Fluorescence News and Research

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SARS-CoV-2 can be neutralized by UV-A and UV-B

Since the end of the 1800s, Ultra-violet (UV) light has been widely documented for its germicidal properties. The UV-C light produced by low-pressure mercury tubes is widely used for disinfecting wastewater, closed environments, and biological products and is well-established, safe, and economical. UV light can have a germicidal effect on bacteria and viruses.

2 Jun 2021

Study shows how scar tissue cells in the injured heart can be converted to heart muscle cells

It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a new study, researchers from the University of Tsukuba have shown how cells in the scar tissue can be converted to heart muscle cells, effectively regenerating the injured heart.

2 Jun 2021

AMSBIO's custom lentivectors for labeling organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

A novel multiplexed diagnostic approach for COVID-19

Researchers developed a platform for detecting the virus directly from a patient's sample as well as the immune response through antibodies such as IgG and IgM.

31 May 2021

Study shows that breast cancer can be prevented with better contraception choices

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

29 May 2021

New light-sheet fluorescence microscope provides high spatial resolution, lowers phototoxicity

A research group led by Takashi Saito, of the Ehime University Graduate School of Medicine, developed a 2-photon excitation light-sheet fluorescence microscope which (1) lowers phototoxicity, (2) extends the field of view, and (3) heightens spatial resolution.

29 May 2021

New tool will help identify the most promising protein molecules for drug development

A cutting-edge digital tool that will make it cheaper, safer and faster for pharmaceutical companies to predict protein stability - a vital step in the development of new medicines - is being rolled out by scientists from the UK's University of Bath through their spin-out company, BLOC Labs.

28 May 2021

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body.

28 May 2021

Researchers use new technique to visualize brain tissue noninvasively

The way the human brain works remains, to a great extent, a topic of controversy. One reason is our limited ability to study neuronal processes at the level of single cells and capillaries across the entire living brain without employing highly invasive surgical methods. This limitation is now on the brink of change.

28 May 2021

Beckman Coulter Life Sciences launches next-generation Biolector XT Microbioreactor

Microbioreactor technology is accelerating and increasing automation capabilities with the launch of the new BioLector XT Microbioreactor which features the highest flexibility, enabling more applications in the BioLector series of instruments from m2p-labs, part of the Beckman Coulter Life Sciences’ Biotechnology Business Unit since November 2020.

From Beckman Coulter Life Sciences - Flow Cytometry 27 May 2021

New plasmofluidic chip could speed up diagnosis during current and future pandemics

Reverse transcription-polymerase chain reaction (RT-PCR) has been the gold standard for diagnosis during the COVID-19 pandemic.

27 May 2021

CASdetec: new CRISPR-based SARS-CoV-2 detection platform detects nucleic acids with high sensitivity and specificity

To add to existing CRISPR-based nucleic acid detection protocols, a team of researchers recently established a new SARS-CoV-2 detection protocol based on their previously reported platform - CDetection (Cas12b-mediated DNA detection). They combined nucleic-acid amplification methods and sample treatment protocols with CDetection and established an integrated nucleic acid detection platform called CRISPR-assisted detection or CASdetec. CASdetec has a detection limit of 1×104 copies/mL for SARS-CoV-2 pseudovirus, without any observed cross-reactivity.

26 May 2021

Superoxide produced in the inner ear cochlea causes major types of acquired hearing loss

Professor UEYAMA Takehiko (Biosignal Research Center, Kobe University) and the inner ear research group (Kyoto Prefectural University of Medicine) have identified the cell types in the inner ear cochlea responsible for the production of superoxide (Nox3-expressing cells).

25 May 2021

SARS-CoV-2 B.1.1.7 and B.1.351 variants exhibit enhanced affinity towards the ACE2 receptor

In a short correspondence paper recently uploaded to the Lancet by Ramanathan, Muthukumar et al. (May 19th, 2021) the affinity of labeled SARS-CoV-2 spike receptor-binding domain proteins sourced from each of these two variants of concern towards human angiotensin-converting enzyme 2 (ACE2) recombinant proteins is investigated using microscale thermophoresis, confirming the enhanced affinity towards the receptor observed in other studies.

22 May 2021

Oxytocin-vasopressin circuit has distinct dynamics throughout embryonic development

The work, carried out by Pilar Madrigal and Sandra Jurado, from the UMH-CSIC Neurosciences Institute in Alicante, a joint center of the Spanish National Research Council and Miguel Hernández University, has been published in Communications Biology, a Nature group´s journal.

22 May 2021

New study will help investigate innate immune responses to viral infections

Researchers from Boston University School of Medicine (BUSM) report the formation of human cells containing a green fluorescent protein or GFP (one of the most important proteins in biology and fluorescence imaging) genetically fused with two interferon stimulated genes (ISGs), namely Viperin and ISG15.

19 May 2021

Fluorescence News and Research

SARS-CoV-2 can be neutralized by UV-A and UV-B

Study shows how scar tissue cells in the injured heart can be converted to heart muscle cells

AMSBIO's custom lentivectors for labeling organoids

A novel multiplexed diagnostic approach for COVID-19

Study shows that breast cancer can be prevented with better contraception choices

New light-sheet fluorescence microscope provides high spatial resolution, lowers phototoxicity

New tool will help identify the most promising protein molecules for drug development

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Researchers use new technique to visualize brain tissue noninvasively

Beckman Coulter Life Sciences launches next-generation Biolector XT Microbioreactor

New plasmofluidic chip could speed up diagnosis during current and future pandemics

CASdetec: new CRISPR-based SARS-CoV-2 detection platform detects nucleic acids with high sensitivity and specificity

Superoxide produced in the inner ear cochlea causes major types of acquired hearing loss

SARS-CoV-2 B.1.1.7 and B.1.351 variants exhibit enhanced affinity towards the ACE2 receptor

Oxytocin-vasopressin circuit has distinct dynamics throughout embryonic development

New study will help investigate innate immune responses to viral infections

New coronavirus test can get fast, accurate results from saliva samples

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

Novel approach to immunotherapy design could pave the way for new brain cancer treatments

New glowing probe may detect early cardiovascular disease

Choosing the right benchtop fluorescence microscope: A practical buyer's guide eBook

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