Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Could drinking tea help manage COVID-19?

Researchers summarized the content of active ingredients in different types of tea, the second most consumed beverage in the world. They also explored the possibility of using tea extracts for coronavirus disease 2019 (COVID-19) prevention and treatment.

17 Jan 2023

Understanding the molecular basis of how THC cannabinoid inhibits an important human enzyme

In various European countries and North America, medical cannabis or medicines based on cannabinoids are authorized for therapeutic purposes.

9 Jan 2023

CU researchers discover a new mechanism for slowing cardiac fibrosis

Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue - a process known as cardiac fibrosis.

6 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Insilico Medicine, a clinical stage, end-to-end artificial intelligence (AI)-driven drug discovery company, held the launch ceremony for Life Star – a 6th generation Intelligent Robotics Drug Discovery Laboratory – in Suzhou BioBAY Industrial Park on Dec. 29.

5 Jan 2023

Early intervention key to managing diabetes, cardiorenal, and metabolic diseases

A panel of US-based experts in cardiology, nephrology, endocrinology, and primary care has prepared specific recommendations for early identification and intervention in obesity, diabetes, and other cardiorenal and metabolic diseases. A detailed report on recommended strategies has been published in the Journal of Diabetes and its Complications.

4 Jan 2023

Researchers discover novel candidate drug targets for advanced non-alcoholic fatty liver disease

Using the latest technologies - including both single-nuclear sequencing of mice and human liver tissue and advanced 3D glass imaging of mice to characterize key scar-producing liver cells - researchers have uncovered novel candidate drug targets for non-alcoholic fatty liver disease (NAFLD).

4 Jan 2023

Synthetic tissue repairs injuries and restores normal erectile function in pig model

Scientists have developed a synthetic tissue that repairs injuries and restores normal erectile function in a pig model, in a study publishing January 4 in the journal Matter.

4 Jan 2023

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

Researchers conducted a literature review to determine whether platelet-rich plasma therapy could help slow disease progression through lung regeneration in patients with chronic respiratory disease.

4 Jan 2023

The metabolic links between diet-induced changes in the gut and NASH

Scientists reviewed the metabolic association between diet-induced alterations in the gut and NASH

4 Jan 2023

Study reveals novel role of PPARγ acetylation in macrophages in impairing adipose tissue function

As a chronic pro-inflammatory disease, obesity is closely associated with the development of various diseases such as type 2 diabetes, cardiovascular disease and cancers. Obesity is now a major concern for public health.

30 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Cystic fibrosis drug shows promise to treat pneumonia

Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome.

22 Dec 2022

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Researchers examined the pathological impacts of the structural components of SARS-CoV-2 on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health.

20 Dec 2022

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York have discovered that common cancer treatments, such as radiotherapy or anthracycline drugs, cause long-term damage to heart tissue by activating a key inflammatory signaling pathway.

19 Dec 2022

Changing heart cell programming can reverse the lasting damage caused by heart attacks

Back in 1971, the Bee Gees asked, "How can you mend a broken heart?". Now, researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure.

16 Dec 2022

No benefit of low dose apixaban following acute COVID-19

The HEAL-COVID trial compared the efficacy of Apixaban to standard care in adults who have recently recovered from severe COVID-19.

14 Dec 2022

The therapeutic effects and safety of psychedelics

Psychedelics are reported to have rapid-onset and long-lasting therapeutic benefits after a single or few doses.

14 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Fibrosis News and Research

Further Reading

Could drinking tea help manage COVID-19?

Understanding the molecular basis of how THC cannabinoid inhibits an important human enzyme

CU researchers discover a new mechanism for slowing cardiac fibrosis

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Early intervention key to managing diabetes, cardiorenal, and metabolic diseases

Researchers discover novel candidate drug targets for advanced non-alcoholic fatty liver disease

Synthetic tissue repairs injuries and restores normal erectile function in pig model

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

The metabolic links between diet-induced changes in the gut and NASH

Study reveals novel role of PPARγ acetylation in macrophages in impairing adipose tissue function

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Cystic fibrosis drug shows promise to treat pneumonia

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Changing heart cell programming can reverse the lasting damage caused by heart attacks

No benefit of low dose apixaban following acute COVID-19

The therapeutic effects and safety of psychedelics

How human cell atlases provide the missing links between genes, diseases and therapies

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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