Mitochondria News and Research

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Research shows how colanic acid extends lifespan in C. elegans

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

22 Dec 2020

New drug starves cancer cells by attacking mitochondria

A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria.

22 Dec 2020

Researchers discover novel mechanism by which cells turn over mitochondria

Mitochondria are cellular organelles that generate most of the energy cells need to function, and thus play an important role in maintaining cell health.

21 Dec 2020

Anti-hypertension drug may be key to extending lifespan, shows study

A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life.

18 Dec 2020

Study paves the way to a potential new treatment for rare terminal childhood illness

Scientists at the University of Exeter have identified a way to "rescue" cells that have genetically mutated, paving the way to a possible new treatment for rare terminal childhood illness such as mitochondrial disease.

18 Dec 2020

Scientists discover how a 'sociable' protein can hold clues about Alzheimer's origin

An international team of scientists led by the ESRF, the European Synchrotron, have found how the ECSIT protein dictates the behavior of proteins linked to the energy activity in mitochondria, which is largely affected in Alzheimer's disease.

16 Dec 2020

Researchers to investigate why exercise makes some people healthier than others

Why do some people benefit so much from exercise while others enjoy few health gains or even suffer harm? Does age matter when it comes to exercise's health benefits? Are there "molecular signatures" - sets of genes, proteins and other variables ¬- that reveal the answers?

11 Dec 2020

Using gene therapy to achieve the positive health effects of physical exercise

Gene therapy is the most effective method to be able to provide health benefits you normally gain through physical exercise.

5 Dec 2020

Biochemical cascade in the brain leads to the destruction of synapses in Alzheimer's

A new study on Alzheimer's disease by Scripps Research scientists has revealed a previously unknown biochemical cascade in the brain that leads to the destruction of synapses, the connections between nerve cells that are responsible for memory and cognition.

5 Dec 2020

Researchers discover why older adults are more susceptible to heart disease

A team of researchers at the University of South Florida Department of Surgery has made a key discovery as to why we become more susceptible to heart disease as we age.

3 Dec 2020

Expansion microscopy allows imaging of cell membranes in super resolution

For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes.

2 Dec 2020

Previously uncharacterized protein regulates mitochondrial NAD transporter

For their growth, cells need various nutrients and vitamins. So-called solute carriers (SLC), proteins that can transport such substances across the boundaries of cellular membranes, play a central role in metabolism.

1 Dec 2020

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

The onset of any physical exercise program causes muscle pain that can hinder movements as simple as getting up from a sofa. With time and a little persistence, the muscles become accustomed to the effort, developing more strength and endurance.

1 Dec 2020

New gene therapy approach offers promise for treating eye disease

Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an eye disease that leads to a progressive loss of vision and affects thousands of people across the globe.

26 Nov 2020

Researchers use bioinformatics methods to identify key genes in dilated cardiomyopathy

In a new publication from Cardiovascular Innovations and Applications, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Shantou, China consider the importance of mitochondrial-related genes in dilated cardiomyopathy.

19 Nov 2020

Manipulating mitochondria to improve the efficiency of neuronal reprogramming

The replacement of lost neurons is a holy grail for neuroscience. A new promising approach is the conversion of glial cells into new neurons. Improving the efficiency of this conversion or reprogramming after brain injury is an important step towards developing reliable regenerative medicine therapies.

17 Nov 2020

Metabolic biomarkers could predict COVID-19 severity

A new study suggests that metabolic biomarkers could possibly predict the severity of COVID-19 in patients.

16 Nov 2020

Machine-learning based analysis of mitochondria interaction networks to advance PD diagnosis

In a new study led by the Immune Systems Biology research group of the LIH Department of Infection and Immunity, researchers adopted a holistic machine-learning approach to elucidate how the interactions between neuronal mitochondria can serve as a powerful tool to distinguish nerve cells from Parkinson’s patients from those belonging to healthy subjects, thereby providing new insights in the pathogenesis, diagnosis and treatment of this neurodegenerative disorder.

12 Nov 2020

Lupus Research Alliance announces the 2020 Lupus Innovation Awards

The Lupus Research Alliance proudly announced today the 2020 Lupus Innovation Awards. The projects represent a wide breadth of scientific exploration in lupus, probing the development and progression of lupus while pointing to potential treatment approaches.

10 Nov 2020