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Study reveals impact of fava bean proteins on sensory cells in the mouth

Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have for the first time investigated how protein structures derived from fava beans affect a cellular model of human oral tactile cells.

25 Jan 2025

Dapagliflozin plus calorie restriction boosts remission rates in adults with type 2 diabetes and obesity

Findings indicate that dapagliflozin and calorie restriction together improve weight loss and metabolic health, increasing the likelihood of diabetes remission.

24 Jan 2025

Study reveals abelacimab’s potential to improve anticoagulation safety for AFib patients

Abelacimab, a factor XI inhibitor, demonstrated a 62–69% reduction in major bleeding compared to rivaroxaban in atrial fibrillation patients at moderate-to-high stroke risk, with comparable safety and efficacy. While ischemic stroke rates were slightly higher, they were not statistically significant, warranting further phase 3 trials for confirmation.

23 Jan 2025

Study links chemesthetic sensitivity to food preferences and consumption

Oral chemesthesis, or chemically induced tactile sensation in the mouth area, affects the consumption and recalled pleasantness of certain foods and drinks, such as chilli sauce and alcoholic beverages.

23 Jan 2025

Singapore’s respiratory health gets a boost with $10 million research grant

The Academic Respiratory Initiative for Pulmonary Health (TARIPH) Centre, a national research platform led by Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine), will lead a multi-institutional research programme after being awarded Singapore's first national research grant for respiratory health.

23 Jan 2025

Researchers investigate a new combination therapy against cancer

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer.

23 Jan 2025

New study links intestinal protein to food allergy development

When is food simply nourishing and enjoyable, and when does it provoke an allergic reaction? The answer appears to lie in the balance of microbes that live in our intestine - and a specific protein secreted by intestinal goblet cells that influences that balance.

22 Jan 2025

New Factor XI inhibitor shows superior safety in treating atrial fibrillation

Patients with atrial fibrillation are typically prescribed an anticoagulant, or blood thinner, to reduce the risk of stroke, but many may discontinue them or never receive a prescription due to concerns of increased risk of bleeding complications.

22 Jan 2025

Green tea enriched films show promise for treating oral mucositis

Green tea shines as a natural powerhouse of antioxidants, with catechins leading the charge among its polyphenols, which protect cells from oxidative stress.

22 Jan 2025

How gut microbiota impacts childhood obesity

Gut microbiota plays a critical role in childhood obesity by influencing energy metabolism, inflammation, and appetite regulation, with emerging therapeutic strategies like probiotics, dietary interventions, and fecal microbiota transplantation showing promise.

21 Jan 2025

Azvudine beats paxlovid in reducing COVID-19 deaths

In hospitalized COVID-19 patients, azvudine shows lower all-cause mortality and fewer adverse events than Paxlovid, with added antitumor effects observed.

21 Jan 2025

What drives acne relapse? New study explores isotretinoin outcomes

New research suggests that increasing cumulative isotretinoin dosage could significantly reduce acne recurrence and the need for retreatment, offering hope for long-term skin clarity.

20 Jan 2025

Breakthrough study maps critical structure of Nipah virus polymerase

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.

20 Jan 2025

Study uncovers key role of NSP4 in rotavirus disease severity

Researchers at Baylor College of Medicine and collaborating institutions have improved our understanding of how rotavirus, the most common cause of acute gastroenteritis in children, makes people sick.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

Non-toxic bacterial therapy shows promise for targeting tumors

A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made "exciting," patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors.

16 Jan 2025

AstraZeneca's Pioneering Research in Heart Failure and ATTR-CM

Mina Makar highlights AstraZeneca's commitment to advancing heart failure research and innovative therapies, addressing critical needs in cardiovascular health.

16 Jan 2025

PFAS in US water linked to increased cancer risk

A study links PFAS contamination in drinking water to increased cancer risks, highlighting significant impacts on digestive, endocrine, and respiratory systems.

16 Jan 2025

Pheno Therapeutics receives clinical trial authorization for novel multiple sclerosis therapeutic

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics for the treatment of neurological diseases, announced today it has received clinical trial authorization (CTA) from the UK’s MHRA (Medicines and Healthcare products Regulatory Agency) for its lead candidate, PTD802.

15 Jan 2025

Nicotine pouch use among soldiers significantly higher than civilians

American soldiers are 10 times more likely to use nicotine pouches that can cause serious health issues than average American adults, according to a survey of military personnel at Fort Liberty, the largest American military base.

15 Jan 2025