Polymerase News and Research

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New immunosensor could be a fast, inexpensive, and convenient tool to detect COVID-19

A new immunosensor based on Quenchbody technology shows great potential as a fast, inexpensive, and convenient tool to detect SARS-CoV-2.

15 Dec 2022

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

Researchers evaluated the emergence and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in Canada.

15 Dec 2022

How do predicted ecological niches of the mpox virus compare with that of 99 mammal species?

Researchers compared ecological niches to identify probable mpox virus reservoir hosts.

15 Dec 2022

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Researchers estimated influenza VE in patients aged ≥6 months seeking outpatient care for ARI due to the influenza A(H3N2) virus between October 2021 and April 2022 in the United States (US).

15 Dec 2022

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Researchers evaluated the change in symptoms and risk factors associated with positive SARS-CoV-2 tests during the COVID-19 pandemic and compared it to those associated with positive tests of other respiratory viruses among residents of King County, Washington, in the United States.

14 Dec 2022

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Researchers isolated SARS-CoV-2 spike protein-targeted mAbs from convalescent healthcare workers, emphasizing the IGHV1-69 gene, the gene with the greatest structural and allelic variation.

14 Dec 2022

Characterization of immune evasion and cell entry for new variants: BQ.1.1, XBB.1, and BR.2.1

In a recent study posted to the medRxiv* preprint server, researchers in Australia and Switzerland evaluated the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in community-based settings of the United States (US).

13 Dec 2022

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Researchers provided an overview of existing molecular methods for mpox virus detection.

13 Dec 2022

Immunogenicity of SARS-CoV-2 antibody response in immune naïve children and adults

Researchers compare the contribution of antibodies against the SARS-CoV-2 receptor binding domain in vaccinated and naturally infected adults and children.

12 Dec 2022

What is the incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir?

Researchers evaluated the incidence of COVID-19 rebound among SARS-CoV-2 -positive patients treated with oral antiviral drugs such as nirmatrelvir-ritonavir combination and molnupiravir.

12 Dec 2022

Reports of Mpox disease following recent vaccination

The risk of infection and development of severe symptoms for Mpox remains, even after vaccination

11 Dec 2022

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

Researchers construct a recombinant host-range restricted vaccinia virus Ankara (rMVAs) expressing the spike proteins of several SARS-CoV-2 variants.

11 Dec 2022

Study of 1.1 million children finds no association between SARS-CoV-2 infection and type 1 diabetes risk

Researchers investigate whether the risk of new-onset type 1 diabetes is elevated by SARS-CoV-2 infections among children living in Denmark.

11 Dec 2022

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Oregon Health & Science University researchers and partners are developing what could become the first-ever treatment against the debilitating joint pain that can last months or years after becoming infected with the emerging Chikungunya virus.

9 Dec 2022

Exploring the well-being and health of SARS-CoV-2-positive children and young people

Researchers explored the well-being and health of non-hospitalized young individuals and children following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

9 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

Researchers reported the immunogenicity, efficacy, and safety of the MVA-BN (modified vaccinia Ankara-Bavarian Nordic)-RSV (respiratory syncytial virus) vaccine against RSV-A (RSV subtype A) Memphis 37b strain in a human challenge trial.

7 Dec 2022

Researchers explore the correlation between the dynamic shedding pattern of SARS-CoV-2 and viral load

Researchers attempted to establish an association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load, indicating its ribonucleic acid (RNA) levels, and the presence of infectious virions.

7 Dec 2022

Research reveals a novel viral strategy in modulating stress granule formation to promote virus infection

Researchers illustrated a novel strategy likely employed by viruses to promote infection.

6 Dec 2022

Co-infecting pathogens and the microbiome from SARS-CoV-2 positive and negative samples

Researchers evaluated co-infections in SARS-CoV-2-infected patients.

6 Dec 2022

Polymerase News and Research

New immunosensor could be a fast, inexpensive, and convenient tool to detect COVID-19

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

How do predicted ecological niches of the mpox virus compare with that of 99 mammal species?

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Characterization of immune evasion and cell entry for new variants: BQ.1.1, XBB.1, and BR.2.1

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Immunogenicity of SARS-CoV-2 antibody response in immune naïve children and adults

What is the incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir?

Reports of Mpox disease following recent vaccination

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

Study of 1.1 million children finds no association between SARS-CoV-2 infection and type 1 diabetes risk

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Exploring the well-being and health of SARS-CoV-2-positive children and young people

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

Researchers explore the correlation between the dynamic shedding pattern of SARS-CoV-2 and viral load

Research reveals a novel viral strategy in modulating stress granule formation to promote virus infection

Co-infecting pathogens and the microbiome from SARS-CoV-2 positive and negative samples

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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