Kidney News and Research

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Tirzepatide improves kidney, cardiovascular function in patients with obesity and HFpEF

The drug tirzepatide improved kidney function and cardiovascular outcomes among patients with obesity and heart failure with preserved ejection fraction (HFpEF) compared with placebo at one year, according to featured clinical research presented at the American College of Cardiology's Annual Scientific Session (ACC.25) and simultaneously published in JACC.

31 Mar 2025

Fluid restriction does not improve health in heart failure patients

People with heart failure have long been advised to limit the amount of fluids they consume each day to help reduce congestion, or the buildup of fluid in the lungs and extremities, but that advice provides no benefit, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

AI-based imaging performs equally well as ultrasound in guiding heart procedures

Patients with narrowing of at least 50% in three major coronary arteries did equally well when treated with a minimally invasive stent placement guided either by ultrasound-based imaging or by a novel, artificial-intelligence-powered (AI), non-invasive imaging technique derived from angiography, researchers reported at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Ibuprofen suppresses sweet taste perception

Researchers explore how taste receptors react to sweet stimuli following exposure to ibuprofen.

31 Mar 2025

Investigational drug lorundrostat offers significant blood pressure drop compared with placebo

Among patients with uncontrolled hypertension, the investigational drug lorundrostat brought a significant reduction in blood pressure at 12 weeks compared with placebo, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Heart failure patients benefit from dapagliflozin after TAVR procedure

Patients with heart failure who took dapagliflozin, a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, after undergoing transcatheter aortic valve replacement (TAVR) were significantly less likely to die or experience worsening heart failure at one year compared with patients who did not take the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

New trial shows oral semaglutide reduces cardiovascular events in diabetes patients

Both the injectable and oral forms of semaglutide, a glucagon-like peptide-1 receptor agonist, have gained recent attention for their effectiveness against weight gain, high blood sugar, and even alcohol cravings.

31 Mar 2025

Semaglutide improves maximal walking distance in people with symptomatic PAD and Type 2 diabetes

Semaglutide, a glucagon-like peptide 1 (GLP-1) agonist, significantly improved maximal walking distance in people with symptomatic peripheral artery disease (PAD) and Type 2 diabetes in the first-of-its kind trial to evaluate the use of a GLP-1 agonist to manage PAD.

29 Mar 2025

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

In patients experiencing excessive bleeding during cardiac surgery, a concentrated blood product containing proteins that help the blood clot was significantly more effective and caused fewer adverse effects than frozen plasma, the standard therapy, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Rivaroxaban shown to be a viable alternative to warfarin for left ventricular thrombus

At three months of follow-up, patients hospitalized for a serious heart attack who were treated with the oral blood thinner rivaroxaban for a blood clot in the left ventricle did as well as similar patients who received standard treatment with warfarin, an older blood-thinning drug.

29 Mar 2025

Six promising biomarkers could improve early and accurate detection of kidney injury

Critical Path Institute® (C-Path) and Boston Medical Center (BMC) published results for six biomarkers that could improve the early and accurate detection of kidney injury, leading to both the development of safer medications and better health outcomes for all patients.

28 Mar 2025

Discrimination exposure found to raise anxiety, depression risks among racial and ethnic groups

A new study found that more than half of US adults encounter some form of discrimination, and that this mistreatment may fuel higher chances of depression and/or anxiety among specific racial and ethnic groups due to cultural, social, and systemic factors.

28 Mar 2025

High blood pressure can lead to structural changes in the kidneys

A research team from the Medical University of Vienna has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes.

27 Mar 2025

Conversations on AFM: Exploring the nanomechanics of living cells

In this interview Prof. Dr. Kristina Kusche-Vihrog speaks about the nanomechanics of living cells and their implications for cardiovascular disease.

From Bruker BioAFM 27 Mar 2025

Common sugar substitute increases activity in the brain's hypothalamus

Compared to sugar, consuming sucralose-a widely used sugar substitute-increases activity in the hypothalamus, a brain region that regulates appetite and body weight, according to a new USC study.

26 Mar 2025

Pass the (iodized) salt: Iodine deficiency drives frailty risk in people with diabetes

Lower iodine levels and use of non-iodized salt are linked to a higher risk of frailty in people with type 2 diabetes. This association is strongest in those with thyroid dysfunction, underscoring the importance of adequate iodine intake.

26 Mar 2025

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body.

25 Mar 2025

Increased mobility linked to lower risk of hospitalization in heart failure patients

Compared with those who spent most of their time in a single room, people with heart failure with preserved ejection fraction (HFpEF) who were able to travel outside of their home without assistance were significantly less likely to be hospitalized or die within a year, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

25 Mar 2025

Besifovir dipivoxil maleate offers comparable efficacy and improved safety for hepatitis B patients

Hepatitis B is a liver infection cause by the hepatitis B virus (HBV), and long-term hepatitis B infections that last longer than six months are considered "chronic".

24 Mar 2025

Kidney News and Research

Tirzepatide improves kidney, cardiovascular function in patients with obesity and HFpEF

Fluid restriction does not improve health in heart failure patients

AI-based imaging performs equally well as ultrasound in guiding heart procedures

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

Ibuprofen suppresses sweet taste perception

Investigational drug lorundrostat offers significant blood pressure drop compared with placebo

Heart failure patients benefit from dapagliflozin after TAVR procedure

New trial shows oral semaglutide reduces cardiovascular events in diabetes patients

Semaglutide improves maximal walking distance in people with symptomatic PAD and Type 2 diabetes

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

Rivaroxaban shown to be a viable alternative to warfarin for left ventricular thrombus

Six promising biomarkers could improve early and accurate detection of kidney injury

Discrimination exposure found to raise anxiety, depression risks among racial and ethnic groups

High blood pressure can lead to structural changes in the kidneys

Conversations on AFM: Exploring the nanomechanics of living cells

Common sugar substitute increases activity in the brain's hypothalamus

Pass the (iodized) salt: Iodine deficiency drives frailty risk in people with diabetes

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Increased mobility linked to lower risk of hospitalization in heart failure patients

Besifovir dipivoxil maleate offers comparable efficacy and improved safety for hepatitis B patients

Event guide: 8th CKD Summit 2026 eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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