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Understanding the immune responses after secondary vaccinations with Pfizer and Moderna vaccines

In a new study, researchers assessed the serological responses to secondary booster doses of Pfizer's Comirnaty and Moderna's Spikevax COVID-19 vaccines.

23 Feb 2022

Study shows Pfizer-BioNTech booster protects over 65s against Delta and Omicron

New research in nursing home residents found that a third dose of the Pfizer-BioNTech COVID-19 vaccine was effective for at least three months in protecting against the Delta and Omicron variant. While two doses of an mRNA COVID-19 vaccine showed poor neutralization to Omicron than Delta, a booster shot increased neutralizing antibody responses.

22 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Study reports potently neutralizing mucosal IgA in saliva of BNT162b2 vaccine recipients

researchers determine the strong neutralizing mucosal component emanating from intramuscular administration of an mRNA vaccine.

21 Feb 2022

Full schedule of CoronaVac vaccine shown to be highly effective in children

A recent study on vaccine effectiveness showed that a complete primary immunization with CoronaVac effectively protects against severe coronavirus disease 2019 (COVID-19) for children and adolescents between 6 and 16 years of age – consistent with the results from phase 2 clinical trials. The paper is currently available on the Preprints with The Lancet* server while it undergoes peer review.

20 Feb 2022

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

A new study describes a potential new approach to treating COVID-19 in the form of single-chain fragment variable (scFv) antibodies.

20 Feb 2022

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Researchers have developed a new vaccine candidate that is specifically targeted against the SARS-CoV-2 Omicron variant.

20 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

New insights could help long-term care facilities enhance infection prevention and control measures

Findings from a study published today in the American Journal of Infection Control provide new insights that could help long-term care facilities assess the cleanliness of high-touch surfaces, and thereby enhance infection prevention and control measures designed to prevent serious diarrheal diseases and deaths among their residents.

17 Feb 2022

2022 adult immunization schedule released by ACIP

The Advisory Committee on Immunization Practices (ACIP) has released its 2022 Recommended Adult Immunization Schedule that includes changes to the zoster, pneumococcal, and hepatitis B vaccines.

17 Feb 2022

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

Researchers recently assessed SARS-CoV-2-specific humoral and cellular immune responses induced by the second and third doses of the BNT162b2 COVID-19 messenger ribonucleic acid-based vaccine in the elderly.

17 Feb 2022

Memory B cell repertoire in a longitudinal cohort of individuals receiving 3 COVID-19 mRNA vaccine doses

Researchers examined the memory B cell repertoire of individuals immunized with three doses of mRNA-based COVID-19 vaccine.

17 Feb 2022

A novel consensus-based computational pipeline that reliably predicts hACE2-RBD binding affinity

Researchers developed a novel computational model to predict the binding affinity between the hACE2 receptor and the RBD of S protein of SARS-CoV-2.

17 Feb 2022

Study looks at COVID-19 vaccine hesitancy in France and Italy

A recent study posted to Research Square* preprint server, and under consideration at the journal Scientific Reports, aimed to learn more about how and to what extent vaccine hesitancy can alter over time at the individual level by considering parameters such as dynamic preferences, news reporting, and gender influence.

16 Feb 2022

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Researchers discuss the genomic and virological characterization of SARS-CoV-2 variants among unvaccinated and vaccinated U.S military personnel.

16 Feb 2022

Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Researchers compare the incidence rate of reinfection in convalescent and unvaccinated people to that in recovered and single-dose vaccinated people.

16 Feb 2022

Study examines lyophilized mRNA-lipid nanoparticle vaccines with long-term stability

A new study explored the high immunogenicity and stability of lyophilized mRNA-LNP vaccines in relation to SARS-CoV-2.

16 Feb 2022

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

A new study evaluated the pregnancy outcomes of pregnant women in the third trimester who were infected by SARS-CoV-2 for the detection of the virus in the placenta and different samples of the newborn as well as detection of antibodies in the cord blood.

16 Feb 2022

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Researchers investigated the role of platelets in the adverse immune response against a COVID-19 vaccine.

16 Feb 2022

Study shows mRNA COVID-19 vaccination in pregnancy can prevent hospitalization among infants

A report published in the CDC’s Morbidity and Mortality Weekly Report (MMWR) shows how primary two-dose vaccination series against coronavirus disease 2019 (COVID-19) during pregnancy is linked to a reduced risk of COVID-19–associated hospitalization among infants six months of age or younger.

16 Feb 2022

Immunization News and Research

Understanding the immune responses after secondary vaccinations with Pfizer and Moderna vaccines

Study shows Pfizer-BioNTech booster protects over 65s against Delta and Omicron

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Study reports potently neutralizing mucosal IgA in saliva of BNT162b2 vaccine recipients

Full schedule of CoronaVac vaccine shown to be highly effective in children

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

New insights could help long-term care facilities enhance infection prevention and control measures

2022 adult immunization schedule released by ACIP

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

Memory B cell repertoire in a longitudinal cohort of individuals receiving 3 COVID-19 mRNA vaccine doses

A novel consensus-based computational pipeline that reliably predicts hACE2-RBD binding affinity

Study looks at COVID-19 vaccine hesitancy in France and Italy

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Study examines lyophilized mRNA-lipid nanoparticle vaccines with long-term stability

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Study shows mRNA COVID-19 vaccination in pregnancy can prevent hospitalization among infants

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