Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

TSRI scientists discover viable strategy for weight loss in people

Scientists at The Scripps Research Institute have discovered key details of a brain-to-body signaling circuit that enables roundworms to lose weight independently of food intake. The weight-loss circuit is activated by combined signals from the worm versions of the neurotransmitters serotonin and adrenaline, and there are reasons to suspect that it exists in a similar form in humans and other mammals.

11 Oct 2013

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease exhibit mild to moderate depression, which is often underdiagnosed. It is unclear whether depression results from having a debilitating disease or reflects a parallel abnormal change in the brain caused by PD pathophysiology.

11 Oct 2013

Alkermes' ALKS 5461 drug gets FDA Fast Track status for major depressive disorder

Alkermes plc today announced that the U.S. Food and Drug Administration has granted Fast Track status for ALKS 5461 for the adjunctive treatment of major depressive disorder in patients with an inadequate response to standard therapies.

10 Oct 2013

Alkermes announces plans to advance ALKS 5461 phase 3 program for major depressive disorder

Alkermes plc today announced that it has successfully completed its End-of-Phase 2 interactions with the U.S. Food and Drug Administration (FDA), and the company plans to advance ALKS 5461 into phase 3 development in early 2014.

9 Oct 2013

New smartphone app puts genetic information in the hands of people

Until now, understanding and using genetic information has depended on the scientists and doctors who do the testing. No longer.

9 Oct 2013

Brain & Behavior Research Foundation to hold research symposium on mental health

The Brain & Behavior Research Foundation, an organization dedicated to improving the lives of those with mental illness through the transformative power of neuroscience and psychiatric research, will hold its 25th Annual Mental Health Research Symposium on Friday, October 25th from 9:00 am to 4:30 p.m. at the Kaufman Music Center, located at 129 W. 67th St. in New York City.

8 Oct 2013

Study: Effect of medication treatments on patients with alcoholism and anxiety

Domenic Ciraulo, MD, chair of psychiatry at Boston University School of Medicine (BUSM) and David H. Barlow, PhD, professor of psychology at Boston University (BU), have collaborated to study the effect of behavioral and medication treatments on patients with alcoholism and anxiety.

8 Oct 2013

PMDD may shed light on complex interactions between sex hormones and mood

Improved understanding of the role of female sex hormones on the drivers and symptoms of premenstrual dysphoric disorder (PMDD) may shed light on the complex interactions between sex hormones and mood, potentially helping to explain the increased prevalence of mood disorders in women.

8 Oct 2013

Glutamergic agents may be used as novel treatment for mood and anxiety disorders

Glutamergic agents may one day be used as a novel treatment for mood and anxiety disorders, new research presented at the 26th ECNP Congress suggests.

7 Oct 2013

Study: One in three teens with bipolar disorder develop substance abuse

A study published in the October 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that approximately one in three teens with bipolar disorder developed substance abuse, for the first time, during 4 years of follow-up.

3 Oct 2013

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

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1 Oct 2013

FDA approves Brintellix drug to treat depressive disorder in adults

The U.S. Food and Drug Administration today approved Brintellix (vortioxetine) to treat adults with major depressive disorder.

1 Oct 2013

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

A little-used class of antidepressants appears potentially effective in combating a particularly deadly form of lung cancer, according to a new study from researchers at the Stanford University School of Medicine.

27 Sep 2013

Study: Antidepressant drugs prove to be effective against SCLC patients

A bioinformatics approach to repurposing drugs resulted in identification of a class of antidepressants as a potential new treatment for small-cell lung cancer (SCLC), according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

27 Sep 2013

Experiments with neutrons show antidepressant lithium accumulates strongly in white matter of the brain

At present lithium is most popular for its use in rechargeable batteries. But for decades now, lithium has also been used to treat various psychological diseases such as depressions, manias and bipolar disorders. But, the exact biological mode of action in certain brain regions has hardly been understood. It is well known that lithium lightens moods and reduces aggression potential.

27 Sep 2013

Depressed smokers may benefit from mood management interventions

Studies have shown that people with depression are about twice as likely to smoke cigarettes as people without depression and they are less likely to successfully quit than smokers without depression.

20 Sep 2013

Guidance for medication in bipolar depression published

Solid evidence to guide the use of antidepressants in patients with bipolar disorder is “remarkably limited,” says the International Society for Bipolar Disorders Task Force.

18 Sep 2013

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Results of a Pfizer-commissioned study published this month in Annals of Internal Medicine reveal that smokers with a past or present diagnosis of major depressive disorder (MDD)* taking varenicline had a significantly higher likelihood of quitting smoking (after 12 weeks and at 52 weeks) than those who were given a placebo.

18 Sep 2013

Emotional stress, cognitive impairment linked to early hospital readmission of heart patients

Heart patients' mental state and thinking abilities may help predict whether costly and potentially dangerous early hospital readmission will follow their release after treatment, according to the results of a significant new study by Henry Ford Hospital researchers.

18 Sep 2013

New behavioral therapy improves antidepressant treatment of OCD

NIMH grantees have demonstrated that a form of behavioral therapy can augment antidepressant treatment of obsessive compulsive disorder (OCD) better than an antipsychotic.

13 Sep 2013

Antidepressant News and Research

Further Reading

TSRI scientists discover viable strategy for weight loss in people

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

Alkermes' ALKS 5461 drug gets FDA Fast Track status for major depressive disorder

Alkermes announces plans to advance ALKS 5461 phase 3 program for major depressive disorder

New smartphone app puts genetic information in the hands of people

Brain & Behavior Research Foundation to hold research symposium on mental health

Study: Effect of medication treatments on patients with alcoholism and anxiety

PMDD may shed light on complex interactions between sex hormones and mood

Glutamergic agents may be used as novel treatment for mood and anxiety disorders

Study: One in three teens with bipolar disorder develop substance abuse

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

FDA approves Brintellix drug to treat depressive disorder in adults

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

Study: Antidepressant drugs prove to be effective against SCLC patients

Experiments with neutrons show antidepressant lithium accumulates strongly in white matter of the brain

Depressed smokers may benefit from mood management interventions

Guidance for medication in bipolar depression published

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Emotional stress, cognitive impairment linked to early hospital readmission of heart patients

New behavioral therapy improves antidepressant treatment of OCD

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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