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p38 MAPK drives epigenetic activation of fibrotic genes in lung fibroblasts

A new research paper was published in Volume 18 of Aging-US on March 3, 2026, titled "P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts."

10 Mar 2026

Cellular energy changes may help detect early-stage major depression

Researchers may have discovered a new way to diagnose and treat major depression at the earliest stage of the condition, giving patients the best opportunity for recovery.

10 Mar 2026

Air pollution may be lowering global IQ and widening inequality, researchers warn

Researchers argue that exposure to fine particulate air pollution (PM2.5) may affect cognitive function and intelligence, potentially causing large population-level losses in global IQ. Using modelling based on published exposure–response data, the authors estimate that pollution could be associated with tens of billions of IQ points lost worldwide, with the largest impacts in lower-income regions.

10 Mar 2026

How social and environmental exposures across life influence mental health risk

Researchers outline how the exposome framework, which captures the totality of environmental exposures across the lifespan, can help explain how non-genetic factors shape mental health risk and resilience. The perspective highlights how integrating environmental, biological, and social data could improve prevention strategies, research models, and personalized mental health care.

10 Mar 2026

Postbiotics may help treat PCOS by restoring microbiome balance

Emerging studies suggest postbiotics could aid PCOS management by restoring gut microbiome balance and enhancing insulin sensitivity and hormonal regulation.

10 Mar 2026

Adelaide University decodes the secrets of cancer survival

A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.

10 Mar 2026

UH psychology professor questions claim that multilingualism protects against brain aging

University of Houston professor of psychology Arturo Hernandez is disputing a high-profile study published in the journal Nature Aging claiming that people who live in multilingual countries show healthier brain aging.

9 Mar 2026

Largest genetic study classifies 14 psychiatric disorders into five major groups

Although mental disorders have multifactorial causes, genetics can explain some of them, yet this field remains largely unexplored in terms of guiding diagnoses and treatments.

9 Mar 2026

Preventing postoperative rebleeding in intracerebral hemorrhage surgery

Intracerebral hemorrhage (ICH) is the stroke subtype with the highest mortality and disability rates, and early hematoma evacuation is crucial for improving prognosis.

9 Mar 2026

Protein aggregates in the liver may protect against alcohol-induced damage

Alcohol-associated liver disease (ALD) remains a leading cause of cirrhosis and liver-related mortality worldwide, with few effective therapies.

9 Mar 2026

Spiritual care should be routine for patients with neurological diseases

People living with neurological diseases such as Parkinson's disease, dementia and epilepsy face not only physical decline, but also profound questions about identity, purpose, and meaning.

9 Mar 2026

Pregnancy complications increase heart health risks for women with high stress

Women who experience pregnancy complications, like preeclampsia, pre-term birth, stillbirth or having a baby that is small for gestational age, may face an increased risk for cardiovascular disease later in life.

9 Mar 2026

Yale study identifies parent stress as an obesity risk factor

In recent years, rates of childhood obesity have been rising, with the U.S. Centers for Disease Control estimating in 2024 that approximately one in five children and adolescents met the clinical definition of obese.

9 Mar 2026

How somatic mutations shape disease and reveal new drug targets

Researchers reviewed how somatic mutations accumulate in normal and diseased tissues, showing that natural selection can expand clones that influence disease risk, tissue adaptation, or cellular resilience. The study proposes somatic genomics as a powerful strategy to uncover disease mechanisms and identify new therapeutic targets across multiple conditions.

8 Mar 2026

Med14 protein drives GLP-1 benefits in pancreatic beta cells

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health.

6 Mar 2026

Ketone body can strengthen the fitness and antitumor activity of CAR T cells

A naturally occurring byproduct of liver metabolism–the ketone body, β-hydroxybutyrate (BHB)–can strengthen the fitness and antitumor activity of CAR T cells.

6 Mar 2026

New optovolution technique uses light to guide protein evolution

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

6 Mar 2026

NIH grant supports research on immune-related receptor in neurons

Florida Atlantic University has received a $2.4 million grant from the National Institutes of Health to investigate how an immune-related receptor in neurons plays a fundamental role in brain function, behavior and psychiatric health.

6 Mar 2026

PET imaging reveals molecular mechanism behind ketamine's antidepressant effects

Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and approximately 30% of patients develop treatment-resistant depression (TRD), a condition that does not respond adequately to conventional antidepressant therapies.

6 Mar 2026

Disrupted iron levels after SARS-CoV-2 infection may trigger long COVID

Problems with iron levels in the blood and the body's ability to regulate this important nutrient as a result of SARS-CoV-2 infection could be a key trigger for long COVID, new research has discovered.

6 Mar 2026