can be absorbed through the gut into the bloodstream.

9 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

New CAR T-cell immunotherapy trial targets solid tumors

Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 trial, STRIvE-01, cancer-fighting CAR T cells will target the EGFR protein expressed in many childhood sarcoma, kidney and neuroblastoma tumors.

7 Aug 2018

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

A biochemistry instructor curious about an enzyme discovered in the damaged neurons of people with multiple sclerosis made a leap toward a potential cure for countless neurodegenerative ills.

7 Aug 2018

Researchers use PET tracer to identify ER expression differences in metastatic breast cancer patients

In metastatic breast cancer, prognosis and treatment is largely influenced by estrogen receptor expression of the metastases.

7 Aug 2018

Digestive hormone influences pancreatic cancer growth and spread

A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin, a digestive hormone.

3 Aug 2018

New nuclear medicine test could improve care of patients with type 1 diabetes

Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies.

3 Aug 2018

Otsuka’s JINARC approved for treatment of patients with CKD stage 4 ADPKD

Otsuka Pharmaceutical Europe Ltd. today announced that the European Commission has approved an extension of indication for JINARC to include adult patients with CKD stage 4 Autosomal Dominant Polycystic Kidney Disease

2 Aug 2018

Alzheimer's drug may prevent disease progression if used before symptoms appear

About 50 percent of people who reach the age of 85 will develop Alzheimer's disease. Most will die within about five years of exhibiting the hallmark symptoms of the disease - severe memory loss and a precipitous decline in cognitive function.

2 Aug 2018

Protein known to drive nerve cell survival may protect children from Duchenne cardiomyopathy

A protein known to drive nerve cell survival in the brain and spinal cord might also protect failing hearts in children and young adults with Duchenne muscular dystrophy, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions, a premier global exchange of the latest advances in basic cardiovascular science.

2 Aug 2018

Exenatide treatment improves depression symptoms in PD patients

Non-motor symptoms of Parkinson's disease, such as depression, apathy, cognitive impairment, sleep disorders, and sensory symptoms, can have a greater impact on health-related quality of life than motor deficits.

1 Aug 2018

Researchers discover how chronic infections can outsmart the immune system

Like many chronic infections, visceral leishmaniasis thwarts the immune system's defenses so it can settle comfortably into its host.

1 Aug 2018

European Commission approves Pfizer’s first oncology biosimilar

Pfizer Inc. today announced the European Commission has approved TRAZIMERA, a biosimilar to Herceptin (trastuzumab), for the treatment of human epidermal growth factor overexpressing breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

31 Jul 2018

New research into how cells communicate could pave way for improved cancer treatments

Pioneering new research into the way in which cells communicate with each other could hold the key to unlocking new, improved treatment for life-threatening diseases, including cancer.

31 Jul 2018